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O-Phospho-L-tyrosine

CAS No.
21820-51-9
Chemical Name:
O-Phospho-L-tyrosine
Synonyms
PHOSPHOTYROSINE;O-Phosphotyrosine;p-Tyr;H-TYR(P)-OH;Phospho-Tyr;H-Tyr(PO3)-OH;H-TYR(H2PO3)-OH;H-TYR(PO3H2)-OH;L-Tyr(H2PO3)-OH;H-L-Tyr(PO3H2)-OH
CBNumber:
CB4113874
Molecular Formula:
C9H12NO6P
Molecular Weight:
261.17
MDL Number:
MFCD00002603
MOL File:
21820-51-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:16

O-Phospho-L-tyrosine Properties

Melting point 226-227°C
Boiling point 521.7±60.0 °C(Predicted)
Density 1.591±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Aqueous Acid (Slightly), Water (Slightly, Sonicated)
form Solid
pka 1.24±0.30(Predicted)
color White to Off-White
optical activity -9.6° (C=0.01 g/ml, 1N HCL)
BRN 3150815
InChI 1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1
InChIKey DCWXELXMIBXGTH-QMMMGPOBSA-N
SMILES N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O
CAS DataBase Reference 21820-51-9(CAS DataBase Reference)
FDA UNII 2R86C98KDX
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  21/22
Safety Statements  36/37
WGK Germany  3
10-21
HS Code  29225090
Storage Class 11 - Combustible Solids
REACH Registrations Active

O-Phospho-L-tyrosine price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P9405 O-Phospho-L-tyrosine 21820-51-9 100mg $94 2026-04-30 Buy
Sigma-Aldrich P9405 O-Phospho-L-tyrosine 21820-51-9 1g $452 2026-04-30 Buy
Sigma-Aldrich 72851 O-Phospho-L-tyrosine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland 21820-51-9 100 mg $495 2026-04-30 Buy
TCI Chemical P0959 O-Phospho-L-tyrosine >97.0%(HPLC)(T) 21820-51-9 100mg $84 2026-04-30 Buy
Cayman Chemical 23064 O-Phospho-L-Tyrosine ≥95% 21820-51-9 100mg $41 2026-04-30 Buy
Product number Packaging Price Buy
P9405 100mg $94 Buy
P9405 1g $452 Buy
72851 100 mg $495 Buy
P0959 100mg $84 Buy
23064 100mg $41 Buy

O-Phospho-L-tyrosine Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

O-Phospho-L-tyrosine is used in the study of tyrosine-phosphorylation, which has been linked to the malignant transformation of cells by various RNA tumor viruses. Plays a role in signal transduction.

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid that is L-tyrosine phosphorylated at the phenolic hydroxy group.

Biological Activity

Phosphotyrosine acts as a docking site in protein regulation by stimulating interaction between tyrosine-phosphorylated proteins and phosphotyrosine domains of other proteins.

Purification Methods

Purify it by recrystallisation from H2O or H2O/EtOH. [Levene & Schormüller J Biol Chem 100 583 1933, Posternak & Graff Helv Chim Acta 28 1258 1945, Beilstein 14 III 1510.]

O-Phospho-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 182)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
H-TYR(H2PO3)-OH H-TYR(P)-OH H-TYR(PO3H2)-OH L-3-[4-HYDROXYPHENYL]ALANINE 4'-PHOSPHATE L-TYROSINE O-PHOSPHATE H-Tyr(PO3)-OH H-L-Tyr(PO3H2)-OH L-Phosphotyrosine, (S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic acid (S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic ac (S)-2-AMINO-3-(4-PHOSPHONOOXY-PHENYL)-PROPIONIC ACID O-PHOSPHORYL-L-TYROSINE (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid (2S)-2-amino-3-(4-phosphonooxyphenyl)propionic acid (2S)-2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid L-3-(4-Hydroxyphenyl)alanine 4μ-phosphate, L-Tyrosine-O-phosphate L-Tyrosine-O-phosphoric acid O-Phosphono-L-tyrosine O-Phosphonotyrosine Phosphoric acid 4-[(S)-2-carboxy-2-aminoethyl]phenyl ester Phospho-Tyr p-Tyr L-Tyr(H2PO3)-OH O-Phospho-L-tyrosine≥ 99% (TLC) (S)-2-aMino-3-(4-(phosphonooxy)phenyl)propanoic acid O(4)-phospho-L-tyrosine O-Phospho-L-tyrosine> L-Tyrosine, O-phosphono- O-PHOSPHO-L-TYROSINE USP/EP/BP Phosphotyrosine, BSA Conjugated Phospho-L-tyrosine Mouse Anti-Phosphotyrosine antibody Rabbit Anti-Phospho-Tyrosine/Bio Conjugated antibody Rabbit Anti-Phospho-Tyrosine antibody O-Phospho-L-tyrosine O-Phosphotyrosine PHOSPHOTYROSINE O-Phospho-L-tyrosine 21820-51-9 BioChemical Amino Acids and Peptides Biochemicals and Reagents Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Modified Amino Acids I - Z Substrate Analogs Amino Acids Biochemistry Biological-modified Amino Acids Amino Acids & Derivatives Aromatics Chiral Reagents Phosphorylating and Phosphitylating Agents