Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Ethyl 4-nitro-L-phenylalanine

Ethyl 4-nitro-L-phenylalanine

Ethyl 4-nitro-L-phenylalanine Structure
Ethyl 4-nitro-L-phenylalanine structure
CAS No.
34276-53-4
Chemical Name:
Ethyl 4-nitro-L-phenylalanine
Synonyms
4-NO2-Phe-Oet;4-NO2-Phe-Oet-OH;Ethyl 4-nitro-L-phenylalanine;Ethyl 4-nitro-L-phenylalanine,95%;p-Nitro-L-phenylalanine ethyl ester;L-Phenylalanine, 4-nitro-, ethyl ester;ETHYL 4-NITRO-L-PHENYLALANINE USP/EP/BP;(S)-Ethyl 2-amino-3-(4-nitrophenyl)propanoate
CBNumber:
CB41519488
Molecular Formula:
C11H14N2O4
Molecular Weight:
238.24
MDL Number:
MFCD09878820
MOL File:
34276-53-4.mol
Last updated:2026-09-12 18:52:26
Request For Quotation

Ethyl 4-nitro-L-phenylalanine Properties

Boiling point 372.1±27.0 °C(Predicted)
Density 1.246±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka 6.62±0.33(Predicted)
Appearance Yellow to orange Solid
optical activity Consistent with structure

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Ethyl 4-nitro-L-phenylalanine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 60896 ETHYL 4-NITRO-L-PHENYLALANINE 97% 34276-53-4 1G $62 2026-04-30 Buy
AstaTech 60896 ETHYL 4-NITRO-L-PHENYLALANINE 97% 34276-53-4 5G $186 2026-04-30 Buy
aablocks AA00BZP9 Ethyl 4-Nitro-L-Phenylalanine 95% 34276-53-4 250mg $27 2026-05-28 Buy
aablocks AA00BZP9 Ethyl 4-Nitro-L-Phenylalanine 95% 34276-53-4 1g $36 2026-05-28 Buy
aablocks AA00BZP9 Ethyl 4-Nitro-L-Phenylalanine 95% 34276-53-4 5g $75 2026-05-28 Buy
Product number Packaging Price Buy
60896 1G $62 Buy
60896 5G $186 Buy
AA00BZP9 250mg $27 Buy
AA00BZP9 1g $36 Buy
AA00BZP9 5g $75 Buy

Ethyl 4-nitro-L-phenylalanine Chemical Properties,Uses,Production

Synthesis

H-4-NITRO-PHE-OET HCL

58816-66-3

ETHYL 4-NITRO-L-PHENYLALANINE

34276-53-4

GENERAL STEPS: To a stirred mixed solution of ethyl (S)-2-amino-3-(4-nitrophenyl)propanoate hydrochloride (23.0 g, CAS No. 58816-66-3) in dichloromethane (230 mL) and water (230 mL) was slowly added 46-48% sodium hydroxide solution (7.7 g, 1.1 eq.). The organic and aqueous layers were separated and the aqueous phase was extracted with dichloromethane (100 mL). The combined dichloromethane layers were washed sequentially with water (100 mL) and saturated brine (100 mL). The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give ethyl (S)-2-amino-3-(4-nitrophenyl)propionate in quantitative yield. The resulting free nitro ester was dissolved in fresh dichloromethane (120 mL), spiro[3,5]nonane-1,3-dione (12.9 g, CAS No. 455264-97-8) [Ref: Wasserman, H.H. et al., J. Org. Chem., 38, 1451-1455 (1973)] was added, and the reaction was stirred. After 16 h, the completion of the reaction was confirmed by HPLC monitoring. The reaction mixture was diluted with dichloromethane (120 mL), washed sequentially with 11% sodium bicarbonate solution (100 mL), saturated brine (100 mL) and then dried over anhydrous magnesium sulfate. After removing the solvent under reduced pressure, ethyl (S)-2-amino-3-(4-nitrophenyl)propionate was obtained in quantitative yield (32.4 g as a slowly crystallizing viscous oil; melting point 120 °C). NMR hydrogen spectrum (DMSO-d6) δ: 8.39 (1H, d), 8.17 (2H, d), 7.56 (2H, d), 4.33 (1H, s), 4.31 (1H, m), 4.14 (2H, q), 3.29 (1H, dd), 3.15 (1H, dd), 1.43-1.70 (8H, m), 1.30 (1H , m), 1.15 (3H, t + 1H, m). Mass spectrum (ESI+) m/z: 373.3 [M+H]+.

References

[1] Patent: WO2004/7428, 2004, A1. Location in patent: Page 45
[2] Patent: WO2004/7428, 2004, A1. Location in patent: Page 47
[3] Patent: WO2004/7428, 2004, A1. Location in patent: Page 45-46

Ethyl 4-nitro-L-phenylalanine Preparation Products And Raw materials

Raw materials

H-4-Nitro-Phe-OEt HCl Sodium hydroxide Dichloromethane Water

Preparation Products

Ethyl 4-nitro-L-phenylalanine Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
The future of Shanghai Industrial Co., Ltd. 021-61552785 sales@shshiji.com China 9531 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai JONLN Reagent Co., Ltd. 400-0066400 13621662912 422131432@qq.com China 9970 55
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
Hotechem Shanghai Co., Ltd., 021-34621078 13120882795 465106944@qq.com China 859 56
SanoChem (Chengdu) Tech. Co., Ltd. 28-87999436 02887999436 sales@sano-chem.com China 3792 55
Supplier Advantage
Shanghai Hanhong Scientific Co.,Ltd. 64
Hangzhou Sage Chemical Co., Ltd. 58
Nanjing Norris-Pharm Technology Co., Ltd 55
The future of Shanghai Industrial Co., Ltd. 55
SynAsst Chemical. 55
Shanghai JONLN Reagent Co., Ltd. 55
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Finetech Industry Limited 58
Hotechem Shanghai Co., Ltd., 56
SanoChem (Chengdu) Tech. Co., Ltd. 55

View Lastest Price from Ethyl 4-nitro-L-phenylalanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-NO2-Phe-Oet pictures 2026-09-11 4-NO2-Phe-Oet
34276-53-4
 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
ETHYL 4-NITRO-L-PHENYLALANINE pictures 2024-08-27 ETHYL 4-NITRO-L-PHENYLALANINE
34276-53-4
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

Ethyl 4-nitro-L-phenylalanine Spectrum

ETHYL 4-NITRO-L-PHENYLALANINE(34276-53-4)1HNMR

34276-53-4(Ethyl 4-nitro-L-phenylalanine)Related Search:

4-Nitro-phenylalanine methyl ester N-Boc-4-nitro-L-phenylalanine-t-butyl ester H-4-Nitro-Phe-OEt HCl Ethyl 4-nitro-L-phenylalanine 4-Nitro-L-phenylalanine tert-butyl ester hydrochloride
L-Phenylalanine, 4-nitro-, ethyl ester p-Nitro-L-phenylalanine ethyl ester (S)-Ethyl 2-amino-3-(4-nitrophenyl)propanoate 4-NO2-Phe-Oet ETHYL 4-NITRO-L-PHENYLALANINE USP/EP/BP Ethyl 4-nitro-L-phenylalanine,95% 4-NO2-Phe-Oet-OH Ethyl 4-nitro-L-phenylalanine 34276-53-4