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2-Bromo-5-chloro-3-fluoropyridine

2-Bromo-5-chloro-3-fluoropyridine Structure
2-Bromo-5-chloro-3-fluoropyridine structure
CAS No.
514797-97-8
Chemical Name:
2-Bromo-5-chloro-3-fluoropyridine
Synonyms
2-Bromo-3-fluoro-5-chloropyridine;2-Bromo-5-chloro-3-fluoropyridine;Pyridine, 2-bromo-5-chloro-3-fluoro-;2-Bromo-5-chloro-3-fluoropyridine ISO 9001：2015 REACH
CBNumber:
CB41459618
Molecular Formula:
C5H2BrClFN
Molecular Weight:
210.43
MDL Number:
MFCD11044268
MOL File:
514797-97-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:09:13
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2-Bromo-5-chloro-3-fluoropyridine Properties

Boiling point 190.8±35.0 °C(Predicted)
Density 1.829±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -3.92±0.20(Predicted)
form solid
color White to off-white
InChI InChI=1S/C5H2BrClFN/c6-5-4(8)1-3(7)2-9-5/h1-2H
InChIKey PYDGFYYLQFJQBZ-UHFFFAOYSA-N
SMILES C1(Br)=NC=C(Cl)C=C1F

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P260-P271-P280
RIDADR  UN2811
HS Code  2933399990

2-Bromo-5-chloro-3-fluoropyridine price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC5924 2-Bromo-5-chloro-3-fluoropyridine ≥95% 514797-97-8 1g $21 2026-06-04 Buy
Apolloscientific PC5924 2-Bromo-5-chloro-3-fluoropyridine ≥95% 514797-97-8 5g $44 2026-06-04 Buy
Activate Scientific AS1846 2-Bromo-5-chloro-3-fluoropyridine 98% 514797-97-8 5g $22 2026-06-04 Buy
Activate Scientific AS1846 2-Bromo-5-chloro-3-fluoropyridine 98% 514797-97-8 25g $62 2026-06-04 Buy
Activate Scientific AS1846 2-Bromo-5-chloro-3-fluoropyridine 98% 514797-97-8 100g $180 2026-06-04 Buy
Product number Packaging Price Buy
PC5924 1g $21 Buy
PC5924 5g $44 Buy
AS1846 5g $22 Buy
AS1846 25g $62 Buy
AS1846 100g $180 Buy

2-Bromo-5-chloro-3-fluoropyridine Chemical Properties,Uses,Production

Synthesis

2-Amino-5-chloro-3-fluoropyridine

246847-98-3

2-Bromo-5-chloro-3-fluoropyridine

514797-97-8

Step 1: 2-Amino-3-fluoro-5-chloropyridine (5.0 g, 34 mmol) was slowly added to 48% hydrobromic acid (HBr) solution (20 mL) at 0°C with stirring. Bromine (Br2, 5.24 mL, 102.3 mmol) was then added dropwise to the resulting mixture over 20 min at 0 °C. The reaction mixture was cooled to -10°C. A solution of sodium nitrite (NaNO2, 5.88 g, 85.3 mmol) in water (20 mL) was slowly added to the mixture over a period of 1.5 h and the mixture continued to be stirred for 30 min. Subsequently, a solution of sodium hydroxide (NaOH, 12 g, 306 mmol) in water (20 mL) was added over 30 minutes and the mixture was gradually warmed to room temperature. After completion of the reaction, the mixture was extracted with ether (3 x 100 mL). The combined organic phases were washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated to give the title compound 2-bromo-5-chloro-3-fluoropyridine as a pale yellow solid (6.43 g, 90% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.23 (d, J = 2.1 Hz, 1H), 7.48 (dd, J = 7.1,2.1 Hz, 1H).

References

[1] Patent: WO2015/187845, 2015, A1. Location in patent: Paragraph 0218
[2] Patent: WO2016/44323, 2016, A1. Location in patent: Paragraph 0323

2-Bromo-5-chloro-3-fluoropyridine synthesis

246847-98-3
514797-97-8
Synthesis of 2-Bromo-5-chloro-3-fluoropyridine from 2-Amino-5-chloro-3-fluoropyridine

2-Bromo-5-chloro-3-fluoropyridine Preparation Products And Raw materials

Raw materials

2-Bromo-5-chloro-3-fluoro-4-iodopyridine 2-Bromo-5-chloro-3-fluoro-6-iodo-pyridine 5-Chloro-2,3-difluoropyridine 2(1H)-Pyridinone,5-chloro-3-fluoro-(9CI) 2-Amino-5-chloro-3-fluoropyridine

Preparation Products

2-Bromo-5-chloro-3-fluoropyridine Suppliers

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Nanjing Lynsci Chemical Co., Ltd +86-025-83208253 +86-13851694729 layefe@163.com China 234 62
China Langchem Inc. 0086-21-58956006 China 7798 57
Nanjing Chemrui Pharmtech Co., Ltd. 86-25-58849758 13851795789 sales@chemrui.com China 47 62
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60
Changzhou Huanling Chemical Co., Ltd. 68
Accela ChemBio Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
Nanjing Lynsci Chemical Co., Ltd 62
China Langchem Inc. 57
Nanjing Chemrui Pharmtech Co., Ltd. 62

View Lastest Price from 2-Bromo-5-chloro-3-fluoropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-chloro-3-fluoropyridine pictures 2026-08-20 2-Bromo-5-chloro-3-fluoropyridine
514797-97-8
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Bromo-5-chloro-3-fluoropyridine pictures 2020-01-08 2-Bromo-5-chloro-3-fluoropyridine
514797-97-8
 $2.00 1KG 99 100kg Career Henan Chemical Co

2-Bromo-5-chloro-3-fluoropyridine Spectrum

2-Bromo-5-chloro-3-fluoropyridine(514797-97-8)1HNMR

514797-97-8(2-Bromo-5-chloro-3-fluoropyridine)Related Search:

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2-Bromo-5-chloro-3-fluoropyridine 2-Bromo-3-fluoro-5-chloropyridine Pyridine, 2-bromo-5-chloro-3-fluoro- 2-Bromo-5-chloro-3-fluoropyridine ISO 9001：2015 REACH 514797-97-8 Halides Heterocycles