Ribostamycin sulfate
- CAS No.
- 53797-35-6
- Chemical Name:
- Ribostamycin sulfate
- Synonyms
- Ibistacin;ribostamin;ribomycine;landamycine;Mandamycine;Ribostamycin s;Ribomycin sulfate;riboflavinesulfate;Vistamycin sulfate;Ribostamycinsulfat
- CBNumber:
- CB4165752
- Molecular Formula:
- C17H36N4O14S
- Molecular Weight:
- 552.55
- MDL Number:
- MFCD23380549
- MOL File:
- 53797-35-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 175-180 C |
|---|---|
| alpha | D20 +39° (c = 1) |
| Flash point | >110°(230°F) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | powder |
| color | White to Off-White |
| Water Solubility | Soluble in water |
| Merck | 14,8206 |
| Stability | Hygroscopic |
| InChIKey | RTCDDYYZMGGHOE-CARKYZAMNA-N |
| SMILES | OS(O)(=O)=O.NC[C@@H]1O[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O)[C@@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@@H](N)[C@H](O)[C@H]1O |
| FDA UNII | QFN1QU7PEN |
| UNSPSC Code | 51281664 |
| NACRES | NA.85 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H312+H332-H360 | |||||||||
| Precautionary statements | P201-P202-P280-P302+P352+P312-P304+P340+P312-P308+P313 | |||||||||
| PPE | Eyeshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 61-20/21/22-36/38 | |||||||||
| Safety Statements | 53-22-36/37/39-45-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WK2300000 | |||||||||
| HS Code | 2941.90.1010 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Repr. 1B |
|||||||||
| Toxicity | LD50 i.v. in mice: 225 mg/kg (Shomura) | |||||||||
| NFPA 704 |
|
Ribostamycin sulfate price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R2255 | Ribostamycin sulfate salt | 53797-35-6 | 1g | $1060 | 2023-06-20 | Buy |
| Sigma-Aldrich | R2255 | Ribostamycin sulfate salt | 53797-35-6 | 250mg | $341 | 2023-01-07 | Buy |
| TCI Chemical | R0194 | Ribostamycin Sulfate >90.0%(N) | 53797-35-6 | 1g | $438 | 2026-04-30 | Buy |
| TRC | TRC-R417700-50MG | Ribostamycin Sulfate >95%(HPLC) | 50mg | $146 | 2026-06-03 | Buy | |
| TRC | TRC-R417700-250MG | Ribostamycin Sulfate >95%(HPLC) | 250mg | $209 | 2026-06-03 | Buy |
Ribostamycin sulfate Chemical Properties, Uses, Production
Uses
Antibacterial;Ribosomal protein synthesis inhibitor
Uses
Ribostamycin is a broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus. It is used in pharmacokinetic and nephrotoxicity studies.
Definition
ChEBI: An aminoglycoside sulfate salt resulting from the reaction of ribostamycin with sulfuric acid.
Biological Activity
Aminoglycosides, such as ribostamycin, bind to the bacterial 30S and 50S ribosomal subunit, which inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. This causes misreading of mRNA which makes bacteria unable to make essential proteins. It also inhibits the chaperone activity of protein disulfide isomerase (PDI).
Synthesis
Preparation of high-purity ribostamycin sulfate:
1. The resolving solution is acidified and diluted.
2. Loaded onto an ion-exchange column, washed with water.
3. Eluted with ammonia, collecting fractions before optical rotation reaches "0".
4. The eluate is concentrated by nanofiltration and then by steam thin-film evaporation.
5. The concentrate is treated with charcoal and spray-dried.
Ribostamycin sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuxi Fortune Pharmaceutical Co., Ltd. | -- | sales@wuxifortune.com.cn | China | 13 | 58 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Wuhan Fortuna Chemical Co., Ltd | 027-59207852 13308628970 | buy@fortunachem.com | China | 2696 | 58 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| Shanghai Ruji Biology Technology Co., Ltd. | +86-21-65211385-8001 36031160 | sales@shruji.com | China | 3223 | 55 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
View Latest Price from Ribostamycin sulfate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | Ribostamycin sulfate
53797-35-6
|
$38.00-81.00 | 99.72% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-15 | Ribostamycin sulfate
53797-35-6
|
$38.00-81.00 | 99.72% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | Ribostamycin sulfate
53797-35-6
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Ribostamycin sulfate
53797-35-6
- $38.00-81.00
- 99.72%
- TargetMol Chemicals Inc.
-
- Ribostamycin sulfate
53797-35-6
- $38.00-81.00
- 99.72%
- TargetMol Chemicals Inc.
-
- Ribostamycin sulfate
53797-35-6
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
