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2-Fluoro-4-nitrophenylacetic acid

CAS No.
315228-19-4
Chemical Name:
2-Fluoro-4-nitrophenylacetic acid
Synonyms
2-Fluoro-4-nitrophenylacetic acid;2-fluoro-4-nitroBenzeneacetic acid;2-(2-Fluoro-4-nitrophenyl)acetic acid;Benzeneacetic acid, 2-fluoro-4-nitro-
CBNumber:
CB42482916
Molecular Formula:
C8H6FNO4
Molecular Weight:
199.14
MDL Number:
MFCD11041422
MOL File:
315228-19-4.mol
MSDS File:
SDS
Last updated:2026-05-28 01:52:56

2-Fluoro-4-nitrophenylacetic acid Properties

Boiling point 376.3±27.0 °C(Predicted)
Density 1.498±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.58±0.10(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H335-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362
HazardClass  IRRITANT

2-Fluoro-4-nitrophenylacetic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech CX1226 (2-FLUORO-4-NITRO-PHENYL)-ACETIC ACID 98% 315228-19-4 1G $21 2026-04-30 Buy
Biosynth QMA22819 2-Fluoro-4-nitrophenylacetic acid 315228-19-4 10g $354 2026-06-04 Buy
Matrix Scientific 048490 2-Fluoro-4-nitrophenylacetic acid 315228-19-4 25.00g $61 2026-05-18 Buy
Matrix Scientific 048490 2-Fluoro-4-nitrophenylacetic acid 315228-19-4 100.00g $244 2026-05-18 Buy
Matrix Scientific 048490 2-Fluoro-4-nitrophenylacetic acid 315228-19-4 500.00g $1211 2026-05-18 Buy
Product number Packaging Price Buy
CX1226 1G $21 Buy
QMA22819 10g $354 Buy
048490 25.00g $61 Buy
048490 100.00g $244 Buy
048490 500.00g $1211 Buy

2-Fluoro-4-nitrophenylacetic acid Chemical Properties, Uses, Production

Uses

(2-Fluoro-4-nitrophenyl)acetic acid

Synthesis

Diethyl 2-(2-fluoro-4-nitrophenyl)Malonate

318471-58-8

2-Fluoro-4-nitrophenylacetic acid

315228-19-4

Step 2: Diethyl 2-(2-fluoro-4-nitrophenyl)malonate (12) (12.0 g) was dissolved in a mixed solvent of acetic acid (80 mL) and water (30 mL) and concentrated sulfuric acid (20 mL) was added slowly. The reaction mixture was heated to 100 °C and the reaction was stirred overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Water (100 mL) was added to the residue and the aqueous phase was extracted with ethyl acetate (200 mL x 2). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-(2-fluoro-4-nitrophenyl)acetic acid (7.0 g), the product was a light yellow oil.

References

[1] Patent: US2003/225107, 2003, A1. Location in patent: Page 45
[2] Patent: WO2013/29338, 2013, A1. Location in patent: Page/Page column 126; 127

2-Fluoro-4-nitrophenylacetic acid Preparation Products And Raw materials

Global Suppliers ( 64)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Beijing Eternalchem Co,. Ltd. 010-59484199 18611897322;18611897322; sales@eternalchem.com China 1993 60
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

View Latest Price from 2-Fluoro-4-nitrophenylacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluoro-4-nitrophenylacetic acid pictures 2020-01-09 2-Fluoro-4-nitrophenylacetic acid
315228-19-4
$1.00 1KG 95-99% 1ton Career Henan Chemical Co

2-Fluoro-4-nitrophenylacetic acid Spectrum

2-Fluoro-4-nitrophenylacetic acid Benzeneacetic acid, 2-fluoro-4-nitro- 2-(2-Fluoro-4-nitrophenyl)acetic acid 2-fluoro-4-nitroBenzeneacetic acid 315228-19-4