ChemicalBook >> CAS DataBase List >>3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester

3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester

CAS No.
121912-29-6
Chemical Name:
3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester
Synonyms
Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate;Ethyl 1-(4-pyridinyl)-4-piperidinecarboxylate;Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate;1-pyridin-4-yl-4-piperidinecarboxylic acid ethyl ester;4-Piperidinecarboxylic acid, 1-(4-pyridinyl)-, ethyl ester;3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester
CBNumber:
CB4164285
Molecular Formula:
C13H18N2O2
Molecular Weight:
234.29
MDL Number:
MFCD04115024
MOL File:
121912-29-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:28

3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester Properties

Boiling point 356.4±32.0 °C(Predicted)
Density 1.120±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 10.88±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H227
Precautionary statements  P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235

3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 132521 Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate 121912-29-6 5.00g $1404 2026-05-18 Buy
Matrix Scientific 132521 Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate 121912-29-6 10.00g $1800 2026-05-18 Buy
Synthonix E57076 Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate 97% 121912-29-6 100mg $80 2026-05-06 Buy
Synthonix E57076 Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate 97% 121912-29-6 250mg $240 2026-05-06 Buy
Synthonix E57076 Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate 97% 121912-29-6 1g $960 2026-05-06 Buy
Product number Packaging Price Buy
132521 5.00g $1404 Buy
132521 10.00g $1800 Buy
E57076 100mg $80 Buy
E57076 250mg $240 Buy
E57076 1g $960 Buy

3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester Chemical Properties,Uses,Production

Synthesis

Ethanol

64-17-5

1-(PYRIDIN-4-YL)-PIPERIDINE-4-CARBOXYLIC ACID

93913-86-1

3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-CARBOXYLIC ACID ETHYL ESTER

121912-29-6

Example 2 Difluorotriacetate of [1-(pyridin-4-yl)piperidin-4-yl]methyl 2-[amino(imino)methyl]-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid; Step 1 Synthesis of ethyl 1-(pyridin-4-yl)piperidin-4- carboxylate; To a 1-(pyridin-4-yl)piperidin-4-carboxylic acid (20.0 g, 97.0 mmol) ethanol (480 mL) suspension of thionyl chloride (7.1 mL, 97.0 mmol) was added dropwise and the mixture was stirred at 50°C overnight. After completion of the reaction, the solvent was removed by evaporation under reduced pressure and the resulting residue was diluted with dichloromethane, washed sequentially with 1N aqueous sodium hydroxide and saturated aqueous ammonium chloride, the organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate, which did not require further purification. Yield: 21.0 g (89.7 mmol, 93%). MS (ESI, m/z): 235 [M + H]+. 1H-NMR (CDCl3) δ: 1.26 (t, 3H), 1.72-1.86 (m, 2H), 1.97-2.05 (m, 2H), 2.49-2.58 (m, 1H), 2.93-3.02 (m , 2H), 3.82-3.02 (m, 2H). , 2H), 3.82 (dt, 2H), 4.16 (q, 2H), 6.66 (dd, 2H), 8.25 (dd, 2H).

References

[1] Patent: EP2311810, 2011, A1. Location in patent: Page/Page column 21
[2] Tetrahedron, 1988, vol. 44, # 23, p. 7095 - 7108

3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 40)Suppliers
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Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
JW & Y Pharmlab Co., Ltd. 021-64340559 xinyu_shi@jwypharmlab.com.cn China 11999 58
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Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
3A Chemicals 400-668-9898 service@3achem.com China 20535 58
Shanghai Baoyisheng Biotechnology Co., LTD 15221020695 ; 502277408@qq.com China 456 58
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19765 58

View Lastest Price from 3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate pictures 2026-07-10 Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate
121912-29-6
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
4-Piperidinecarboxylic acid, 1-(4-pyridinyl)-, ethyl ester Ethyl 1-(pyridin-4-yl)piperidine-4-carboxylate 1-pyridin-4-yl-4-piperidinecarboxylic acid ethyl ester Ethyl 1-(4-pyridinyl)-4-piperidinecarboxylate Ethyl 1-(4-pyridinyl)piperidine-4-carboxylate 3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid ethyl ester 121912-29-6