5-Methoxy-2,3-dihydroindoline
- CAS No.
- 21857-45-4
- Chemical Name:
- 5-Methoxy-2,3-dihydroindoline
- Synonyms
- 5-Methoxyindoline;5-METHOXYLINDOLINE; 5-Methoxy-2,3-dihydroindolin;5-METHOXY-2,3-DIHYDROINDOLINE;5-METHOXY-2,3-DIHYDRO-1H-INDOLE;1H-INDOLE, 2,3-DIHYDRO-5-METHOXY-;5-Methoxy-2,3-dihydro-1H-indoline;5-Methoxyindoline 5-Methoxy-2,3-dihydroindoline in stock Factory
- CBNumber:
- CB7267569
- Molecular Formula:
- C9H11NO
- Molecular Weight:
- 149.19
- MDL Number:
- MFCD07368037
- MOL File:
- 21857-45-4.mol
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 283987 | 250mg | $368 |
| 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 283987 | 500mg | $509 |
| 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 283987 | 1g | $831 |
| 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 283987 | 2g | $1165 |
| 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 283987 | 5g | $1416 |
| More product size | |||
| Boiling point | 282.6±29.0 °C(Predicted) |
|---|---|
| Density | 1.076±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | solid |
| pka | 6.07±0.20(Predicted) |
| Appearance | Light yellow to brown Liquid |
| InChI | 1S/C9H11NO/c1-11-8-2-3-9-7(6-8)4-5-10-9/h2-3,6,10H,4-5H2,1H3 |
| InChIKey | YYDYAQAVAHKFJO-UHFFFAOYSA-N |
| SMILES | COc1ccc2NCCc2c1 |
| CAS DataBase Reference | 21857-45-4(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H319-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral |
5-Methoxy-2,3-dihydroindoline price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 283987 | 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 21857-45-4 | 250mg | $368 | 2026-06-03 | Buy |
| Usbiological | 283987 | 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 21857-45-4 | 500mg | $509 | 2026-06-03 | Buy |
| Usbiological | 283987 | 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 21857-45-4 | 1g | $831 | 2026-06-03 | Buy |
| Usbiological | 283987 | 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 21857-45-4 | 2g | $1165 | 2026-06-03 | Buy |
| Usbiological | 283987 | 5-Methoxy-2,3-dihydro-1H-indole hydrochloride Asreported | 21857-45-4 | 5g | $1416 | 2026-06-03 | Buy |
5-Methoxy-2,3-dihydroindoline Chemical Properties,Uses,Production
Synthesis
1006-94-6
21857-45-4
5-Methoxyindole (1.5 g, 10.2 mmol) was dissolved in acetic acid (20 mL) at 25 °C, followed by the addition of sodium cyanoborohydride (0.77 g, 12.2 mmol) in batches. After the reaction lasted for 1 h, the pH of the reaction solution was adjusted to 9-10 with 20% sodium hydroxide solution for neutralization. The reaction mixture was extracted with ethyl acetate (50 mL) and the organic phase was separated and dried over anhydrous sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated by rotary evaporation. Finally, 5-methoxyindoline was purified by column chromatography (eluent: petroleum ether/ethyl acetate, 10:1, v/v) to afford 5-methoxyindoline as a brown solid (1.46 g, 95.9% yield).
References
[1] Organic Letters, 2011, vol. 13, # 19, p. 5124 - 5127
[2] Chemical Communications, 2013, vol. 49, # 63, p. 7052 - 7054
[3] Patent: CN105367474, 2016, A. Location in patent: Paragraph 0194; 0195; 0196; 0197
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 4, p. 479 - 485
[5] Patent: EP1223170, 2002, A1
5-Methoxy-2,3-dihydroindoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1299 | 58 |
| Suzhou Laing Biotechnology Co.,Ltd | +86-13004516015 +86-18149392822 | christina@laingbiotec.com | China | 777 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from 5-Methoxy-2,3-dihydroindoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-17 | 5-Methoxyindoline
21857-45-4
|
$1.10-9.90 | 1KG | 99% min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2020-06-02 | 5-Methoxyindoline 5-Methoxy-2,3-dihydroindoline in stock Factory
21857-45-4
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. | ||
 |
2019-07-06 | 5-Methoxy-2,3-dihydroindoline
21857-45-4
|
$8.00 | 1kg | 99% | 10tons | Career Henan Chemical Co |
-
- 5-Methoxyindoline
21857-45-4
- $1.10-9.90
- 99% min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 5-Methoxyindoline 5-Methoxy-2,3-dihydroindoline in stock Factory
21857-45-4
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- 5-Methoxy-2,3-dihydroindoline
21857-45-4
- $8.00
- 99%
- Career Henan Chemical Co
