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(2-Chloropyrimidin-4-yl)methanol

(2-Chloropyrimidin-4-yl)methanol Structure
(2-Chloropyrimidin-4-yl)methanol structure
CAS No.
34953-87-2
Chemical Name:
(2-Chloropyrimidin-4-yl)methanol
Synonyms
(2-chloropyrimidin-4-yl)methanol;2-Chloropyrimidine-4-methanol;4-Pyrimidinemethanol, 2-chloro-;(2-chloro-4-pyrimidinyl)methanol;4-Pyrimidinemethanol, 2-chloro- (9CI);(2-chloropyrimidin-4-yl)methanol - [C86548]
CBNumber:
CB41081978
Molecular Formula:
C5H5ClN2O
Molecular Weight:
144.56
MDL Number:
MOL File:
34953-87-2.mol
MSDS File:
SDS
Last updated:2026-08-10 15:17:32
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(2-Chloropyrimidin-4-yl)methanol Properties

Boiling point 341.8±17.0 °C(Predicted)
Density 1.422±0.06 g/cm3(Predicted)
storage temp. 2-8°C, stored under nitrogen
pka 13.05±0.10(Predicted)
Appearance White to yellow Solid
InChI InChI=1S/C5H5ClN2O/c6-5-7-2-1-4(3-9)8-5/h1-2,9H,3H2
InChIKey POXLTMBMLWQOQG-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC(CO)=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

(2-Chloropyrimidin-4-yl)methanol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FC63484 (2-Chloropyrimidin-4-yl)methanol 34953-87-2 5mg $900 2026-06-04 Buy
Biosynth FC63484 (2-Chloropyrimidin-4-yl)methanol 34953-87-2 50mg $900 2026-06-04 Buy
Biosynth FC63484 (2-Chloropyrimidin-4-yl)methanol 34953-87-2 25mg $900 2026-06-04 Buy
Biosynth FC63484 (2-Chloropyrimidin-4-yl)methanol 34953-87-2 10mg $900 2026-06-04 Buy
Biosynth FC63484 (2-Chloropyrimidin-4-yl)methanol 34953-87-2 100mg $900 2026-06-04 Buy
Product number Packaging Price Buy
FC63484 5mg $900 Buy
FC63484 50mg $900 Buy
FC63484 25mg $900 Buy
FC63484 10mg $900 Buy
FC63484 100mg $900 Buy

(2-Chloropyrimidin-4-yl)methanol Chemical Properties, Uses, Production

Chemical Properties

yellow solid

Uses

(2-Chloropyrimidin-4-yl)methanol is a heterocyclic compound containing reactive chlorine and hydroxyl functional groups. It can be used as a pharmaceutical intermediate in the preparation of active substances such as MCL-1 inhibitors.

Synthesis

The method for the synthesis of (2-chloropyrimidin-4-yl)methanol is as follows: To a solution of 2-chloropyrimidine-4-carboxylic (isobutyl carbonic) anhydride (16.3 g, 63.0 mmol) in Tetrahydrofuran (200 mL) and water (20 mL) was added sodium borohydride (4.7 g, 124.8 mmol) at 0 °C dropwise. Then the mixture was stirred at 0 °C for 1 hour. The reaction mixture was quenched with aqueous NH4Cl (20 mL) and diluted with water (100 mL), extracted with ethyl acetate (100 mL x 2), washed with brine (50 mL x 2), dried over Na2SO4, filtered and concentrated to residue which was purified by silica gel chromatography (solvent gradient: 0- 50% ethyl acetate in petroleum ether) to afford (2-chloropyrimidin-4-yl)methanol (3 g, 33% yield) as a yellow solid.
synthesis of (2-chloropyrimidin-4-yl)methanol

(2-Chloropyrimidin-4-yl)methanol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloro-4-(chloromethyl)pyrimidine

(2-Chloropyrimidin-4-yl)methanol Suppliers

Global Suppliers ( 59)
Supplier Tel Email Country ProdList Advantage
Hangzhou Milon Pharmatech Co.,Ltd. 18083715844 sales@milonpharm.com China 346 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Shanghai Boyners Pharm-Tech Co., Ltd. 13817873692 mkt@boynerspharm.com China 1707 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Shandong utilizing biological technology co., LTD 18669728830 15966937598 3407650895@qq.com China 5183 58
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9959 58
ShanghaiFineBiotechCoLtd +8618717800556 18717800556 sales@finebioetch.com CHINA 318 58
Accela ChemBio Inc. +1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10452 58
Supplier Advantage
Hangzhou Milon Pharmatech Co.,Ltd. 58
Bide Pharmatech Ltd. 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Shanghai Boyners Pharm-Tech Co., Ltd. 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Shandong utilizing biological technology co., LTD 58
Suzhou Rovathin Foreign Trade Co.,Ltd 58
ShanghaiFineBiotechCoLtd 58
Accela ChemBio Inc. 58
Accela ChemBio Co.,Ltd. 58

View Latest Price from (2-Chloropyrimidin-4-yl)methanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Pyrimidinemethanol, 2-chloro- (9CI) pictures 2024-08-08 4-Pyrimidinemethanol, 2-chloro- (9CI)
34953-87-2
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

(2-Chloropyrimidin-4-yl)methanol Spectrum

4-Pyrimidinemethanol, 2-chloro- (9CI)(34953-87-2)1HNMR

34953-87-2 ((2-Chloropyrimidin-4-yl)methanol) Related Search:

2-Chloropyrimidine-4-carboxylic acid methyl 2-chloropyrimidine-4-carboxylate Ethyl 2-chloropyrimidine-4-carboxylate 4-Pyrimidinemethanol, 2-chloro-5-fluoro- 2-Chloro-4-methoxymethyl-pyrimidine
Pyrimidine, 2-chloro-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-

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4-Pyrimidinemethanol, 2-chloro- (9CI) 4-Pyrimidinemethanol, 2-chloro- (2-chloro-4-pyrimidinyl)methanol 2-Chloropyrimidine-4-methanol (2-chloropyrimidin-4-yl)methanol - [C86548] (2-chloropyrimidin-4-yl)methanol 34953-87-2 PYRIMIDINE