1,2-Diamino-4-(trifluoromethoxy)benzene
- CAS No.
- 658-89-9
- Chemical Name:
- 1,2-Diamino-4-(trifluoromethoxy)benzene
- Synonyms
- 4-Trifluoromethoxy-1,2-diaminobenzene;4-(TRIFLUOROMETHOXY)BENZENE-1,2-DIAMINE;4-(Trifluoromethoxy)-1,2-benzenediamine;1,2-Diamino-4-(trifluoromethoxy)benzene;1,2-Benzenediamine, 4-(trifluoromethoxy)-;4-(TRIFLUOROMETHOXY)-1,2-PHENYLENEDIAMINE;4-(Trifluoromethoxy)benzene-1,2-diamine 97%;1,2-Diamino-4-(trifluoromethoxy)benzene, 4-(Trifluoromethoxy)phenylene-1,2-diamine
- CBNumber:
- CB4224853
- Molecular Formula:
- C7H7F3N2O
- Molecular Weight:
- 192.14
- MDL Number:
- MFCD03094278
- MOL File:
- 658-89-9.mol
- MSDS File:
- SDS
| Boiling point | 106-108 °C(Press: 5 Torr) |
|---|---|
| Density | 1.429±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.30±0.10(Predicted) |
| form | Solid |
| color | Dark Brown to Black |
| Stability | Air Sensitive |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H319 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/37/38-43 |
| Safety Statements | 26-36/37/39-36/37 |
| RIDADR | 2810 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 2922290090 |
1,2-Diamino-4-(trifluoromethoxy)benzene price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-D417485-5G | 1,2-Diamino-4-(trifluoromethoxy)benzene | 658-89-9 | 5g | $249 | 2026-06-03 | Buy |
| TRC | TRC-D417485-1G | 1,2-Diamino-4-(trifluoromethoxy)benzene | 658-89-9 | 1g | $91 | 2026-06-03 | Buy |
| Apolloscientific | PC5195 | 4-(Trifluoromethoxy)benzene-1,2-diamine 97% | 658-89-9 | 1g | $25 | 2026-06-04 | Buy |
| Apolloscientific | PC5195 | 4-(Trifluoromethoxy)benzene-1,2-diamine 97% | 658-89-9 | 5g | $101 | 2026-06-04 | Buy |
| Apolloscientific | PC5195 | 4-(Trifluoromethoxy)benzene-1,2-diamine 97% | 658-89-9 | 25g | $500 | 2026-06-04 | Buy |
1,2-Diamino-4-(trifluoromethoxy)benzene Chemical Properties, Uses, Production
Uses
1,2-Diamino-4-(trifluoromethoxy)benzene is a useful synthetic compound.
Synthesis
2267-23-4
658-89-9
General procedure for the synthesis of 4-(trifluoromethoxy)benzene-1,2-diamine from 2-nitro-4-trifluoromethoxyaniline: a solution of 2-nitro-4-trifluoromethoxyaniline (25.0 g, 0.112 mol) in ethanol (200 mL) was slowly added to a solution of concentrated hydrochloric acid (330 mL) of tin chloride dihydrate (82.0 g, 0.363 mol). The reaction mixture was stirred at 70-80°C for 0.5 hours. Upon completion of the reaction, the mixture was cooled to 0-5°C and the pH was adjusted to 11-12 with 40% sodium hydroxide solution.Subsequently, the reaction product was extracted with ether (2 x 200 mL). The organic phases were combined, washed with water and dried over anhydrous sodium sulfate. Finally, the solvent was removed by evaporation under reduced pressure to give 4-(trifluoromethoxy)benzene-1,2-diamine as a brown oil (21.1 g, 98% yield).
References
[1] Patent: WO2006/50148, 2006, A2. Location in patent: Page/Page column 38
[2] Patent: WO2008/75109, 2008, A1. Location in patent: Page/Page column 160
[3] Patent: WO2006/130673, 2006, A1. Location in patent: Page/Page column 115
[4] Patent: WO2006/22954, 2006, A2. Location in patent: Page/Page column 24
[5] Patent: US2014/315963, 2014, A1. Location in patent: Paragraph 0228
1,2-Diamino-4-(trifluoromethoxy)benzene Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-Diamino-4-(trifluoromethoxy)benzene Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Beijing Eternalchem Co,. Ltd. | 010-59484199 18611897322;18611897322; | sales@eternalchem.com | China | 1993 | 60 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 997 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
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