Artemether
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Artemether 속성
- 녹는점
- 86-88°C
- 끓는 점
- 359.79°C (rough estimate)
- 알파
- D19.5 +171° (c = 2.59 in CHCl3)
- 밀도
- 1.0733 (rough estimate)
- 굴절률
- 1.6200 (estimate)
- 저장 조건
- room temp
- 용해도
- DMSO: ≥20mg/mL
- 물리적 상태
- 가루
- 색상
- 황백색부터 연한 갈색까지
- 광학 활성
- [α]/D +155 to +175°, c = 0.5 in methanol
- Merck
- 14,815
- InChI
- InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1
- InChIKey
- SXYIRMFQILZOAM-HVNFFKDJSA-N
- SMILES
- O1[C@]23[C@@]4([H])O[C@@](C)(CC[C@@]2([H])[C@H](C)CC[C@@]3([H])[C@@H](C)[C@@H](OC)O4)O1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22 | ||
| 안전지침서 | 24/25 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | KD4165000 | ||
| HS 번호 | 29329930 | ||
| 스토리지 클래스 | 5.2 - Organic peroxides and self-reacting hazardous materials | ||
| Hazard Classifications | Acute Tox. 4 Oral Org. Perox. D |
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| 유해 물질 데이터 | 71963-77-4(Hazardous Substances Data) | ||
| 독성 | LD50 i.m. in mice: 263 mg/kg (China Cooperative Research Group on Qinghaosu) |
Artemether MSDS
[3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
Artemether C화학적 특성, 용도, 생산
개요
Artemether is an antiparasitic compound and a derivative of artemisinin . It induces mortality in adult wild-type and pfatp6-mutant P. falciparum but the efficacy is decreased in the mutants (IC50s = 8.2 and 13.5 nM, respectively). Artemether reduces parasitemia in P. falciparum-infected monkeys and P. berghei-infected mice with 50% curative dose (CD50) values of 7.1 and 55 mg/kg, respectively. It also reduces the worm burden of S. mansoni trematodes in mice when used at doses ranging from 200 to 500 mg/kg. Formulations containing artemether have been used in the treatment of malaria.화학적 성질
White Solid용도
Artemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when정의
ChEBI: An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falcip rum malaria.일반 설명
Artemisinin (ART) is a natural compound present in Artemisia annua, a traditional Chinese plant.Safety Profile
Poison by intramuscular route.Experimental reproductive effects. When heated todecomposition it emits acrid smoke and irritating fumes.Artemether 준비 용품 및 원자재
원자재
준비 용품
Artemether 공급 업체
글로벌( 684)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 |
tongyibiochem@163.com | China | 2995 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 |
sale03@alfachem.cn | China | 9796 | 58 |
| Vinsce Bio pharm (Suzhou) Co Ltd | +undefined13962217456 |
info@vinsce.com | China | 38 | 58 |
| HIGH HOPE PBC HK CO., LIMITED | +86-852-52715977 +8618694976128 |
sales@pharma-bridge.com | China | 34 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 |
sales1@chuanghaibio.com | China | 5225 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 |
deasea125996@gmail.com | China | 2472 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 973 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
sarah@tnjone.com | China | 1143 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019; +8615350851019 |
admin@86-ss.com | China | 999 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 |
Jerry@xhobio.com | China | 906 | 58 |