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1-(4-Bromo-2-thienyl)ethan-1-one

CAS No.
7209-11-2
Chemical Name:
1-(4-Bromo-2-thienyl)ethan-1-one
Synonyms
1-(4-Bromothiophen-2-yl)ethan-1-one;AKOS B020506;BUTTPARK 95\04-34;ART-CHEM-BB B020506;2-ACETYL-4-BROMOTHIOPHENE;4-Bromo-2-acetylthiophene;1-(4-Bromothien-2-yl)ethanone;2-Acetyl-4-bromothiophene 97%;1-(4-Bromo-2-Thienyl)Ethanone;4-bromo-2-acetylthiophene 
CBNumber:
CB3132568
Molecular Formula:
C6H5BrOS
Molecular Weight:
205.07
MDL Number:
MFCD01566552
MOL File:
7209-11-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:33

1-(4-Bromo-2-thienyl)ethan-1-one Properties

Boiling point 66-67°C 0,2mm
Density 1.619±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
Appearance Colorless to light yellow Liquid
CAS DataBase Reference 7209-11-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-36-22
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  29339900

1-(4-Bromo-2-thienyl)ethan-1-one price More Price(67)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0033728 1-(4-Bromothiophen-2-yl)ethanone ≥97% 7209-11-2 5g $12 2026-06-04 Buy
ChemScene CS-0033728 1-(4-Bromothiophen-2-yl)ethanone ≥97% 7209-11-2 10g $20 2026-06-04 Buy
ChemScene CS-0033728 1-(4-Bromothiophen-2-yl)ethanone ≥97% 7209-11-2 15g $32 2026-06-04 Buy
ChemScene CS-0033728 1-(4-Bromothiophen-2-yl)ethanone ≥97% 7209-11-2 25g $49 2026-06-04 Buy
ChemScene CS-0033728 1-(4-Bromothiophen-2-yl)ethanone ≥97% 7209-11-2 100g $195 2026-06-04 Buy
Product number Packaging Price Buy
CS-0033728 5g $12 Buy
CS-0033728 10g $20 Buy
CS-0033728 15g $32 Buy
CS-0033728 25g $49 Buy
CS-0033728 100g $195 Buy

1-(4-Bromo-2-thienyl)ethan-1-one Chemical Properties,Uses,Production

Chemical Properties

Yellow liquid

Synthesis

2-Acetylthiophene

88-15-3

1-(4-BROMO-2-THIENYL)ETHAN-1-ONE

7209-11-2

General procedure for the synthesis of 4-bromo-2-acetylthiophene from 2-acetylthiophene: In a 250 mL single-necked round-bottomed flask, 2-acetylthiophene (3.00 g, 23.81 mmol), anhydrous aluminum chloride (9.53 g, 71.43 mmol), and carbon tetrachloride (80 mL) were added, and the mixture was cooled to -40 °C. After 10 min, a slow dropwise addition of bromine ( 3.81 g, 23.81 mmol) in carbon tetrachloride (20 mL) was added slowly and stirred at room temperature for 0.5 h after completion of the addition. After 12 hours of reaction, TLC monitoring showed complete consumption of the feedstock. The reaction mixture was carefully poured into a mixture of saturated sodium hydroxide solution and crushed ice and extracted with ethyl acetate (75 mL x 3). The organic phases were combined, washed twice with saturated brine and dried over anhydrous magnesium sulfate. Purification by column chromatography (petroleum ether:ethyl acetate = 500:1) gave a pale yellow oily liquid product (2.74 g) in 72.6% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 15, p. 4037 - 4043
[2] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 713 - 716
[3] Patent: CN103408540, 2016, B. Location in patent: Paragraph 0096; 0126; 0127
[4] Chemistry of Heterocyclic Compounds, 2013, vol. 49, # 3, p. 386 - 391
[5] Khim. Geterotsikl. Soedin., 2013, # 3, p. 416 - 422

88-15-3
7209-11-2
Synthesis of 1-(4-Bromo-2-thienyl)ethan-1-one from 2-Acetylthiophene
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1-(4-BROMO-2-THIENYL)-1-ETHANONE 2-ACETYL-4-BROMOTHIOPHENE AKOS B020506 BUTTPARK 95\04-34 ART-CHEM-BB B020506 1-(4-Bromo-2-thienyl)ethan-1-one, tech 1-(4-Bromo-2-thienyl)ethan-1-one ,97% 1-(4-Bromothien-2-yl)ethanone 4-Bromo-2-acetylthiophene 2-Acetyl-4-bromothiophene 97% 4-bromo-2-acetylthiophene  1-(4-bromothiophen-2-yl)ethanone 1-(4-Bromo-2-Thienyl)Ethanone 1-(4-Bromothien-2-yl)ethan-1-one, 2-Ethanoyl-4-bromothiophene Ethanone, 1-(4-bromo-2-thienyl)- 1-(4-Bromothiophen-2-yl)ethan-1-one 1-(4-Bromo-2-thienyl)ethan-1-one 7209-11-2 7209-11-0 KETONE