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2-phenyl-1,2-benzisothiazol-3-(2H)-one

2-phenyl-1,2-benzisothiazol-3-(2H)-one structure

CAS No.: 2527-03-9

Chemical Name:: 2-phenyl-1,2-benzisothiazol-3-(2H)-one

Synonyms: PZ-25;Ebsulfur;PD086291;RP-62373;2-phenyl-1,2-benzothiazol-3-one;2-Phenyl-1-thia-2-azaindan-3-one;2-phenylbenzo[d]isothiazol-3(2H)-one;2-phenyl-1,2-benzisothiazol-3-(2H)-one;1,2-Benzisothiazol-3(2H)-one, 2-phenyl-;2-Phenylbenzo[d]isothiazol-3(2H)-one , RP 62373

CBNumber:: CB41363812

Molecular Formula:: C13H9NOS

Molecular Weight:: 227.28

MDL Number:

MOL File:: 2527-03-9.mol

MSDS File:: SDS

Last updated:2026-05-28 02:59:10

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2-phenyl-1,2-benzisothiazol-3-(2H)-one Properties

Melting point	139-140 °C(Solv: ethanol (64-17-5))
Boiling point	388.9±25.0 °C(Predicted)
Density	1.338±0.06 g/cm3(Predicted)
pka	-0.55±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H315-H302-H335
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

2-phenyl-1,2-benzisothiazol-3-(2H)-one price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0095397	Ebsulfur ≥98%	2527-03-9	100mg	$130	2026-06-04	Buy
ChemScene	CS-0095397	Ebsulfur ≥98%	2527-03-9	250mg	$218	2026-06-04	Buy
ChemScene	CS-0095397	Ebsulfur ≥98%	2527-03-9	1g	$582	2026-06-04	Buy
aablocks	AA00BVBO	2-Phenylbenzo[d]isothiazol-3(2H)-one ≥98%	2527-03-9	25mg	$45	2026-05-28	Buy
aablocks	AA00BVBO	2-Phenylbenzo[d]isothiazol-3(2H)-one ≥98%	2527-03-9	100mg	$142	2026-05-28	Buy

Product number	Packaging	Price	Buy
CS-0095397	100mg	$130	Buy
CS-0095397	250mg	$218	Buy
CS-0095397	1g	$582	Buy
AA00BVBO	25mg	$45	Buy
AA00BVBO	100mg	$142	Buy

2-phenyl-1,2-benzisothiazol-3-(2H)-one Chemical Properties, Uses, Production

Uses

Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase (TryR) of Trypanosoma brucei, with IC50 values of 61-293 nM for Trypanosoma brucei. Ebsulfur can be used for the research of African trypanosomiasis[1].

References

[1] Lu J, et al. Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei. J Biol Chem. 2013 Sep 20;288(38):27456-27468. DOI:10.1074/jbc.M113.495101

2-phenyl-1,2-benzisothiazol-3-(2H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

2-phenyl-1,2-benzisothiazol-3-(2H)-one Suppliers

Global Suppliers ( 21)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Beijing Ditai Pharmaceutical Technology Co., Ltd.	010-13810111756 13810111756	1601345388@qq.com	China	300	58
Tianjin Nuokang Pharmaceutical Technology Co., Ltd.	022-23989838 13810451150	44766350@qq.com	China	2727	58
Cato Research Chemicals Inc.	+86-020-81960175-877 4000-868-328;4000-868-328	tianwen.zhan@cato-chem.com	United States	10384	58
Shanghai Zhikai Pharmaceutical Technology Co., Ltd.	15000251104	kkpp1986@163.com	China	281	58
Shanghai Ruipu Medical Technology Co., Ltd	15895968936	1018762393@qq.com	China	9992	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58
Shanghai Haohong Scientific Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	39718	58
Henan Dowon Chemical Technology Co., Ltd.	16696119288	779113375@qq.com	China	7401	58

Supplier	Advantage
Shanghai YuanYe Biotechnology Co., Ltd.	60
Amadis Chemical Company Limited	58
Beijing Ditai Pharmaceutical Technology Co., Ltd.	58
Tianjin Nuokang Pharmaceutical Technology Co., Ltd.	58
Cato Research Chemicals Inc.	58
Shanghai Zhikai Pharmaceutical Technology Co., Ltd.	58
Shanghai Ruipu Medical Technology Co., Ltd	58
Bide Pharmatech Ltd.	58
Shanghai Haohong Scientific Co., Ltd.	58
Henan Dowon Chemical Technology Co., Ltd.	58

2527-03-9 (2-phenyl-1,2-benzisothiazol-3-(2H)-one) Related Search:

1,2-Benzisothiazol-3(2H)-one, 2-[4-(dimethylamino)phenyl]- 2-(3-chloro-4-fluorophenyl)-2,3-dihydro-1,2-benzothiazol-3-one ethyl 4-(3-oxobenzo[d]isothiazol-2(3H)-yl)benzoate Benzenesulfonamide, N,N-diethyl-3-(3-oxo-1,2-benzisothiazol-2(3H)-yl)- TRIACSIN C

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2-phenyl-1,2-benzisothiazol-3-(2H)-one 2-phenylbenzo[d]isothiazol-3(2H)-one 2-phenyl-1,2-benzothiazol-3-one 2-Phenyl-1-thia-2-azaindan-3-one 2-Phenyl-2,3-dihydro-1,2-benzoisothiazole-3-one PZ-25 RP-62373 1,2-Benzisothiazol-3(2H)-one, 2-phenyl- PD086291 2-Phenylbenzo[d]isothiazol-3(2H)-one , RP 62373 Ebsulfur 2527-03-9