3-Bromo-4-fluorotoluene
- CAS No.
- 452-62-0
- Chemical Name:
- 3-Bromo-4-fluorotoluene
- Synonyms
- 2-BROMO-1-FLUORO-4-METHYLBENZENE;3-Bromo-4-fluorotolu;3-Bromo-4-fluotoluene;3-Bromo-4-flurotoluene;3-BROMO-4-FLUOROTOLUENE;3-Bromo-4-fluorotoluene,99%;3-broMo -4-fluorine toluene;3-Bromo-4-fluorotoluene >3-Bromo-4-fluorotoluene 99%;Benzene, 2-bromo-1-fluoro-4-methyl-
- CBNumber:
- CB4171267
- Molecular Formula:
- C7H6BrF
- Molecular Weight:
- 189.02
- MDL Number:
- MFCD00040827
- MOL File:
- 452-62-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 169 °C/756 mmHg (lit.) |
|---|---|
| Density | 1.507 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 164 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid |
| Specific Gravity | 1.52 |
| color | Clear colorless to light yellow |
| BRN | 1680604 |
| InChI | InChI=1S/C7H6BrF/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3 |
| InChIKey | QLRKALMVPCQTMU-UHFFFAOYSA-N |
| SMILES | C1(F)=CC=C(C)C=C1Br |
| CAS DataBase Reference | 452-62-0(CAS DataBase Reference) |
| FDA UNII | SNF4C42NWZ |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Bromo-4-fluorotoluene price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 337013 | 3-Bromo-4-fluorotoluene 99% | 452-62-0 | 5g | $31.2 | 2023-06-20 | Buy |
| TCI Chemical | B1945 | 3-Bromo-4-fluorotoluene >98.0%(GC) | 452-62-0 | 5g | $73 | 2026-04-30 | Buy |
| Biosynth | AAA45262 | 3-Bromo-4-fluorotoluene | 452-62-0 | 0.25g | $250 | 2026-06-04 | Buy |
| Biosynth | AAA45262 | 3-Bromo-4-fluorotoluene | 452-62-0 | 2.5g | $906.25 | 2026-06-04 | Buy |
| Activate Scientific | AS92716 | 3-Bromo-4-fluorotoluene 98% | 452-62-0 | 5g | $20 | 2026-06-04 | Buy |
3-Bromo-4-fluorotoluene Chemical Properties, Uses, Production
Chemical Properties
colorless to light yellow liqui
Uses
3-Bromo-4-fluorotoluene was employed as starting reagent in the synthesis of [4-fluoro-3-(trimethylsilyl)benzyl]guanidine. It was also employed as benzyne precursor in the synthesis of 6-methyl-1,2,3,4-tetrahydro-2,3-(benzylidenedioxy)-1,4-ethenonapthalene.
Synthesis
542-56-3
583-68-6
452-62-0
Example 4: 84 g of 2-bromo-4-methylaniline and 54.5 g of isobutyl nitrite were slowly added dropwise through two dropping funnels, respectively, to a solution of 160 g of dimethoxyethane containing 37 g of boron trifluoride and 10.3 g of hydrogen fluoride at a temperature of -5°C to 0°C (the dropping process lasted for 1 hour). After the dropwise addition, the reaction mixture was continued to be stirred at 0°C for 15 min, followed by diafiltration. The resulting crystalline diazonium salt was washed with 50 mL of pre-cooled dimethoxyethane and then dried under vacuum at room temperature. A diazonium salt product of 122.5 g was obtained in a yield of 86% of the theoretical value. The decomposition reaction was carried out according to the method of Example 6, resulting in 3-bromo-4-fluorotoluene in 92.4% yield of the theoretical value.
References
[1] Patent: US4476320, 1984, A
3-Bromo-4-fluorotoluene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| Hubei Smer Pharmaceutical Technology Co., Ltd. | 15527913960 | 826455094@qq.com | China | 490 | 58 |
| Weifang Weimeng Chemical Co., Ltd. | QQ 1340191485 15105445095 | weimengchem@163.com | China | 482 | 58 |
| Beijing Jinrui Meixiang Technology Co., Ltd | 13691579162 | 480326527@qq.com | China | 498 | 58 |
| Fuxin Yinghui High tech Materials Technology Co., Ltd | 17624188899 | 3799130626@qq.com | China | 199 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from 3-Bromo-4-fluorotoluene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 3-Bromo-4-fluorotoluene
452-62-0
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-28 | 3-Bromo-4-fluorotoluene
452-62-0
|
$10.00 | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | 3-Bromo-4-fluorotoluene
452-62-0
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 3-Bromo-4-fluorotoluene
452-62-0
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-Bromo-4-fluorotoluene
452-62-0
- $10.00
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 3-Bromo-4-fluorotoluene
452-62-0
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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