Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Structure
Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester structure
CAS No.
842136-32-7
Chemical Name:
Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester
Synonyms
Methyl 5-bromo-2-(trifluoromethyl);Methyl 5-broMo-2-(trifluoroMethyl)benzoate;Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester
CBNumber:
CB02550040
Molecular Formula:
C9H6BrF3O2
Molecular Weight:
283.04
MDL Number:
MFCD14697999
MOL File:
842136-32-7.mol
MSDS File:
SDS
Last updated:2026-05-27 23:07:22
Request For Quotation

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Properties

Boiling point 280.9±40.0 °C(Predicted)
Density 1.598±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form liquid
color Clear, faint to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2916310090

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC500761 Methyl 5-bromo-2-(trifluoromethyl)benzoate 95% 842136-32-7 250mg $89 2026-06-04 Buy
Apolloscientific PC500761 Methyl 5-bromo-2-(trifluoromethyl)benzoate 95% 842136-32-7 1g $137 2026-06-04 Buy
Apolloscientific PC500761 Methyl 5-bromo-2-(trifluoromethyl)benzoate 95% 842136-32-7 5g $398 2026-06-04 Buy
Synthonix M69623 Methyl 5-bromo-2-(trifluoromethyl)benzoate >98% 842136-32-7 250mg $60 2026-05-06 Buy
Synthonix M69623 Methyl 5-bromo-2-(trifluoromethyl)benzoate >98% 842136-32-7 1g $130 2026-05-06 Buy
Product number Packaging Price Buy
PC500761 250mg $89 Buy
PC500761 1g $137 Buy
PC500761 5g $398 Buy
M69623 250mg $60 Buy
M69623 1g $130 Buy

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Chemical Properties, Uses, Production

Synthesis

Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate

680-15-9

METHYL 5-BROMO-2-IODOBENZOATE

181765-86-6

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester

842136-32-7

A. Synthesis of methyl 5-bromo-2-(trifluoromethyl)benzoate. Methyl 5-bromo-2-iodobenzoate (4.65 g, 13.64 mmol) and methyl fluorosulfonyl difluoroacetate (2.6 mL, 20.44 mmol) were dissolved in N-methyl-2-pyrrolidone (10 mL) under nitrogen protection. Copper (I) bromide (235 mg, 1.638 mmol) was subsequently added. The reaction mixture was transferred to a sealed tube and the reaction was stirred at 120 °C for 15 hours. After completion of the reaction, the mixture was cooled to room temperature, diluted with ethyl acetate and washed with saturated aqueous sodium chloride solution. The aqueous phase was back-extracted with ethyl acetate (3 x 25 mL), the organic phases were combined and dried over anhydrous magnesium sulfate. After filtration, the solvent was removed by concentration under reduced pressure. The residue was purified by silica gel column chromatography with hexane solution of 1-5% ethyl acetate as eluent to afford methyl 5-bromo-2-trifluoromethylbenzoate as a colorless oil (2.9 g, 10.25 mmol, 75% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.08 (s, 1H), 8.01 (d, J = 8.20 Hz, 1H), 7.83 (d, J = 8.20 Hz, 1H), 3.90 (s, 3H).

References

[1] Patent: WO2009/89042, 2009, A1. Location in patent: Page/Page column 101

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Preparation Products And Raw materials

Raw materials

Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate 2-(Fluorosulfonyl)difluoroacetic acid Methyl 5-bromo-2-iodobenzoate Cuprous bromide N-Methyl-2-pyrrolidone

Preparation Products

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Suppliers

Global Suppliers ( 41)
Supplier Tel Email Country ProdList Advantage
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9510 58
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Changzhou Anxuan Chemical, Co., Ltd. 13912302692 sales@anxuanchem.com China 4824 58
Chengdu DingDang Pharmaceutical Co., Ltd. 028-86040038 market@dingdangchem.com China 1853 55
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310 526763801@qq.com China 7982 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 6736 58
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15390 58
Shandong utilizing biological technology co., LTD 18669728830 15966937598 3407650895@qq.com China 5165 58
Supplier Advantage
Shanghai Topbiochem Technology Co., Ltd 58
Cochemical Ltd. 58
Changzhou Anxuan Chemical, Co., Ltd. 58
Chengdu DingDang Pharmaceutical Co., Ltd. 55
Shanghai Haozhixiang Biotechnology Co., Ltd 55
Amadis Chemical Company Limited 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58
Cochemical Ltd. 58
Aikon International Limited 58
Shandong utilizing biological technology co., LTD 58

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Spectrum

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester(842136-32-7)1HNMR

842136-32-7 (Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester) Related Search:

2,4-Difluoro-5-iodo-pyridine 3-Chloro-4-(trifluoromethyl)pyridine 2,4-dibroMo-5-fluoropyridine 2-broMo-6-fluoro-3-Methylpyridine 4-Iodo-2-(trifluoromethyl)pyridine
2-Bromo-5-chloro-3-fluoropyridine 2,4,6-trichloronicotinonitrile 2,5-Dichloro-4-iodopyridine 5-bromo-2-fluoro-4-methoxypyridine

1of2

Benzoic acid,5-broMo-2-(trifluoroMethyl)-,Methyl ester Methyl 5-broMo-2-(trifluoroMethyl)benzoate Methyl 5-bromo-2-(trifluoromethyl) 842136-32-7