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N,N-Dimethyl-p-toluidine

N,N-Dimethyl-p-toluidine Structure
N,N-Dimethyl-p-toluidine structure
CAS No.
99-97-8
Chemical Name:
N,N-Dimethyl-p-toluidine
Synonyms
N,N,4-Trimethylaniline;Dimethyl-p-toluidine;dimethyltoluidine;N,N-DIMETHYL-4-TOLUIDINE;N,N-DIMETHYL-PARA-TOLUIDINE;N,N-Dialkylarylamine;4-DIMETHYLAMINOTOLUENE;n,n-dimethyl-p-toluidin;N,N-Dimethyl-p-tolylamine;N,N,4-TRIMETHYLBENZENAMINE
CBNumber:
CB4196682
Molecular Formula:
C9H13N
Molecular Weight:
135.21
MDL Number:
MFCD00008316
MOL File:
99-97-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-25 20:17:46
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N,N-Dimethyl-p-toluidine Properties

Melting point -25°C
Boiling point 211 °C(lit.)
Density 0.937 g/mL at 25 °C(lit.)
vapor density >1 (vs air)
vapor pressure 0.1 hPa (20 °C)
refractive index n20/D 1.546(lit.)
Flash point 182 °F
storage temp. Store below +30°C.
solubility 0.65g/l
pka pK1:7.24(+1) (25°C)
form Liquid
color Clear yellow
explosive limit 7%
Water Solubility Miscible with alcohol, ether and chloroform. Immiscible with water.
BRN 774409
Henry's Law Constant 2.0×10-1 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Dielectric constant 3.3(20℃)
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions NAIL SCULPTING
InChI 1S/C9H13N/c1-8-4-6-9(7-5-8)10(2)3/h4-7H,1-3H3
InChIKey GYVGXEWAOAAJEU-UHFFFAOYSA-N
SMILES CN(C)c1ccc(C)cc1
LogP 1.729-2.81 at 35℃
Toxicology and Carcinogenesis Toxicology and Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage Studies)
CAS DataBase Reference 99-97-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII S8XC5939VU
Proposition 65 List N,N-Dimethyl-p-toluidine
IARC 2B (Vol. 115) 2018
EPA Substance Registry System N,N,4-Trimethylaniline (99-97-8)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
Signal word  Danger
Hazard statements  H301+H311-H330-H373-H412
Precautionary statements  P260-P273-P280-P302+P352+P312-P304+P340+P310-P314
target organs Reproductive organs
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  T
Risk Statements  23/24/25-33-52/53
Safety Statements  28-36/37-45-61-28A-51-44-36-22-20/21
RIDADR  1708
WGK Germany  3
RTECS  XU5803000
F  8-10-23
Autoignition Temperature 425 °C
TSCA  TSCA listed
HS Code  2921 43 00
HazardClass  6.1
PackingGroup  II
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Inhalation
Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Aquatic Chronic 3
Carc. 1B
Repr. 2
Skin Sens. 1
STOT RE 2 Oral
Hazardous Substances Data 99-97-8(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 1650 mg/kg
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
3 0

N,N-Dimethyl-p-toluidine price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 41690 4,N,N-Trimethylaniline catalyst grade (for peroxide polymerization), ≥98.5% (GC) 99-97-8 100ml $67.9 2026-04-30 Buy
Sigma-Aldrich 41690 4,N,N-Trimethylaniline catalyst grade (for peroxide polymerization), ≥98.5% (GC) 99-97-8 500ml $155 2026-04-30 Buy
Sigma-Aldrich 8.22040 N,N-Dimethyl-p-toluidine for synthesis 99-97-8 5ML $27.1 2024-03-01 Buy
Sigma-Aldrich 8.22040 N,N-Dimethyl-p-toluidine for synthesis 99-97-8 250ML $68.2 2024-03-01 Buy
Sigma-Aldrich 8.22040 N,N-Dimethyl-p-toluidine for synthesis 99-97-8 1L $139 2024-03-01 Buy
Product number Packaging Price Buy
41690 100ml $67.9 Buy
41690 500ml $155 Buy
8.22040 5ML $27.1 Buy
8.22040 250ML $68.2 Buy
8.22040 1L $139 Buy

