1-(4-Bromo-2-thienyl)ethan-1-one
- CAS No.
- 7209-11-2
- Chemical Name:
- 1-(4-Bromo-2-thienyl)ethan-1-one
- Synonyms
- 1-(4-Bromothiophen-2-yl)ethan-1-one;AKOS B020506;BUTTPARK 95\04-34;ART-CHEM-BB B020506;2-ACETYL-4-BROMOTHIOPHENE;4-Bromo-2-acetylthiophene;1-(4-Bromothien-2-yl)ethanone;2-Acetyl-4-bromothiophene 97%;1-(4-Bromo-2-Thienyl)Ethanone;4-bromo-2-acetylthiophene 
- CBNumber:
- CB3132568
- Molecular Formula:
- C6H5BrOS
- Molecular Weight:
- 205.07
- MDL Number:
- MFCD01566552
- MOL File:
- 7209-11-2.mol
- MSDS File:
- SDS
| Boiling point | 66-67°C 0,2mm |
|---|---|
| Density | 1.619±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| Appearance | Colorless to light yellow Liquid |
| CAS DataBase Reference | 7209-11-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-36-22 |
| Safety Statements | 26-36/37/39 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
1-(4-Bromo-2-thienyl)ethan-1-one price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0033728 | 1-(4-Bromothiophen-2-yl)ethanone ≥97% | 7209-11-2 | 5g | $12 | 2026-06-04 | Buy |
| ChemScene | CS-0033728 | 1-(4-Bromothiophen-2-yl)ethanone ≥97% | 7209-11-2 | 10g | $20 | 2026-06-04 | Buy |
| ChemScene | CS-0033728 | 1-(4-Bromothiophen-2-yl)ethanone ≥97% | 7209-11-2 | 15g | $32 | 2026-06-04 | Buy |
| ChemScene | CS-0033728 | 1-(4-Bromothiophen-2-yl)ethanone ≥97% | 7209-11-2 | 25g | $49 | 2026-06-04 | Buy |
| ChemScene | CS-0033728 | 1-(4-Bromothiophen-2-yl)ethanone ≥97% | 7209-11-2 | 100g | $195 | 2026-06-04 | Buy |
1-(4-Bromo-2-thienyl)ethan-1-one Chemical Properties,Uses,Production
Chemical Properties
Yellow liquid
Synthesis
88-15-3
7209-11-2
General procedure for the synthesis of 4-bromo-2-acetylthiophene from 2-acetylthiophene: In a 250 mL single-necked round-bottomed flask, 2-acetylthiophene (3.00 g, 23.81 mmol), anhydrous aluminum chloride (9.53 g, 71.43 mmol), and carbon tetrachloride (80 mL) were added, and the mixture was cooled to -40 °C. After 10 min, a slow dropwise addition of bromine ( 3.81 g, 23.81 mmol) in carbon tetrachloride (20 mL) was added slowly and stirred at room temperature for 0.5 h after completion of the addition. After 12 hours of reaction, TLC monitoring showed complete consumption of the feedstock. The reaction mixture was carefully poured into a mixture of saturated sodium hydroxide solution and crushed ice and extracted with ethyl acetate (75 mL x 3). The organic phases were combined, washed twice with saturated brine and dried over anhydrous magnesium sulfate. Purification by column chromatography (petroleum ether:ethyl acetate = 500:1) gave a pale yellow oily liquid product (2.74 g) in 72.6% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 15, p. 4037 - 4043
[2] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 713 - 716
[3] Patent: CN103408540, 2016, B. Location in patent: Paragraph 0096; 0126; 0127
[4] Chemistry of Heterocyclic Compounds, 2013, vol. 49, # 3, p. 386 - 391
[5] Khim. Geterotsikl. Soedin., 2013, # 3, p. 416 - 422
1-(4-Bromo-2-thienyl)ethan-1-one Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3990 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
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