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3-Bromo-4-fluorotoluene

3-Bromo-4-fluorotoluene Structure
3-Bromo-4-fluorotoluene structure
CAS No.
452-62-0
Chemical Name:
3-Bromo-4-fluorotoluene
Synonyms
2-BROMO-1-FLUORO-4-METHYLBENZENE;3-Bromo-4-fluorotolu;3-Bromo-4-fluotoluene;3-Bromo-4-flurotoluene;3-BROMO-4-FLUOROTOLUENE;3-Bromo-4-fluorotoluene,99%;3-broMo -4-fluorine toluene;3-Bromo-4-fluorotoluene >3-Bromo-4-fluorotoluene 99%;Benzene, 2-bromo-1-fluoro-4-methyl-
CBNumber:
CB4171267
Molecular Formula:
C7H6BrF
Molecular Weight:
189.02
MDL Number:
MFCD00040827
MOL File:
452-62-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:48:53
Product description Number Pack Size Price
3-Bromo-4-fluorotoluene 99% 337013 5g $31.2
3-Bromo-4-fluorotoluene >98.0%(GC) B1945 5g $73
3-Bromo-4-fluorotoluene AAA45262 0.25g $250
3-Bromo-4-fluorotoluene AAA45262 2.5g $906.25
3-Bromo-4-fluorotoluene 98% AS92716 5g $20
More product size
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3-Bromo-4-fluorotoluene Properties

Boiling point 169 °C/756 mmHg (lit.)
Density 1.507 g/mL at 25 °C (lit.)
refractive index n20/D 1.531(lit.)
Flash point 164 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
Specific Gravity 1.52
color Clear colorless to light yellow
BRN 1680604
InChI InChI=1S/C7H6BrF/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3
InChIKey QLRKALMVPCQTMU-UHFFFAOYSA-N
SMILES C1(F)=CC=C(C)C=C1Br
CAS DataBase Reference 452-62-0(CAS DataBase Reference)
FDA UNII SNF4C42NWZ
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29039990
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
2
2 0

3-Bromo-4-fluorotoluene price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 337013 3-Bromo-4-fluorotoluene 99% 452-62-0 5g $31.2 2023-06-20 Buy
TCI Chemical B1945 3-Bromo-4-fluorotoluene >98.0%(GC) 452-62-0 5g $73 2026-04-30 Buy
Biosynth AAA45262 3-Bromo-4-fluorotoluene 452-62-0 0.25g $250 2026-06-04 Buy
Biosynth AAA45262 3-Bromo-4-fluorotoluene 452-62-0 2.5g $906.25 2026-06-04 Buy
Activate Scientific AS92716 3-Bromo-4-fluorotoluene 98% 452-62-0 5g $20 2026-06-04 Buy
Product number Packaging Price Buy
337013 5g $31.2 Buy
B1945 5g $73 Buy
AAA45262 0.25g $250 Buy
AAA45262 2.5g $906.25 Buy
AS92716 5g $20 Buy

3-Bromo-4-fluorotoluene Chemical Properties,Uses,Production

Chemical Properties

colorless to light yellow liqui

Uses

3-Bromo-4-fluorotoluene was employed as starting reagent in the synthesis of [4-fluoro-3-(trimethylsilyl)benzyl]guanidine. It was also employed as benzyne precursor in the synthesis of 6-methyl-1,2,3,4-tetrahydro-2,3-(benzylidenedioxy)-1,4-ethenonapthalene.

Synthesis

Isobutyl nitrite

542-56-3

2-Bromo-4-methylaniline

583-68-6

3-Bromo-4-fluorotoluene

452-62-0

Example 4: 84 g of 2-bromo-4-methylaniline and 54.5 g of isobutyl nitrite were slowly added dropwise through two dropping funnels, respectively, to a solution of 160 g of dimethoxyethane containing 37 g of boron trifluoride and 10.3 g of hydrogen fluoride at a temperature of -5°C to 0°C (the dropping process lasted for 1 hour). After the dropwise addition, the reaction mixture was continued to be stirred at 0°C for 15 min, followed by diafiltration. The resulting crystalline diazonium salt was washed with 50 mL of pre-cooled dimethoxyethane and then dried under vacuum at room temperature. A diazonium salt product of 122.5 g was obtained in a yield of 86% of the theoretical value. The decomposition reaction was carried out according to the method of Example 6, resulting in 3-bromo-4-fluorotoluene in 92.4% yield of the theoretical value.

References

[1] Patent: US4476320, 1984, A

3-Bromo-4-fluorotoluene Preparation Products And Raw materials

Raw materials

Isobutyl nitrite 2-Bromo-4-methylaniline Hydrogen fluoride Boron trifluoride 1,2-Dimethoxyethane

Preparation Products

5-Bromo-4-fluoro-2-iodotoluene 4-BROMO-5-FLUORO-2-METHYLANILINE

3-Bromo-4-fluorotoluene Suppliers

Global( 348)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5220 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58

View Lastest Price from 3-Bromo-4-fluorotoluene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Bromo-4-fluorotoluene pictures 2026-06-30 3-Bromo-4-fluorotoluene
452-62-0
 1KG 99.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
3-Bromo-4-fluorotoluene pictures 2026-05-28 3-Bromo-4-fluorotoluene
452-62-0
 $10.00 1KG 99.% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
3-Bromo-4-fluorotoluene pictures 2026-03-20 3-Bromo-4-fluorotoluene
452-62-0
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd

3-Bromo-4-fluorotoluene Spectrum

3-Bromo-4-fluorotoluene(452-62-0)1HNMR3-Bromo-4-fluorotoluene(452-62-0)FT-IR3-Bromo-4-fluorotoluene(452-62-0)IR

452-62-0(3-Bromo-4-fluorotoluene)Related Search:

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3-Bromo-4-fluorotolu 3-broMo -4-fluorine toluene 3-Bromo-4-flurotoluene 3-BROMO-4-FLUOROTOLUENE 3-Bromo-4-fluotoluene 3-Bromo-4-fluorotoluene,99% Benzene, 2-bromo-1-fluoro-4-methyl- 3-Bromo-4-fluorotoluene 99% 3-Bromo-4-fluorotoluene > 2-BROMO-1-FLUORO-4-METHYLBENZENE 452-62-0 452620-96-0 59907-13-1 ARYL HALIDE Organic Building Blocks Halogenated Hydrocarbons C7 Aryl Building Blocks Fluorobenzene Fluorin-contained toluene series Halogen toluene Miscellaneous Bromine Compounds Fluorine Compounds Aryl C7 Halogenated Hydrocarbons Aromatic Halides (substituted)