2-Benzothiazolamine,7-chloro-(9CI)
- CAS No.
- 20358-01-4
- Chemical Name:
- 2-Benzothiazolamine,7-chloro-(9CI)
- Synonyms
- 2-Amino-7-chlor-benzthiazol;2-Amino-7-chlorobenzothiazol;7-Chlorobenzothiazol-2-amine;2-Amino-7-chlorobenzothiazole;2-Benzothiazolamine, 7-chloro-;7-Chloro-benzothiazol-2-ylamine;7-Chlorobenzo[d]thiazol-2-aMine;7-Chlorobenzo[d]thiazole-2-amine;7-Chloro-1,3-benzothiazol-2-amine;2-Benzothiazolamine,7-chloro-(9CI)
- CBNumber:
- CB41301416
- Molecular Formula:
- C7H5ClN2S
- Molecular Weight:
- 184.65
- MDL Number:
- MFCD01663341
- MOL File:
- 20358-01-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 7-Chlorobenzo[d]thiazol-2-amine | VAA35801 | 0.5g | $306.8 |
| 7-Chlorobenzo[d]thiazol-2-amine | VAA35801 | 5g | $1357 |
| 7-Chlorobenzo[d]thiazol-2-amine | 301202 | 250.00mg | $80 |
| 7-Chlorobenzo[d]thiazol-2-amine | 301202 | 1.00g | $158 |
| 7-Chlorobenzo[d]thiazol-2-amine | 301202 | 5.00g | $498 |
| More product size | |||
| Melting point | 177-178 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 344.3±34.0 °C(Predicted) |
| Density | 1.532±0.06 g/cm3(Predicted) |
| storage temp. | RT, protect from light |
| pka | 2.68±0.30(Predicted) |
| Appearance | Light yellow to light brown Solid |
| FDA UNII | 4TS6N372WQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H302-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 29342000 |
2-Benzothiazolamine,7-chloro-(9CI) price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | VAA35801 | 7-Chlorobenzo[d]thiazol-2-amine | 20358-01-4 | 0.5g | $306.8 | 2026-06-05 | Buy |
| Biosynth | VAA35801 | 7-Chlorobenzo[d]thiazol-2-amine | 20358-01-4 | 5g | $1357 | 2026-06-05 | Buy |
| Matrix Scientific | 301202 | 7-Chlorobenzo[d]thiazol-2-amine | 20358-01-4 | 250.00mg | $80 | 2026-05-19 | Buy |
| Matrix Scientific | 301202 | 7-Chlorobenzo[d]thiazol-2-amine | 20358-01-4 | 1.00g | $158 | 2026-05-19 | Buy |
| Matrix Scientific | 301202 | 7-Chlorobenzo[d]thiazol-2-amine | 20358-01-4 | 5.00g | $498 | 2026-05-19 | Buy |
2-Benzothiazolamine,7-chloro-(9CI) Chemical Properties,Uses,Production
Synthesis
4947-89-1
20358-00-3
20358-01-4
General procedure for the synthesis of 2-amino-5-chlorobenzothiazole and 7-chlorobenzo[d]thiazol-2-amine from 3-chlorobenzothiourea: 3-chlorobenzothiourea (105 mg, 0.56 mmol) was dissolved in 10 mL of acetic acid. Benzyltrimethylammonium tribromide (329 mg, 0.84 mmol) was added and the reaction mixture was stirred at room temperature for 14 hours. After completion of the reaction, the acetic acid was removed by distillation under reduced pressure. The residue was redissolved in 15 mL of dichloromethane (DCM) and 10 mL of 0.5 N aqueous sodium hydroxide was added. The aqueous phase was extracted with dichloromethane (2 x 15 mL). The organic layers were combined, filtered through a phase separator and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography using pentane-ethyl acetate (12:5) as eluent to afford the target product 2-amino-5-chlorobenzothiazole (61 mg, 59% yield) as a white solid. The structure of the product was analyzed by 1H NMR (500 MHz, CD3OD) δ 7.05 (dd, J = 8.4, 2.0 Hz, 1H), 7.35 (d, J = 2.0 Hz, 1H), 7.53 (d, J = 8.4 Hz, 1H); 13C NMR (125 MHz, CD3OD) δ 117.41, 121.45, 121.60 129.37, 131.55, 153.24, 170.04; Mass Spectrometry (ESI): m/z 185 [M + H]+ confirmed.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 14, p. 4839 - 4843
[2] Yakugaku Zasshi, 1957, vol. 77, p. 649,651
[3] Chem.Abstr., 1957, p. 16435
2-Benzothiazolamine,7-chloro-(9CI) Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing Taiya Jie Technology Development Co., Ltd. | 021-33690831-8001 13552411790 | postmaster@tyjchem.cn | China | 1542 | 55 |
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