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mycotrienin II

mycotrienin II Structure
mycotrienin II structure
CAS No.
82189-04-6
Chemical Name:
mycotrienin II
Synonyms
mycotrienin II;T 23II, Mycotrienin II, T 23II;20,23-Didehydro-20,23-dideoxo-20,23-dihydroxyansatrienol A 11-[(R)-2-(cyclohexylcarbonylamino)propanoate];D-Alanine, N-(cyclohexylcarbonyl)-, (5R,6E,8E,10E,13S,14R,15R,16Z)-15,22,24-trihydroxy-5-methoxy-14,16-dimethyl-3-oxo-2-azabicyclo[18.3.1]tetracosa-1(24),6,8,10,16,20,22-heptaen-13-yl ester
CBNumber:
CB41375521
Molecular Formula:
C36H50N2O8
Molecular Weight:
638.79
MDL Number:
MOL File:
82189-04-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 18:07:46
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mycotrienin II Properties

storage temp. -20°C
solubility Soluble in DMSO, DMF, Ethanol or Methanol
form solid
color Pale-yellow
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, ethanol, or methanol may be stored at -20°C for up to 3 months.

mycotrienin II price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21996 Ansatrienin B ≥95% 82189-04-6 1mg $389 2026-04-30 Buy
Cayman Chemical 21996 Ansatrienin B ≥95% 82189-04-6 5mg $1502 2026-04-30 Buy
Usbiological 441601 Ansatrienin B 82189-04-6 1mg $679 2026-06-03 Buy
Usbiological A2296-74A Ansatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II) >95%byHPLC| 82189-04-6 1mg $704 2026-06-03 Buy
Usbiological 441601 Ansatrienin B 82189-04-6 2.5mg $1394 2026-06-03 Buy
Product number Packaging Price Buy
21996 1mg $389 Buy
21996 5mg $1502 Buy
441601 1mg $679 Buy
A2296-74A 1mg $704 Buy
441601 2.5mg $1394 Buy

mycotrienin II Chemical Properties, Uses, Production

Description

Ansatrienin b (82189-04-6) represents a novel class of ansamycins.1 Inhibits osteoclastic bone resorption.2 Potentiates the activity of several clinically useful antitumor agents.3 Translation inhibitor which prevents ICAM-1 expression induced by pro-inflammatory cytokines.4

Uses

Ansatrienin B, also known as Mycotrienin II and Antibiotic T 23II, was isolated from a Streptomyces sp.. Closely related to the cytotrienins and trienomycins, it displays potent activity against tumour cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.

in vivo

Ansatrienin B (intraperitoneal injection; once daily; 6 days) is against P-388 -injected mouse tumor growth. The LD50 value in mice of MTN-II is 80 mg/kg in CDF1 male mice[2].

References

[1] M SUGITA. Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II.[J]. Journal of Antibiotics, 1982, 35 11: 1467-1473. DOI:10.7164/antibiotics.35.1467
[2] D FEUERBACH. Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption.[J]. The Journal of Biological Chemistry, 1995, 270 43: 25949-25955. DOI:10.1074/jbc.270.43.25949
[3] YURIKO YAMADA. Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines[J]. Journal of Antibiotics, 2011, 64 5: 361-366. DOI:10.1038/ja.2011.23

mycotrienin II Preparation Products And Raw materials

Raw materials

Preparation Products

mycotrienin II Suppliers

Global Suppliers ( 25)
Supplier Tel Email Country ProdList Advantage
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4578 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4372 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Supplier Advantage
Lynnchem 58
Novachemistry 58
Shanghai Hongye Biotechnology Co. Ltd 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
BOC Sciences 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Zhejiang Huida Biotech Co., LTD 58
Energy Chemical 58

View Latest Price from mycotrienin II manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ansatrienin B pictures 2026-07-16 Ansatrienin B
82189-04-6
 $883.00 10g TargetMol Chemicals Inc.
Ansatrienin B pictures 2025-12-22 Ansatrienin B
82189-04-6
 $1280.00 10g TargetMol Chemicals Inc.

82189-04-6 (mycotrienin II) Related Search:

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mycotrienin II 20,23-Didehydro-20,23-dideoxo-20,23-dihydroxyansatrienol A 11-[(R)-2-(cyclohexylcarbonylamino)propanoate] T 23II, Mycotrienin II, T 23II D-Alanine, N-(cyclohexylcarbonyl)-, (5R,6E,8E,10E,13S,14R,15R,16Z)-15,22,24-trihydroxy-5-methoxy-14,16-dimethyl-3-oxo-2-azabicyclo[18.3.1]tetracosa-1(24),6,8,10,16,20,22-heptaen-13-yl ester 82189-04-6