LY 43578
- CAS No.
- 26766-35-8
- Chemical Name:
- LY 43578
- Synonyms
- LY 43578;Pioglitazone Impurity 36;Bis(4-chlorophenyl)(pyrimidin-5-yl)methanol;α,α-Bis(4-chlorophenyl)pyrimidine-5-methanol;Bis(4-chlorophenyl)(pyrimidine-5-yl)methanol;5-Pyrimidinemethanol, α,α-bis(4-chlorophenyl)-;Bis(4-chlorophenyl)(pyrimidin-5-yl)methanol , LY43578
- CBNumber:
- CB41335680
- Molecular Formula:
- C17H12Cl2N2O
- Molecular Weight:
- 331.2
- MDL Number:
- MFCD30558653
- MOL File:
- 26766-35-8.mol
LY 43578 Chemical Properties,Uses,Production
Description
LY 43578 is an aromatase inhibitor.
Uses
LY43578 is an orally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study[1][2].
References
[1] Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604. DOI:10.1016/0272-0590(87)90144-8
[2] Gonzalez MI, et al. Injection of an aromatase inhibitor after the critical period of sexual differentiation. Pharmacol Biochem Behav. 1994;47(1):183-186. DOI:10.1016/0091-3057(94)90129-5
LY 43578 Preparation Products And Raw materials
Raw materials
Preparation Products
LY 43578 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ:65489617 15618227136 | Sales@ATKchemical.com | China | 9198 | 58 |
| Wuxi Donghe Pharmaceutical Technology Co., Ltd. | 63313187 15358055255 | 63313187@qq.com | China | 1985 | 58 |
| Zhengzhou convergence chemical co., LTD | 0371-0371-55153829 18003835034 | 2853979819@qq.com | China | 9996 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59936 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| Shanghai He-H Chemical Technology Co., Ltd | 18621911604 | 987025641@qq.com | China | 1098 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |





