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3-Iodo-tetrahydro-furan

CAS No.
121138-01-0
Chemical Name:
3-Iodo-tetrahydro-furan
Synonyms
3-iodooxolane;3-Iodo-tetrahydro-furan;Furan, tetrahydro-3-iodo-;(RS)-3-iodotetrahydrofuran;Benzoicacid,8-hydroxy-,pentylester
CBNumber:
CB42451930
Molecular Formula:
C4H7IO
Molecular Weight:
198
MDL Number:
MFCD09878873
MOL File:
121138-01-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40

3-Iodo-tetrahydro-furan Properties

Boiling point 187.0±33.0 °C(Predicted)
Density 1.93±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
form liquid
color Dark brown
InChI InChI=1S/C4H7IO/c5-4-1-2-6-3-4/h4H,1-3H2
InChIKey BKIQORJIKOPRCG-UHFFFAOYSA-N
SMILES O1CCC(I)C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2932190090

3-Iodo-tetrahydro-furan price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR52585 3-Iodotetrahydrofuran 98% 121138-01-0 1g $35 2026-06-04 Buy
Apolloscientific OR52585 3-Iodotetrahydrofuran 98% 121138-01-0 5g $122 2026-06-04 Buy
Apolloscientific OR52585 3-Iodotetrahydrofuran 98% 121138-01-0 10g $237 2026-06-04 Buy
Apolloscientific OR52585 3-Iodotetrahydrofuran 98% 121138-01-0 25g $589 2026-06-04 Buy
Apolloscientific OR52585 3-Iodotetrahydrofuran 98% 121138-01-0 100g $2353 2026-06-04 Buy
Product number Packaging Price Buy
OR52585 1g $35 Buy
OR52585 5g $122 Buy
OR52585 10g $237 Buy
OR52585 25g $589 Buy
OR52585 100g $2353 Buy

3-Iodo-tetrahydro-furan Chemical Properties, Uses, Production

Physical Form

liquid

Uses

3-Iodotetrahydrofuran is used to study transition-metal-free Heck-type reaction between alkenes and alkyl iodides enabled by light in water.

Synthesis

3-Hydroxytetrahydrofuran

453-20-3

3-IODO-TETRAHYDRO-FURAN

121138-01-0

3-Hydroxytetrahydrofuran (8.8 g, 0.1 mol) was used as starting material and dissolved in dichloromethane (200 mL). Triphenylphosphine (52.4 g, 0.2 mol), imidazole (13.6 g, 0.2 mol) and iodine (50.7 g, 0.2 mol) were added sequentially to this solution. The reaction mixture was heated to reflux overnight under nitrogen protection. Upon completion of the reaction, 0.2 M sodium thiosulfate solution (30 mL) was added to quench the reaction. The organic layer was separated and the aqueous phase was extracted with dichloromethane. The organic phases were combined, dried over anhydrous magnesium sulfate, filtered and concentrated to give a wet yellow solid. The solid was dissolved in pentane (100 mL) and stirred for 2 h. The insoluble material was removed by filtration and the filtrate was concentrated to give the final 3-iodotetrahydrofuran (18.6 g, 94% yield).

References

[1] Patent: CN103965174, 2016, B. Location in patent: Paragraph 0171; 0173-0175
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 22, p. 6170 - 6174
[3] Angewandte Chemie - International Edition, 2013, vol. 52, # 3, p. 933 - 937
[4] Angew. Chem., 2012, vol. 125, # 3, p. 967 - 971,5

3-Iodo-tetrahydro-furan Preparation Products And Raw materials

Global Suppliers ( 102)
Supplier Tel Email Country ProdList Advantage
Shanghai Sunmonth Technology Co., LTD 15216675652 xuanyuelj@163.com China 3000 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Shanghai Sheepchem Co., Ltd. +86 (21) 6715-7650 sheepchem@163.com China 993 60
Shanghai ChriChem Co., Ltd. 021-54880687 China 510 55

View Latest Price from 3-Iodo-tetrahydro-furan manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Iodotetrahydrofuran pictures 2026-09-18 3-Iodotetrahydrofuran
121138-01-0
1KG 95%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
3-IODO-TETRAHYDRO-FURAN pictures 2024-02-26 3-IODO-TETRAHYDRO-FURAN
121138-01-0
1kg 95% BTC Nantong Pharmaceuticals Technology Co.,Ltd
3-IODO-TETRAHYDRO-FURAN pictures 2019-07-06 3-IODO-TETRAHYDRO-FURAN
121138-01-0
$1.00 1KG 98% 500kg Career Henan Chemical Co

3-Iodo-tetrahydro-furan Spectrum

3-iodooxolane Furan, tetrahydro-3-iodo- (RS)-3-iodotetrahydrofuran Benzoicacid,8-hydroxy-,pentylester 3-Iodo-tetrahydro-furan 121138-01-0