N,N-Dimethyl-p-toluidine Chemical Properties, Uses, Production

Chemical Properties

light yellow liquid

Uses

N,N-Dimethyl-4-toluidine is an amine accelerator for the polymerization of e.g. dental methacrylic restorative materials

Uses

N,N-Dimethyl-p-toluidine is used as a polymerization catalyst for polyesters, acrylate and epoxy resins. It is also used as a hardener for dental cements and in adhesives. It serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, pharmaceuticals. It reacts with vinyl ether in the presence of copper(II) chloride gives tetrahydroquinolines. Further, it is used to accelerate polymerization of ethyl methacrylate.

Synthesis Reference(s)

Synthetic Communications, 19, p. 3051, 1989 DOI: 10.1080/00397918908052700
Tetrahedron Letters, 8, p. 1849, 1967

General Description

A clear colorless liquid with an aromatic odor. Density 0.937 g / cm3 (Lancaster) and insoluble in water. Hence floats on water. Toxic by skin absorption and inhalation. Flash point 181°F. May release toxic vapors when burned.

Air & Water Reactions

Tends to darken upon exposure to air. Insoluble in water.

Reactivity Profile

N,N-Dimethyl-p-toluidine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Synthesis

N,N-Dimethyl-p-toluidine was prepared by reacting p-toluidine with methanol and POCl3 in autoclave heated up to 280° C for 3h.

Purification Methods

Reflux for 3hours with 2 molar equivalents of Ac2O, then fractionally distil it under reduced pressure. Alternatively, dry it over BaO, distil and store it over KOH. The picrate has m 128o (from EtOH). Methods described for N,N-dimethylaniline are applicable here. [Beilstein 12 H 902, 12 III 2026, 12 IV 1874.]

Toxics Screening Level

The initial threshold screening level (ITSL) for n,n-dimethyl-p-toluidine (DMPT), is 28 μg/m3 based on an annual averaging time.

N,N-Dimethyl-p-toluidine synthesis

124-38-9
623-08-5
99-97-8
Synthesis of N,N-Dimethyl-p-toluidine from Carbon dioxide and N-Methyl-p-toluidine

N,N-Dimethyl-p-toluidine Preparation Products And Raw materials

Raw materials

Dimethyl sulfate

Preparation Products

Acid Violet 48 N-Methyl-p-toluidine N,4'-dimethylformanilide 2-Bromo-n,n,4-trimethylaniline

N,N-Dimethyl-p-toluidine Suppliers

Global Suppliers ( 479)
Supplier Tel Email Country ProdList Advantage
Changde Changlian Chemical Company Limited 13338951787 1040788229@qq.com China 37 58
Tianjin Zhongxin Chemtech Co., Ltd. 022-66880623 sales@tjzxchem.com China 612 60
Wuhan Qiaofeng Chemical Technology Co., Ltd. 18271818137 2814999308@qq.com China 299 58
Xiangshui Henryda Tech Chemical Co., Ltd. 0512-63863327 13771648447 sales@henryda-chem.com China 53 58
Hubei yongkuo Technology Co., Ltd 027-59223108 15972152991 1248580099@qq.com China 9910 58
Shaoguan Mingtu Chemical Co., Ltd 13411131983 2407385074@qq.com China 2046 58
wenzhou shoucheng 15102776735 793269788@qq.com China 190 58
Zhongshan Dixin Chemical Co., Ltd 0760-1893339-0325 18933390325 274264471@qq.com China 784 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Supplier Advantage
Changde Changlian Chemical Company Limited 58
Tianjin Zhongxin Chemtech Co., Ltd. 60
Wuhan Qiaofeng Chemical Technology Co., Ltd. 58
Xiangshui Henryda Tech Chemical Co., Ltd. 58
Hubei yongkuo Technology Co., Ltd 58
Shaoguan Mingtu Chemical Co., Ltd 58
wenzhou shoucheng 58
Zhongshan Dixin Chemical Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84

