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ChemicalBook >> CAS DataBase List >>2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)-

2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)-

2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- Structure
2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- structure
CAS No.
2416338-55-9
Chemical Name:
2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)-
Synonyms
Microtubule inhibitor 5;2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)-
CBNumber:
CB412608049
Molecular Formula:
C22H15FN2O4
Molecular Weight:
390.36
MDL Number:
MOL File:
2416338-55-9.mol
MSDS File:
SDS
Last updated:2026-05-11 19:39:08
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2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- Properties

Boiling point 695.8±55.0 °C(Predicted)
Density 1.371±0.06 g/cm3(Predicted)
pka 11.38±0.20(Predicted)

2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- Chemical Properties, Uses, Production

Uses

Microtubule inhibitor 5 (compound 17f) is a potent microtubule inhibitor. Microtubule inhibitor 5 shows cytotoxicity with an IC50 value of 154.5 nM for NCI-H460 cells. Microtubule inhibitor 5 shows good cell permeability[1].

References

[1] Ding Z, et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435. DOI:10.1016/j.bmc.2020.115435

2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Microtubule inhibitor 5 pictures 2026-05-11 Microtubule inhibitor 5
2416338-55-9
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

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2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)- Microtubule inhibitor 5 2416338-55-9