4-Formylphenylboronic acid pinacol cyclic ester
- CAS No.
- 128376-64-7
- Chemical Name:
- 4-Formylphenylboronic acid pinacol cyclic ester
- Synonyms
- 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZALDEHYDE;4-FORMYLPHENYLBORONIC ACID, PINACOL ESTER;)-benzaL;AKOS BRN-1133;4-(4,4,5,5-tetramethyL;4-FORMYLPHENYLBORONIC ACID PINACOLATE;4-Formylbenzeneboronic acid, pinacol ester;4-Formylphenylboronic acid picol cyclic ester;4-Formylbenzeneboronic acid, pinacol ester 98%;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-
- CBNumber:
- CB4187848
- Molecular Formula:
- C13H17BO3
- Molecular Weight:
- 232.08
- MDL Number:
- MFCD04972375
- MOL File:
- 128376-64-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 55-58°C |
|---|---|
| Boiling point | 341.3±25.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Crystalline Solid |
| color | Off-white |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C13H17BO3/c1-12(2)13(3,4)17-14(16-12)11-7-5-10(9-15)6-8-11/h5-9H,1-4H3 |
| InChIKey | DMBMXJJGPXADPO-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1 |
| CAS DataBase Reference | 128376-64-7(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-43 | |||||||||
| Safety Statements | 26-36/37/39-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | No | |||||||||
| HS Code | 2931900090 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| Hazard Classifications | Skin Sens. 1 | |||||||||
| NFPA 704 |
|
4-Formylphenylboronic acid pinacol cyclic ester price More Price(78)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | BML00007 | 4-Formylphenylboronic acid, pinacol ester Aldrich | 128376-64-7 | 1g | $62.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | CDS004697 | 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzaldehyde AldrichCPR | 128376-64-7 | 100mg | $68.1 | 2023-01-07 | Buy |
| TCI Chemical | T2923 | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde >97.0%(GC) | 128376-64-7 | 1g | $24 | 2026-04-30 | Buy |
| TCI Chemical | T2923 | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde >97.0%(GC) | 128376-64-7 | 5g | $60 | 2026-04-30 | Buy |
| Biosynth | FF63281 | 4-Formylphenylboronic acid pinacol cyclic ester | 128376-64-7 | 10g | $181.5 | 2026-06-04 | Buy |
4-Formylphenylboronic acid pinacol cyclic ester Chemical Properties, Uses, Production
Uses
A boronic acid benzaldehyde compound for proteomics research.
Synthesis
1122-91-4
73183-34-3
128376-64-7
General procedure for the synthesis of 4-formylphenylboronic acid pinacol ester from p-bromobenzaldehyde and pinacol ester of biboronic acid: to a stirred solution of p-bromobenzaldehyde (8 g, 0.15 mol), pinacol ester of biboronic acid (45.7 g, 0.18 mol), and Pd(dppf)Cl2 (5.26 g, 7.5 mmol) in 1,4-dioxane, under argon protection, was KOAc (22.0 g, 0.225 mol) was added. The reaction mixture was stirred at 80 °C for 15 min. After completion of the reaction, the solvent was removed under reduced pressure. The residue was diluted with petroleum ether (500 mL) and the insoluble material was removed by filtration. The filtrate was concentrated under reduced pressure to give the crude product. The crude product was purified by fast chromatography (silica gel, petroleum ether/ethyl acetate, 10:1) to afford 4-(4,4,5,5-tetramethyl-1,3,2-dioxolan-2-yl)benzaldehyde (32.5 g, 95% yield) as a white solid.
References
[1] Advanced Synthesis and Catalysis, 2016, vol. 358, # 6, p. 977 - 983
[2] Patent: WO2013/170165, 2013, A1. Location in patent: Page/Page column 93
[3] Applied Organometallic Chemistry, 2011, vol. 25, # 7, p. 537 - 541
[4] Organic Letters, 2016, vol. 18, # 20, p. 5248 - 5251
[5] Journal of the American Chemical Society, 2016, vol. 138, # 1, p. 84 - 87
4-Formylphenylboronic acid pinacol cyclic ester Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou SuGuan Chemical Technology Co., Ltd. | 15958048562 | 2032153781@qq.com | China | 463 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Beijing VSciChem Technology Co., Ltd. | 13811761079 | vscichem@163.com | China | 271 | 64 |
View Latest Price from 4-Formylphenylboronic acid pinacol cyclic ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4-Formylphenylboronic acid pinacol cyclic ester
128376-64-7
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2019-09-02 | 4-Formylphenylboronic acid pinacol cyclic ester
128376-64-7
|
$1.00 | 1KG | 98% | 1kg; 2kg；10kg; 100kg | Career Henan Chemical Co |
-
- 4-Formylphenylboronic acid pinacol cyclic ester
128376-64-7
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Formylphenylboronic acid pinacol cyclic ester
128376-64-7
- $1.00
- 98%
- Career Henan Chemical Co
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