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H-D-Phe-Pip-Arg-pNA acetate

H-D-Phe-Pip-Arg-pNA acetate structure

CAS No.: 115388-96-0

Chemical Name:: H-D-Phe-Pip-Arg-pNA acetate

Synonyms: S 2238;S2238;S-2238 acetate;D-PHE-PIP-ARG-PNA;Chromogenix S-2765;D-PHE-PIP-ARG-PNA·2HCl;S-2238(Thrombin Substrate);N-α-Z-D-Arg-Gly-Arg-p·2HCl;H-D-Phe-Pip-Arg-pNA acetate;N-α-Z-D-Arg-Gly-Arg-pNA·2HCl;D-Phe-Pip-Arg-pNA (Pippipecolyl)

CBNumber:: CB4148388

Molecular Formula:: C29H40N8O7

Molecular Weight:: 612.69

MDL Number:: MFCD00083792

MOL File:: 115388-96-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

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H-D-Phe-Pip-Arg-pNA acetate Properties

storage temp.	−20°C
form	Solid
color	White to yellow
InChIKey	YVHLNJUMPNYROS-IAYLHCNXNA-N
SMILES	C(=O)(O)C.C([C@@H]1CCCCN1C(=O)[C@H](N)CC1C=CC=CC=1)(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1C=CC(N(=O)=O)=CC=1 \|&1:5,13,24,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS07
Signal word	Warning
Hazard statements	H319-H312-H315-H332-H335-H302-H361
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501
Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38-63
Safety Statements	26-36/37-45-36/37/39-22
WGK Germany	3

H-D-Phe-Pip-Arg-pNA acetate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	QEA38896	H-D-Phe-pip-Arg-pna acetate	115388-96-0	0.1g	$454.3	2026-06-04	Buy
Biosynth	QEA38896	H-D-Phe-pip-Arg-pna acetate	115388-96-0	0.5g	$973.5	2026-06-04	Buy
Biosynth	QEA38896	H-D-Phe-pip-Arg-pna acetate	115388-96-0	1g	$1298	2026-06-04	Buy
Biosynth	QEA38896	H-D-Phe-pip-Arg-pna acetate	115388-96-0	5g	$2596	2026-06-04	Buy
ChemScene	CS-0136435	H-D-Phe-Pip-Arg-pNA acetate 99.81%	115388-96-0	5mg	$260	2026-06-04	Buy

Product number	Packaging	Price	Buy
QEA38896	0.1g	$454.3	Buy
QEA38896	0.5g	$973.5	Buy
QEA38896	1g	$1298	Buy
QEA38896	5g	$2596	Buy
CS-0136435	5mg	$260	Buy

H-D-Phe-Pip-Arg-pNA acetate Chemical Properties, Uses, Production

Uses

H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform[1][2].

References

[1] Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. DOI:10.1093/ajcp/73.5.639
[2] Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353. PMID:6531759

H-D-Phe-Pip-Arg-pNA acetate Preparation Products And Raw materials

Raw materials

Preparation Products

H-D-Phe-Pip-Arg-pNA acetate Suppliers

Global Suppliers ( 84)

Supplier	Tel	Email	Country	ProdList	Advantage
Hzymes Biotechnology Co. LTD	400-8085320 16621234168	hhxm-info@hzymes.com	China	28	58
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	7236	62
Hygeia (Chengdu) pharmaceutical technique Co., Ltd	028-84502008 13568869383	sales@hygeiapharm.com	China	291	55
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15775	55
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58

Supplier	Advantage
Hzymes Biotechnology Co. LTD	58
Chemsky（shanghai）International Co.,Ltd.	50
Hunan Hui Bai Shi Biotechnology Co., Ltd.	62
Hygeia (Chengdu) pharmaceutical technique Co., Ltd	55
Quality Control Solutions Ltd.	56
Shanghai Macklin Biochemical Co.,Ltd.	55
Shanghai YuanYe Biotechnology Co., Ltd.	60
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58

View Latest Price from H-D-Phe-Pip-Arg-pNA acetate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-15	H-D-Phe-Pip-Arg-pNA acetate 115388-96-0			98.86%	10g	TargetMol Chemicals Inc.

H-D-Phe-Pip-Arg-pNA acetate
115388-96-0
$0.00
98.86%
TargetMol Chemicals Inc.

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1of4

D-PHE-PIP-ARG-PNA D-PHE-L-PIPECOLYL-ARG P-NITROANILIDE*TRI ACETATE D-Phe-Pip-Arg-pNA (Pippipecolyl) H-D-Phe-Pip-Arg-pNA · 2 acetate, H-D-Phe-L-pipecolyl-Arg-pNA · 2 acetate D-Phe-L-pipecolyl-Arg-p-nitroanilide dihydrochloride S-2765,Chromogenic Substrate for Fxa S-2238(Thrombin Substrate) Chromogenix S-2765 D-PHE-PIP-ARG-PNA·2HCl S 2238;S-2238;D-PHE-PIP-ARG-PNA·2HCL S 2238;S2238 Factor Xa Chromogenic Substrate 1 H-D-Phe-Pip-Arg-pNA acetate L-Argininamide-D-phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitrophenyl) Acetic Acid N-α-Z-D-Arg-Gly-Arg-pNA·2HCl L-Argininamide,D-phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitrophenyl)-,triacetate S-2238 acetate N-α-Z-D-Arg-Gly-Arg-p·2HCl (S)-1-(D-Phenylalanyl)-N-((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)piperidine-2-carboxamide acetate 115388-96-0 C27H36N8O5 C27H38N8O5Cl2