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2,4-Dichloropyridine-3-carboxaldehyde

2,4-Dichloropyridine-3-carboxaldehyde structure

CAS No.: 134031-24-6

Chemical Name:: 2,4-Dichloropyridine-3-carboxaldehyde

Synonyms: 2,4-dichloronicotinaldehyde;EOS-61543;2,4-Dichloro-3-formylpyridine;2,4-dichloronicotinaldehyde (en);2,4-Dichloro-pyridin-3-carbaldehyde;2,4-DICHLOROPYRIDINE-3-CARBOXALDEHYDE;3-Pyridinecarboxaldehyde,2,4-dichloro;2,4-dichloro-3-pyridine Carboxaldehyde;2,4-Dichloropyridine-3-carboxaldehyde 97%;2,4-Dichloropyridine-3-carboxaldehyde, CAS 134031-24-6

CBNumber:: CB4132686

Molecular Formula:: C6H3Cl2NO

Molecular Weight:: 176

MDL Number:: MFCD07437909

MOL File:: 134031-24-6.mol

MSDS File:: SDS

Last updated:2026-01-13 11:18:56

Product description	Number	Pack Size	Price
2,4-Dichloropyridine-3-carboxaldehyde 97%	711365	500mg	$97.2
2,4-Dichloro-3-pyridinecarboxaldehyde >98.0%(GC)	D5076	1g	$36
2,4-Dichloro-3-pyridinecarboxaldehyde >98.0%(GC)	D5076	5g	$138
2,4-Dichloronicotinaldehyde	D438468	10mg	$45
2,4-Dichloronicotinaldehyde	X9868	1g	$54
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2,4-Dichloropyridine-3-carboxaldehyde Properties

Melting point	72-75℃
Boiling point	261.8±35.0 °C(Predicted)
Density	1.488±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	-1.17±0.10(Predicted)
form	powder to crystal
color	White to Orange to Green
Sensitive	Air Sensitive
InChI	InChI=1S/C6H3Cl2NO/c7-5-1-2-9-6(8)4(5)3-10/h1-3H
InChIKey	GWBHJHIZHNTJLA-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=CC(Cl)=C1C=O
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P280a-P304+P340-P405-P501a-P261-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Risk Statements

22-36/37/38

Safety Statements

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

HazardClass

IRRITANT

HS Code

2933399990

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

2,4-Dichloropyridine-3-carboxaldehyde price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	711365	2,4-Dichloropyridine-3-carboxaldehyde 97%	134031-24-6	500mg	$97.2	2023-01-07	Buy
TCI Chemical	D5076	2,4-Dichloro-3-pyridinecarboxaldehyde >98.0%(GC)	134031-24-6	1g	$36	2026-03-19	Buy
TCI Chemical	D5076	2,4-Dichloro-3-pyridinecarboxaldehyde >98.0%(GC)	134031-24-6	5g	$138	2026-03-19	Buy
TRC	D438468	2,4-Dichloronicotinaldehyde	134031-24-6	10mg	$45	2021-12-16	Buy
AK Scientific	X9868	2,4-Dichloronicotinaldehyde	134031-24-6	1g	$54	2021-12-16	Buy

Product number	Packaging	Price	Buy
711365	500mg	$97.2	Buy
D5076	1g	$36	Buy
D5076	5g	$138	Buy
D438468	10mg	$45	Buy
X9868	1g	$54	Buy

2,4-Dichloropyridine-3-carboxaldehyde Chemical Properties,Uses,Production

Application

2,4-Dichloronicotinaldehyde, also known as 2,4-dichloronicotinaldehyde, can be obtained by reacting 2,4-dichloropyridine with a strong base to obtain (2,4-4-dichloro-3-pyridyl)lithium, and then reacting it with DMF.

