4-Dimethylaminobenzoic acid
- CAS No.
- 619-84-1
- Chemical Name:
- 4-Dimethylaminobenzoic acid
- Synonyms
- P-DIMETHYLAMINOBENZOIC ACID;4-Diaminomethylbenzoic acid;LR-78;Solarchem O;AKOS BBS-00003737;RARECHEM AL BO 0056;-Dimethylaminobenzoicacid;4-DIMETHYLAMINOBENZOIC ACID;p-(dimethylamino)-benzoicaci;4-(dimethylamino)-benzoicaci
- CBNumber:
- CB4190291
- Molecular Formula:
- C9H11NO2
- Molecular Weight:
- 165.19
- MDL Number:
- MFCD00002537
- MOL File:
- 619-84-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-(Dimethylamino)benzoic acid 98% | D139459 | 25g | $51.4 |
| 4-Dimethylaminobenzoic Acid >98.0%(HPLC)(T) | D0724 | 25g | $41 |
| 4-Dimethylaminobenzoic Acid >98.0%(HPLC)(T) | D0724 | 500g | $331 |
| 4-Dimethylaminobenzoic acid | 119202 | 100.00g | $74 |
| 4-Dimethylaminobenzoic acid | 119202 | 500.00g | $194 |
| More product size | |||
| Melting point | 241-243 °C (dec.)(lit.) |
|---|---|
| Boiling point | 117-118 C |
| Density | 1,04 g/cm |
| refractive index | 1,3715 |
| Flash point | 170 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 6.03, 11.49(at 25℃) |
| color | White, beige to grayish green |
| Water Solubility | Insoluble in water. |
| Merck | 14,3232 |
| BRN | 386867 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Major Application | peptide synthesis |
| InChI | 1S/C9H11NO2/c1-10(2)8-5-3-7(4-6-8)9(11)12/h3-6H,1-2H3,(H,11,12) |
| InChIKey | YDIYEOMDOWUDTJ-UHFFFAOYSA-N |
| SMILES | CN(C)c1ccc(cc1)C(O)=O |
| CAS DataBase Reference | 619-84-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | D1MA908EV0 |
| NIST Chemistry Reference | Benzoic acid, 4-(dimethylamino)-(619-84-1) |
| EPA Substance Registry System | Benzoic acid, 4-(dimethylamino)- (619-84-1) |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DG8735000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29224995 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
4-Dimethylaminobenzoic acid price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D139459 | 4-(Dimethylamino)benzoic acid 98% | 619-84-1 | 25g | $51.4 | 2026-04-30 | Buy |
| TCI Chemical | D0724 | 4-Dimethylaminobenzoic Acid >98.0%(HPLC)(T) | 619-84-1 | 25g | $41 | 2026-04-30 | Buy |
| TCI Chemical | D0724 | 4-Dimethylaminobenzoic Acid >98.0%(HPLC)(T) | 619-84-1 | 500g | $331 | 2026-04-30 | Buy |
| Matrix Scientific | 119202 | 4-Dimethylaminobenzoic acid | 619-84-1 | 100.00g | $74 | 2026-05-18 | Buy |
| Matrix Scientific | 119202 | 4-Dimethylaminobenzoic acid | 619-84-1 | 500.00g | $194 | 2026-05-18 | Buy |
4-Dimethylaminobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
4-Dimethylaminobenzoic acid is light grey powder
Uses
4-(Dimethylamino)benzoic Acid is a substituted benzoic acid that acts as an inhibitor of ultraviolet mediated damage to skin. 4-(Dimethylamino)benzoic Acid is a biotransformation product of 2-ethylhe xyl 4-(N,N-dimethylamino)benzoate (EDP), a widely used UV filters in sunscreen cosmetics and other cosmetic products.
Uses
4-Dimethylaminobenzoic acid a substituted benzoic acid that acts as an inhibitor of ultraviolet mediated damage to skin. It is a biotransformation product of 2-ethylhexyl 4- (N,N-dimethylaminobenzo)benzoate(EDP), a widely used UV filters in sunscreen cosmetics and other cosmetic products.
Synthesis Reference(s)
The Journal of Organic Chemistry, 25, p. 1807, 1960 DOI: 10.1021/jo01080a035
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
a, weigh 1g of ethyl p-aminobenzoate in a two-port round-bottomed flask, add 40 ml of acetone to dissolve, then add 3.6g of anhydrous potassium carbonate and 14.1g of iodomethane, the reaction under nitrogen protection at 80 stirring reflux for 24 hours, the reaction is complete, filtration of the reaction solution, take the filtrate, extracted with dichloromethane, the organic phase dewatered with magnesium sulfate, filtration and removal of magnesium sulfate, evaporation and concentration of the product with a The product was separated and purified by chromatographic column (mobile phase dichloromethane: methanol = 20:1) to obtain the product ethyl 4-dimethylaminobenzoate.
b, in step a of the proceeds of 4-dimethylaminobenzoic acid ethyl ester, add 10% sodium hydroxide, not more than the reaction can be, 95% ethanol as a solvent, reflux reaction at 85 C for 6 hours, with 1M hydrochloric acid to adjust the PH to a weak acidic reaction, the reaction solution is concentrated, add anhydrous acetone to dissolve, filtration, take the precipitate, vacuum drying to get 4-dimethylaminobenzoic acid;
Purification Methods
Crystallise the acid from EtOH/water. [Beilstein 14 IV 1164.]
4-Dimethylaminobenzoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1319 | 58 |
| Anhui Royal Chemical Co., Ltd. | +86-025-86655873 +86-13962173137 | marketing@royal-chem.com | China | 201 | 55 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20123 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
View Lastest Price from 4-Dimethylaminobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 4-Dimethylaminobenzoic acid
619-84-1
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%min | 500KGS | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-05-28 | 4-DIMETHYLAMINOBENZOIC ACID
619-84-1
|
US $3000.00 / kg | 100kg | 99.4% | 2000 | Anhui Royal Chemical Co., Ltd. | |
 |
2026-03-20 | 4-Dimethylaminobenzoic acid
619-84-1
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 4-Dimethylaminobenzoic acid
619-84-1
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 4-DIMETHYLAMINOBENZOIC ACID
619-84-1
- US $3000.00 / kg
- 99.4%
- Anhui Royal Chemical Co., Ltd.
-
- 4-Dimethylaminobenzoic acid
619-84-1
- US $1.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
