3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER
- CAS No.
- 34529-06-1
- Chemical Name:
- 3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER
- Synonyms
- dimethyl 3-aminophthalate;MFCD16293748;Apster Impurity 75.;Sitagliptin Impurity 37-d3;dimethyl 3-aminobenzene-1,2-dioate;3-Amino-phthalic acid dimethyl ester;dimethyl 3-aminobenzene-1,2-dicarboxylate;DiMethyl 3-aMino-1,2-benzenedicarboxylate;3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER;Methyl 3-amino-2-(methoxycarbonyl)benzoate
- CBNumber:
- CB41502628
- Molecular Formula:
- C10H11NO4
- Molecular Weight:
- 209.2
- MDL Number:
- MFCD09029586
- MOL File:
- 34529-06-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | D11283 | 1g | $34 |
| Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | D11283 | 5g | $40 |
| Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | D11283 | 10g | $60 |
| Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | D11283 | 25g | $120 |
| Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | D11283 | 50g | $240 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H315-H319 |
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405 |
| HS Code | 2921420090 |
3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | D11283 | Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | 34529-06-1 | 1g | $34 | 2026-05-06 | Buy |
| Synthonix | D11283 | Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | 34529-06-1 | 5g | $40 | 2026-05-06 | Buy |
| Synthonix | D11283 | Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | 34529-06-1 | 10g | $60 | 2026-05-06 | Buy |
| Synthonix | D11283 | Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | 34529-06-1 | 25g | $120 | 2026-05-06 | Buy |
| Synthonix | D11283 | Dimethyl 3-amino-1,2-benzenedicarboxylate 97.0% | 34529-06-1 | 50g | $240 | 2026-05-06 | Buy |
3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER Chemical Properties,Uses,Production
Uses
Dimethyl 3-aminophthalate is a useful research chemical.
Synthesis
13365-26-9
34529-06-1
The general procedure for the synthesis of dimethyl 3-amino-phthalate from methyl 3-nitrophthalate was as follows: first, methyl 3-nitrophthalate was converted to the corresponding chloride by a chlorination reaction, followed by esterification to obtain dimethyl 3-nitrophthalate (100% yield). Next, the nitro group was reduced to an amino group by catalytic hydrogenation to obtain dimethyl 3-amino-phthalate (100% yield). Subsequently, diazotization of the amino group was followed by iodination to obtain dimethyl 3-iodophthalate (about 91% yield). Then, a saponification reaction was carried out on dimethyl 3-iodophthalate, followed by acidification to obtain 3-iodophthalic acid (yield about 93%). Finally, 3-iodophthalic acid was oxidized and reacted in the presence of KBrO3 and 0.73 M H2SO4 at 55-60 °C for 12 h to obtain water-soluble MIBX.Upon completion of the reaction, purification by evaporation, cooled milling and filtration yielded white solid MIBX (~70% yield, melting point 258-260 °C). The conversion of the process is nearly quantitative and can be monitored by 1H NMR spectroscopy.The physical properties of MIBX include IR (KBr) showing characteristic absorption peaks; 1H NMR (D2O, 300 MHz) and 13C NMR (D2O, 75 MHz) showing specific chemical shifts.
References
[1] Journal of Heterocyclic Chemistry, 1989, vol. 26, # 6, p. 1885 - 1886
[2] Tetrahedron Letters, 2002, vol. 43, # 4, p. 569 - 572
[3] Patent: US2004/30187, 2004, A1. Location in patent: Page 2; Sheet 1
[4] RSC Advances, 2015, vol. 5, # 60, p. 48861 - 48867
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 1, p. 285 - 288
3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8742 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 17259 | 58 |
| Asia Chem I and E (Jiangsu) Co Ltd | +8615105181882 | mera.z@nitrobenzenechemical.com | China | 139 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
View Lastest Price from 3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-29 | Dimethyl 3-aminophthalate
34529-06-1
|
$139.50 | 25Kg/Drum | 98.00%HPLC | 5tons/month | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2020-01-05 | 3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER
34529-06-1
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- Dimethyl 3-aminophthalate
34529-06-1
- $139.50
- 98.00%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
-
- 3-AMINO-1,2-PHTHALIC ACID, DIMETHYL ESTER
34529-06-1
- $1.00
- 95-99%
- Career Henan Chemical Co