Chemical Properties

Yellow solid

Synthesis

To a solution of 2,4-dichloropyridine (2 g, 13.51 mmol) in tetrahydrofuran (20 mL) at -78° C added LDA in THF/heptane/ethylbenzene (2M, 8.11 mL, 16.22 mmol) and the solution was stirred for 30 min. DMF (10.46 mL, 135 mmol) was added and the solution was stirred for 1 h and then warmed RT. The reaction mixture was quenched with saturated NH4Cl solution and diluted with ethyl acetate (50 mL). The organic layer was washed with saturated NaHCO3 (2*10 mL), water (20 mL), dried over Na2SO4, and concentrated under reduced pressure to afford 2,4-dichloronicotinaldehyde (2 g, 11.36 mmol, 84% yield). 2,4-Dichloropyridine-3-carboxaldehyde

References

[1] Tetrahedron Letters, 2011, vol. 52, # 4, p. 523 - 525
[2] Organic Process Research and Development, 2018, vol. 22, # 8, p. 978 - 990
[3] Patent: US2013/237555, 2013, A1. Location in patent: Paragraph 0273
[4] Patent: WO2015/38112, 2015, A1. Location in patent: Page/Page column 126
[5] Patent: WO2018/109050, 2018, A1. Location in patent: Paragraph 0286-0297

2,4-Dichloropyridine-3-carboxaldehyde Preparation Products And Raw materials

Raw materials

Methyl formate N-Formylpiperidine 2,4-Dichloropyridine N,N-Dimethylformamide Ethyl formate

Tetrahydrofuran Lithium diisopropylamide Heptane Ethylbenzene

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Preparation Products

HDH-PHARMA 26173 4H-Pyrazolo[4,3-c]pyridin-4-one,1,5-dihydro- 2,4-Dichloropyridine-3-methanol

2,4-Dichloropyridine-3-carboxaldehyde Suppliers

Global( 213)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
PNP Biotech Co. Ltd	+8618516098983	sales@pnpbiotech.com	China	1001	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29824	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58

Supplier	Advantage
PNP Biotech Co. Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58

View Lastest Price from 2,4-Dichloropyridine-3-carboxaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	2,4-Dichloropyridine-3-carboxaldehyde 134031-24-6	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2024-03-28	2,4-Dichloropyridine-3-carboxaldehyde 134031-24-6	US $0.00 / kg	25kg	98%	Inquiry	PNP Biotech Co. Ltd
2022-02-25	2,4-Dichloro-3-pyridine carboxaldehyde 134031-24-6	US $200.00 / Kg/Bag	1KG	99%	10Tons	Hebei Senko Biotechnology Co., Ltd.

2,4-Dichloropyridine-3-carboxaldehyde
134031-24-6
US $1.10 / g
99.00%
Dideu Industries Group Limited

2,4-Dichloropyridine-3-carboxaldehyde
134031-24-6
US $0.00 / kg
98%
PNP Biotech Co. Ltd

2,4-Dichloro-3-pyridine carboxaldehyde
134031-24-6
US $200.00 / Kg/Bag
99%
Hebei Senko Biotechnology Co., Ltd.

2,4-Dichloropyridine-3-carboxaldehyde Spectrum

2,4-Dichloropyridine-3-carboxaldehyde(134031-24-6)¹HNMR

134031-24-6(2,4-Dichloropyridine-3-carboxaldehyde)Related Search:

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Dichlorodimethylsilane 2-Chloro-5-chloromethylpyridine 3-Aminopyridine 3,4-Dichloropyridine 2,4-Dichlorobenzoic acid

Thionyl chloride Sodium dichloroisocyanurate Dichloroethane N,N-Dimethylacetamide ETHYL 2,4-DICHLORO-6-METHYLPYRIDINE-3-CARBOXYLATE

2,4-Dichloropyridine-3-carboxylic acid 5,6-Dichloropyridine-3-carboxaldehyde 2,6-Dichloropyridine-4-carboxaldehyde ,98%,2,6-DICHLOROPYRIDINE-4-CARBOXALDEHYDE

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2,4-DICHLOROPYRIDINE-3-CARBOXALDEHYDE 2,4-dichloronicotinaldehyde 2,4-dichloro-3-pyridine Carboxaldehyde 3-Pyridinecarboxaldehyde,2,4-dichloro 2,4-dichloronicotinaldehyde (en) 2,4-Dichloropyridine-3-carboxaldehyde 97% 2,4-Dichloro-pyridin-3-carbaldehyde EOS-61543 2,4-Dichloro-3-formylpyridine 2,4-Dichloropyridine-3-carboxaldehyde ISO 9001：2015 REACH 2,4-Dichloropyridine-3-carboxaldehyde, CAS 134031-24-6 134031-24-6 C6H3NOCl2 Pyridines