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MASTOPARAN X

CAS No.
72093-22-2
Chemical Name:
MASTOPARAN X
Synonyms
MP-X;MASTOPARAN X;INWKGIAAMAKKLL-NH2;ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2;H-ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2;L-Leucinamide, L-isoleucyl-L-asparaginyl-L-tryptophyl-L-lysylglycyl-L-isoleucyl-L-alanyl-L-alanyl-L-methionyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-
CBNumber:
CB4170149
Molecular Formula:
C73H126N20O15S
Molecular Weight:
1555.97
MDL Number:
MFCD00076866
MOL File:
72093-22-2.mol
MSDS File:
SDS
Last updated:2025-08-21 11:10:20
Product description Number Pack Size Price
Mastoparan X 255756 1mg $495
Mastoparan X M2417X-01 1mg $531
MASTOPARAN X 95.00% PEP0002443 1MG $597.89
MASTOPARAN X 95.00% PEP0002443 5MG $735.63

MASTOPARAN X Properties

Boiling point 1797.4±65.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. -15°C
solubility DMF: 25 mg/ml
DMSO: 25 mg/ml
Ethanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml
form Lyophilized solid.
pka 13.24±0.46(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
Safety Statements  22-24/25

MASTOPARAN X price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 255756 Mastoparan X 72093-22-2 1mg $495 2021-12-16 Buy
Usbiological M2417X-01 Mastoparan X 72093-22-2 1mg $531 2021-12-16 Buy
American Custom Chemicals Corporation PEP0002443 MASTOPARAN X 95.00% 72093-22-2 1MG $597.89 2021-12-16 Buy
American Custom Chemicals Corporation PEP0002443 MASTOPARAN X 95.00% 72093-22-2 5MG $735.63 2021-12-16 Buy
Product number Packaging Price Buy
255756 1mg $495 Buy
M2417X-01 1mg $531 Buy
PEP0002443 1MG $597.89 Buy
PEP0002443 5MG $735.63 Buy

MASTOPARAN X Chemical Properties,Uses,Production

Uses

Has effects similar to mastoparan; binds with high affinity to calmodulin and inhibits sarcoplasmic reticulum calcium-ATPase

Definition

ChEBI: Mastoparan-V is a member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, tryptophyl, lysyl, glycyl, isoleucyl, alanyl, alanyl, methionyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa velutina and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes. It has a role as an antibacterial agent. It is a member of mastoparans and a peptidyl amide.

References

[1] CHUN-HSIEN LIN . Structural and biological characterization of mastoparans in the venom of Vespa species in Taiwan[J]. Peptides, 2011, 32 10: Pages 2027-2036. DOI: 10.1016/j.peptides.2011.08.015
[2] DEAN A. MALENCIK  Sonia R A. High affinity binding of the mastoparans by calmodulin[J]. Biochemical and biophysical research communications, 1983, 114 1: Pages 50-56. DOI: 10.1016/0006-291x(83)91592-9
[3] T HIGASHIJIMA  E M R  J Burnier. Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.[J]. The Journal of Biological Chemistry, 1990, 265 24: 14176-14186.
[4] ANNIELLE MENDES BRITO DA SILVA. Pro-necrotic Activity of Cationic Mastoparan Peptides in Human Glioblastoma Multiforme Cells Via Membranolytic Action.[J]. Molecular Neurobiology, 2018: 5490-5504. DOI: 10.1007/s12035-017-0782-1
[5] XUEQIN ZHAO. The Antimicrobial Peptide Mastoparan X Protects Against Enterohemorrhagic Escherichia coli O157:H7 Infection, Inhibits Inflammation, and Enhances the Intestinal Epithelial Barrier.[J]. Frontiers in Microbiology, 2021: 644887. DOI: 10.3389/fmicb.2021.644887

MASTOPARAN X Preparation Products And Raw materials

Raw materials

Preparation Products

MASTOPARAN X Suppliers

Global( 107)Suppliers
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Shenzhen Nexconn Pharmatechs Ltd
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Moxin Chemicals
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H-ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2 ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2 INWKGIAAMAKKLL-NH2 MASTOPARAN X MP-X L-Leucinamide, L-isoleucyl-L-asparaginyl-L-tryptophyl-L-lysylglycyl-L-isoleucyl-L-alanyl-L-alanyl-L-methionyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl- 72093-22-2 C73H126N20O15S C73H126N20O15S1 Peptide G-Protein