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Nur77 modulator 3

Nur77 modulator 3 structure

CAS No.: 2097787-75-0

Chemical Name:: Nur77 modulator 3

Synonyms: Nur77 modulator 3;Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)-

CBNumber:: CB413887766

Molecular Formula:: C17H16N4S

Molecular Weight:: 308.4

MDL Number:

MOL File:: 2097787-75-0.mol

MSDS File:: SDS

Last updated:2025-05-19 13:47:26

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Nur77 modulator 3 Properties

Melting point	195-197 °C
Boiling point	510.286±52.00 °C(Press: 760.00 Torr)(predicted)
Density	1.247±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	10.891±0.70(predicted)
form	Solid
color	White to off-white

Nur77 modulator 3 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0955480	Nur77 modulator 3 99.01%	2097787-75-0	5mg	$49	2026-06-04	Buy
ChemScene	CS-0955480	Nur77 modulator 3 99.01%	2097787-75-0	10mg	$76	2026-06-04	Buy
ChemScene	CS-0955480	Nur77 modulator 3 99.01%	2097787-75-0	25mg	$152	2026-06-04	Buy
ChemScene	CS-0955480	Nur77 modulator 3 99.01%	2097787-75-0	50mg	$244	2026-06-04	Buy
ChemScene	CS-0955480	Nur77 modulator 3 99.01%	2097787-75-0	100mg	$390	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0955480	5mg	$49	Buy
CS-0955480	10mg	$76	Buy
CS-0955480	25mg	$152	Buy
CS-0955480	50mg	$244	Buy
CS-0955480	100mg	$390	Buy

Nur77 modulator 3 Chemical Properties, Uses, Production

Uses

Nur77 modulator 3 (9e) can bind to Nur77 and inhibit TGF-β1-induced α-SMA and COLA1 expression in a Nur77-dependent manner. Nur77 modulator 3 induces Nur77 expression and enhances autophagic flux by inhibiting the mTORC1 signaling pathway in vitro and in vivo. Nur77 modulator 3 blocks the progression of hepatic fibrosis[1].

References

[1] Lin G, et al. Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents. Bioorg Chem. 2023 Dec 16;143:107022. DOI:10.1016/j.bioorg.2023.107022

Nur77 modulator 3 Preparation Products And Raw materials

Raw materials

Preparation Products

Nur77 modulator 3 Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2994	55
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9729	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Shaoguan Qicheng Biotechnology Co., Ltd	18122215013	780229652@qq.com	China	1392	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32997	60

Supplier	Advantage
Shanghai Beckham Medical Technology Co., Ltd	55
Shanghai Chaolan Chemical Technology Center	58
TargetMol Chemicals Inc.	58
Shaoguan Qicheng Biotechnology Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60

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Nur77 modulator 3 Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- 2097787-75-0