Related articles

View Latest Price from N,N-Dimethyl-p-toluidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N-Dimethyl-p-toluidine pictures 2026-09-16 N,N-Dimethyl-p-toluidine
99-97-8
 $15.00-20.00 1000kg 99% 200 mt Anhui Royal Chemical Co., Ltd.
N,N-DIMETHYL-P-TOLUIDINE pictures 2026-09-15 N,N-DIMETHYL-P-TOLUIDINE
99-97-8
 0.99 RongNa Biotechnology Co.,Ltd
N,N-Dimethyl-4-methylaniline pictures 2026-09-15 N,N-Dimethyl-4-methylaniline
99-97-8
 1KG 99% 2000mt/year Jinan Finer Chemical Co., Ltd

N,N-Dimethyl-p-toluidine Spectrum

N,N-DIMETHYL-P-TOLUIDINE(99-97-8)MSN,N-DIMETHYL-P-TOLUIDINE(99-97-8)1HNMRN,N-DIMETHYL-P-TOLUIDINE(99-97-8)13CNMRN,N-DIMETHYL-P-TOLUIDINE(99-97-8)IR1N,N-DIMETHYL-P-TOLUIDINE(99-97-8)IR2N,N-DIMETHYL-P-TOLUIDINE(99-97-8)Raman

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N,N-DIMETHYL-4-METHYLANILINE N,N-DIMETHYL-P-TOLUIDINE Benzeneamine,N,N,4-trimethyl- dimethyl-4-toluidine Dimethyl-p-tolyl-amine Dimetil-p-toluidina n,n,4-trimethyl-benzenamin N,N-Dialkylarylamine(methylgroupinmetaposition) 4,N,N-Trimethylaniline,4-Dimethylaminotoluene, N,N-Dimethyl-p-toluidine 4,N,N-Trimethylanili N,N-DiMethyl-p-toluidine, 99% 500GR N,N-Dimethyl-p-toluidine 4,N,N-Trimethylaniline catalyst grade (for peroxide polymerization), >=98.5% (GC) 4,N,N-Trimethylaniline purum, >=98.0% (GC) N,N,4-Trimethylaniline 4-Dimethylaminotoluene N,N- two Methylp-toluidine 4,N,N-TriMethylaniline 99% 4,N,N-TriMethylaniline, 98%+ N,N,4-trimethyl- N,N-Dimethyl-p-toluidine N,N-Dimethyl-p-toluidine for synthesis 4,N,N-TrimethyL n,n-dimethyl-p-toluidin N,N-Dimethyl-p-tolylamine p-(dimethylamino)toluene p,N,N-trimethylaniline p-Methyl-N,N-dimethylaniline p-Toluidine, N,N-dimethyl- 4,N,N-TRIMETHYLANILINE Tetraphenylphthalicanhydride,98% Benzenamine, N,N,4-trimethyl- DIMETHYLPARA-TOLUIDINE 4-METHYL-N,N-DIMETHYLANILINE PARA-N,N-TRIMETHYLANILINE 4-Dimethylaminotoluene, N,N-Dimethyl-p-toluidine p-Tolyldimethylamine N,N-Dimethyl-p-toluidine,99% DIMETHYLTOLYLAMINE N,N-Dimethyl-p-toluidine > N,N-DIMETHYL-P-TOLUIDINE ISO 9001：2015 REACH N,N-Dimethyl-p-toluidine Purity 99% 4,N,N-Trimethylaniline N,N-Dimethyl-p-toluidine (DMT) N. N-dimethyl-p-toluene 4-DIMETHYLAMINOTOLUENE dimethyltoluidine Dimethyl-p-toluidine N,N,4-TRIMETHYLBENZENAMINE N,N-DIMETHYL-4-TOLUIDINE N,N-Dialkylarylamine N,N-DIMETHYL-PARA-TOLUIDINE N,N,4-Trimethylaniline 99-97-8 CH3C6H4NCH32 Building Blocks Amines C9 to C10 Organic Building Blocks