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PNPLA3 degrader-1

PNPLA3 degrader-1 structure

CAS No.: 3036158-98-9

Chemical Name:: PNPLA3 degrader-1

Synonyms: PF-07853578;1-Piperidinecarboxylic acid, 3,3-difluoro-5-[(5R)-5-methyl-1,1-dioxido-2-isothiazolidinyl]-, 4-chlorophenyl ester, (5R)-;PNPLA3 degrader-1;Uricase, Microorganism

CBNumber:: CB414907847

Molecular Formula:: C16H19ClF2N2O4S

Molecular Weight:: 408.85

MDL Number:

MOL File:: 3036158-98-9.mol

MSDS File:: SDS

Last updated:2026-05-28 01:28:13

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PNPLA3 degrader-1 Properties

Boiling point	515.020±60.00 °C(Press: 760.00 Torr)(predicted)
Density	1.490±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	-3.945±0.60(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

PNPLA3 degrader-1 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-1181228	PF-07853578 99.08%	3036158-98-9	5mg	$677	2026-06-04	Buy
ChemScene	CS-1181228	PF-07853578 99.08%	3036158-98-9	10mg	$1083	2026-06-04	Buy
ChemScene	CS-1181228	PF-07853578 99.08%	3036158-98-9	25mg	$2167	2026-06-04	Buy
ChemScene	CS-1181228	PF-07853578 99.08%	3036158-98-9	50mg	$3467	2026-06-04	Buy
ChemScene	CS-1181228	PF-07853578 99.08%	3036158-98-9	100mg	$5633	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-1181228	5mg	$677	Buy
CS-1181228	10mg	$1083	Buy
CS-1181228	25mg	$2167	Buy
CS-1181228	50mg	$3467	Buy
CS-1181228	100mg	$5633	Buy

PNPLA3 degrader-1 Chemical Properties, Uses, Production

Uses

PF-07853578 (Example 11) is a PNPLA3 degrader with an EC50 of 8 nM. PNPLA3 degrader-1 can be used in the study of cirrhosis and hepatocellular carcinoma[1].

References

[1] Christopher William Am Ende, et al. Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifiers. WO, WO2024084360A1. 2024-04-25

PNPLA3 degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

PNPLA3 degrader-1 Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	17702719238	sales@sun-shinechem.com	China	1197	64
Chengdu PEIP Pharmaceutical Technology Co., LTD.	028-61715638 18011352545	1242335275@qq.com	China	473	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5985	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Guangzhou Ruidi Biotechnology Co., Ltd.	020-82099279 18988941402	sales@ubiochem.com	China	9998	58

Supplier	Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	64
Chengdu PEIP Pharmaceutical Technology Co., LTD.	58
Nantong QuanYi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Guangzhou Ruidi Biotechnology Co., Ltd.	58

3036158-98-9 (PNPLA3 degrader-1) Related Search:

PNPLA3 modifier 1 Anti-cancer compound library NUV-244 Clinical Compound Library

PNPLA3 degrader-1 1-Piperidinecarboxylic acid, 3,3-difluoro-5-[(5R)-5-methyl-1,1-dioxido-2-isothiazolidinyl]-, 4-chlorophenyl ester, (5R)- PF-07853578 Uricase, Microorganism 3036158-98-9