5-Methoxyindole
- CAS No.
- 1006-94-6
- Chemical Name:
- 5-Methoxyindole
- Synonyms
- 5-METHOXY-1H-INDOLE;Methoxyindole 99% indol-5-yl methyl ether;5-methoxy-indol;Femedol;NSC 521752;AKOS JY2082918;5-METHOXYINDOLE;methoxy-5indole;5-MethoxyindoleF;Methoxy-5 indole
- CBNumber:
- CB4223553
- Molecular Formula:
- C9H9NO
- Molecular Weight:
- 147.17
- MDL Number:
- MFCD00005674
- MOL File:
- 1006-94-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Methoxyindole 99% | M14900 | 1g | $26.8 |
| 5-Methoxyindole 99% | M14900 | 5g | $36.5 |
| 5-Methoxyindole >99.0%(GC) | M0731 | 1g | $42 |
| 5-Methoxyindole >99.0%(GC) | M0731 | 5g | $72 |
| 5-Methoxyindole >99.0%(GC) | M0731 | 25g | $222 |
| More product size | |||
| Melting point | 52-55 °C (lit.) |
|---|---|
| Boiling point | 176-178 °C/17 mmHg (lit.) |
| Density | 1.1135 (rough estimate) |
| refractive index | 1.5310 (estimate) |
| Flash point | 176-178°C/17mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol |
| pka | 16.70±0.30(Predicted) |
| form | Crystalline Powder |
| color | White to light brownish |
| Water Solubility | insoluble |
| Sensitive | Light Sensitive |
| BRN | 116722 |
| InChI | 1S/C9H9NO/c1-11-8-2-3-9-7(6-8)4-5-10-9/h2-6,10H,1H3 |
| InChIKey | DWAQDRSOVMLGRQ-UHFFFAOYSA-N |
| SMILES | COc1ccc2[nH]ccc2c1 |
| CAS DataBase Reference | 1006-94-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | DQM3AS43PQ |
| NIST Chemistry Reference | 1H-Indole, 5-methoxy-(1006-94-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NL9500000 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, KEEP COLD, LIGHT SENSITIVE | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Methoxyindole price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M14900 | 5-Methoxyindole 99% | 1006-94-6 | 1g | $26.8 | 2025-07-31 | Buy |
| Sigma-Aldrich | M14900 | 5-Methoxyindole 99% | 1006-94-6 | 5g | $36.5 | 2025-07-31 | Buy |
| TCI Chemical | M0731 | 5-Methoxyindole >99.0%(GC) | 1006-94-6 | 1g | $42 | 2025-07-31 | Buy |
| TCI Chemical | M0731 | 5-Methoxyindole >99.0%(GC) | 1006-94-6 | 5g | $72 | 2025-07-31 | Buy |
| TCI Chemical | M0731 | 5-Methoxyindole >99.0%(GC) | 1006-94-6 | 25g | $222 | 2025-07-31 | Buy |
5-Methoxyindole Chemical Properties,Uses,Production
Chemical Properties
white to light brownish crystalline powder
Uses
5-Methoxyindole (cas# 1006-94-6) is a compound useful in organic synthesis. It can be used to synthesis 1-(Phenylsulfonyl)-5-methoxy-1H-indole.
Preparation
The synthesis of 5-methoxyindole from 5-methoxy-2-oxindole: Conversion of 5-methoxy-2-oxindole to 5-methoxyindole was accomplishedby the chlorination of 5-methoxy-2-oxindole with triphenylphosphine-carbontetrachloride in acetonitrile followed by the catalytic reduction of a chlorine atom in 66% total yield.
Definition
ChEBI: 5-methoxyindole is a member of indoles.
Reactions
5-methoxyindole was treated with sodium hydroxide and phenylsulfonyl chloride in the presence of a catalytic amount of tetrabutylammonium bromide to afford 1-(phenylsulfonyl)indole and 5-methoxy-1-(phenylsufonyl)indole in excellent yields of 100%.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 1405, 1989 DOI: 10.1002/jhet.5570260533
The Journal of Organic Chemistry, 58, p. 5558, 1993 DOI: 10.1021/jo00072a052
Tetrahedron Letters, 27, p. 837, 1986 DOI: 10.1016/S0040-4039(00)84114-3
Synthesis
The synthesis method of 2-pyridinecarboxaldehyde:the three-component coupling reaction of dicarbonyl compounds, aldehydes, and urea/thiourea catalyzed by indium chloride can be efficiently synthesized.
Purification Methods
Crystallise 5-methoxyindole from cyclohexane pet ether or pet ether/Et2O. [Saito & Kikugawa J Heterocycl Chem 16 1325 1979, Beilstein 21 III/IV 765, 21/3 V 18.]
5-Methoxyindole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8624 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hebei Yiduo Import and Export Co., Ltd. | joycedemei1505@outlook.com | China | 215 | 58 | |
| LAURENT | +8618100176782 | sun@laurentpeg.com | China | 365 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29832 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
View Lastest Price from 5-Methoxyindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-04 | 5-Methoxyindole
1006-94-6
|
US $129.00-645.00 / g | 1g | 0.99 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-02-02 | 5-Methoxyindole
1006-94-6
|
US $0.00-0.00 / KG | 5mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-01-30 | 5-METHOXYINDOLE
1006-94-6
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 5-Methoxyindole
1006-94-6
- US $129.00-645.00 / g
- 0.99
- Shanghai UCHEM Inc.
-
- 5-Methoxyindole
1006-94-6
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-METHOXYINDOLE
1006-94-6
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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