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Dimethyl-SGD-1882

Dimethyl-SGD-1882 structure

CAS No.: 3026416-27-0

Chemical Name:: Dimethyl-SGD-1882

Synonyms: Dimethyl-SGD-1882

CBNumber:: CB414907812

Molecular Formula:: C44H43N5O7

Molecular Weight:: 753.84

MDL Number:

MOL File:: 3026416-27-0.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:16

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Dimethyl-SGD-1882 Properties

Boiling point	963.815±65.00 °C(Press: 760.00 Torr)(predicted)
Density	1.318±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	5.069±0.10(predicted)

Dimethyl-SGD-1882 Chemical Properties, Uses, Production

Uses

Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication[1].

IC 50

Pyrrolobenzodiazepines

References

[1] Mantaj J, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs). Angew Chem Int Ed Engl. 2017 Jan 9;56(2):462-488. DOI:10.1002/anie.201510610

Dimethyl-SGD-1882 Preparation Products And Raw materials

Raw materials

Preparation Products

Dimethyl-SGD-1882 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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Dimethyl-SGD-1882 3026416-27-0