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ChemicalBook >> CAS DataBase List >>Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)-

Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)-

Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- Structure
Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- structure
CAS No.
2476490-18-1
Chemical Name:
Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)-
Synonyms
PCSK9 modulator-3;Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)-
CBNumber:
CB412693490
Molecular Formula:
C16H9F2N3O
Molecular Weight:
297.26
MDL Number:
MOL File:
2476490-18-1.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- Properties

Boiling point 572.7±58.0 °C(Predicted)
Density 1.531±0.06 g/cm3(Predicted)
pka 8.78±0.10(Predicted)

Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- Chemical Properties, Uses, Production

Uses

PCSK9 modulator-3 (Compound 13) is a potent modulator of PCSK9 with an EC50 value of 2.46 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-3 has the potential for the research of hyperlipidemia[1].

References

[1] Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678. DOI:10.1016/j.ejmech.2020.112678

Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PCSK9 modulator-3 pictures 2026-04-20 PCSK9 modulator-3
2476490-18-1
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

2476490-18-1 (Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)-) Related Search:

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Methanone, (6-fluoro-1H-benzimidazol-2-yl)(7-fluoro-1H-indol-3-yl)- PCSK9 modulator-3 2476490-18-1