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ChemicalBook >> CAS DataBase List >>2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate

2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate

2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Structure
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate structure
CAS No.
2761458-86-8
Chemical Name:
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate
Synonyms
YK009;decyl 4-(1-hydroxy-12-octyl-9-oxo-3-aza-10-oxaicos-3-yl)butanoate;2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate
CBNumber:
CB413312659
Molecular Formula:
C40H79NO5
Molecular Weight:
654.06
MDL Number:
MOL File:
2761458-86-8.mol
Last updated:2025-08-21 11:10:20
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2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Properties

Boiling point 687.4±45.0 °C(Predicted)
Density 0.933±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
solubility Ethanol: 5 mg/ml
pka 14.75±0.10(Predicted)

2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Chemical Properties,Uses,Production

Description

YK-009 is an ionizable cationic lipid (pKa = 6.512) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).1 Administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant mRNA in YK-009-containing LNPs induces the production of IgG that binds to the SARS-CoV-2 receptor-binding domain (RBD) in mice, with a boost in IgG titers 10 days after a second dose.WARNING This product is not for human or veterinary use.

References

[1] JINRONG LONG. Novel Ionizable Lipid Nanoparticles for SARS-CoV-2 Omicron mRNA Delivery[J]. Advanced Healthcare Materials, 2023, 12 13. DOI: 10.1002/adhm.202202590

2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Preparation Products And Raw materials

Raw materials

Preparation Products

2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Suppliers

Global( 11)Suppliers
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Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		+8618235132063 sales@tihondan.com China 3767 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3783 58
DC Chemicals 021-8447131 13564518121 doncunbiosci@gmail.com China 545 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62320 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 13854185395; info@easycdmo.com China 10030 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3001 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 31138 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
Beijing Xiecheng Biotechnology Co., Ltd. 18301438069 CHINA 153 58
Supplier Advantage
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		58
SuZhou Medinoah Co.,LTD. 58
DC Chemicals 58
Bide Pharmatech Ltd. 58
Shanghai Easy CDMO Co.,Ltd 58
Abosyn 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Cayman Chemical Company 58
Beijing Xiecheng Biotechnology Co., Ltd. 58
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate YK009 decyl 4-(1-hydroxy-12-octyl-9-oxo-3-aza-10-oxaicos-3-yl)butanoate 2761458-86-8