3-Bromo-2-iodo-thiophene
- CAS No.
- 60404-24-2
- Chemical Name:
- 3-Bromo-2-iodo-thiophene
- Synonyms
- TH-I-Br;3-Bromo-2-iodo-thiophene;Thiophene, 3-bromo-2-iodo-;3-Bromo-2-iodothiophene 95+%
- CBNumber:
- CB41558751
- Molecular Formula:
- C4H2BrIS
- Molecular Weight:
- 288.93
- MDL Number:
- MFCD11848091
- MOL File:
- 60404-24-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2934999090 |
3-Bromo-2-iodo-thiophene price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | KCA40424 | 3-bromo-2-iodothiophene | 60404-24-2 | 1g | $318.6 | 2026-06-04 | Buy |
| Biosynth | KCA40424 | 3-bromo-2-iodothiophene | 60404-24-2 | 10g | $2006 | 2026-06-04 | Buy |
| Apolloscientific | OR43638 | 3-Bromo-2-iodothiophene 97% | 60404-24-2 | 100mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR43638 | 3-Bromo-2-iodothiophene 97% | 60404-24-2 | 250mg | $37 | 2026-06-04 | Buy |
| Apolloscientific | OR43638 | 3-Bromo-2-iodothiophene 97% | 60404-24-2 | 1g | $139 | 2026-06-04 | Buy |
3-Bromo-2-iodo-thiophene Chemical Properties, Uses, Production
Synthesis
872-31-1
60404-24-2
General procedure for the synthesis of 3-bromo-2-iodothiophene from 3-bromothiophene: In a 100 ml four-necked flask, 3-bromothiophene (10 g, 61.3 mmol), iodine (5.61 g, 22.1 mmol), iodic acid (2.27 g, 12.9 mmol), acetic acid (20 ml), cyclohexane (30 ml), water (8 ml) and concentrated sulfuric acid (0.4 mL). The reaction mixture was stirred at 40°C for 17 hours. After completion of the reaction, the mixture was cooled to room temperature and then extracted by adding saturated aqueous sodium bicarbonate (40 mL) and diethyl ether (30 mL). The organic phase was washed sequentially with aqueous sodium hydroxide-sodium sulfite solution (30 mL) and saturated sodium chloride solution (30 mL) for 10 min each. The washed organic phase was dried with magnesium sulfate, filtered and concentrated. The crude product obtained was purified by distillation under reduced pressure (about 125 °C/9 torr) to give 3-bromo-2-iodothiophene (15.6 g, 88% yield) as an almost colorless liquid.
References
[1] Patent: JP6007631, 2016, B2. Location in patent: Paragraph 0032
[2] Synthesis (Germany), 2015, vol. 47, # 24, p. 3901 - 3906
[3] Organic Letters, 2013, vol. 15, # 18, p. 4666 - 4669
[4] Patent: KR2017/26286, 2017, A. Location in patent: Paragraph 0105-0109
3-Bromo-2-iodo-thiophene Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
3-Bromo-2-iodo-thiophene Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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