MASTOPARAN
- CAS No.
- 72093-21-1
- Chemical Name:
- MASTOPARAN
- Synonyms
- MASTOPARAN;NSC 351907;Mastoparan-1;INLKALAALAKKIL;INLKALAALAKKIL-NH2;Mastoparan(acetate);MASTOPARAN USP/EP/BP;MASTOPARAN 4ACOH 6H2O;MASTOPARAN VESPULA LEWISII;Mastoparan from Vespula lewisii
- CBNumber:
- CB4292335
- Molecular Formula:
- C70H131N19O15
- Molecular Weight:
- 1478.91
- MDL Number:
- MFCD00076865
- MOL File:
- 72093-21-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 1676.8±65.0 °C(Predicted) |
|---|---|
| Density | 1.150±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: 1 mg/mL, clear, colorless |
| form | White solid |
| pka | 13.43±0.46(Predicted) |
| color | white |
| biological source | synthetic |
| Water Solubility | water: 5mg/mL |
| BRN | 5491949 |
| Sequence | H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2 |
| InChIKey | MASXKPLGZRMBJF-MVSGICTGSA-N |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H334-H317 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 10 |
| Storage Class | 11 - Combustible Solids |
MASTOPARAN price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M5280 | Mastoparan, Vespula lewisii ≥97% (HPLC), powder | 72093-21-1 | 1mg | $181 | 2026-04-30 | Buy |
| Sigma-Aldrich | 444898 | Mastoparan A cell-permeable synthetic peptide with sequence identical to | 72093-21-1 | 1mg | $216 | 2026-04-30 | Buy |
| Cayman Chemical | 20240 | Mastoparan ≥95% | 72093-21-1 | 500μg | $55 | 2021-12-16 | Buy |
| Cayman Chemical | 20240 | Mastoparan ≥95% | 72093-21-1 | 1mg | $88 | 2021-12-16 | Buy |
| Usbiological | 255755 | Mastoparan Asreported | 72093-21-1 | 1mg | $353 | 2026-06-03 | Buy |
MASTOPARAN Chemical Properties, Uses, Production
Uses
Mastoparan has been used as a calmodulin antagonist.
Definition
ChEBI: A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, leucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, isoleucyl, and leucinamide residues coupled in sequence. It is the majo active component of the venom of the vespid wasp, Vespula lewisii and causes degranulation of mast cells.
General Description
Mastoparan is a cationic, amphiphilic, tetradecapeptide amide. It is composed of the restricted amino acid and the repeated sequence. This protein is a nonspecific secretagogue isolated from venom of wasp.
Biochem/physiol Actions
Mastoparan effectively stimulates exocytosis from diverse mammalian cells. The encoded protein facilitates the secretion of histamine from mast cells, serotonin from platelets, catecholamines from chromaffin cells and prolactin from the anterior pituitary. In addition, it is also involved in activation of Phospholipase A2 and phosphoinositides (Pl) break down. Mastoparan functions as an inhibitor for calmodulin-stimulated phosphodiesterase. Mastoparan helps in mitochondrial permeability transition by enhancing an apparent bimodal mechanism of action.
MASTOPARAN Preparation Products And Raw materials
Raw materials
Preparation Products
MASTOPARAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 1010 | 55 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 |
