2-Fluoro-5-nitrophenylacetic acid
- CAS No.
- 195609-18-8
- Chemical Name:
- 2-Fluoro-5-nitrophenylacetic acid
- Synonyms
- 2-FLUORO-5-NITROPHENYLACETIC;2-fluoro-5-nitrophenyl acetate;2-Fluoro-5-nitrophenylacetic acid;2-(2-fluoro-5-nitrophenyl)aceticaci;Benzeneacetic acid, 2-fluoro-5-nitro-;2-(2-Fluoro-5-nitrophenyl)acetic acid;3-(Carboxymethyl)-4-fluoronitrobenzene;2-FLUORO-5-NITROPHENYLACETIC ACID ISO 9001：2015 REACH
- CBNumber:
- CB9730131
- Molecular Formula:
- C8H6FNO4
- Molecular Weight:
- 199.14
- MDL Number:
- MFCD04091773
- MOL File:
- 195609-18-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HazardClass | IRRITANT |
| HS Code | 2916399090 |
2-Fluoro-5-nitrophenylacetic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC7840 | 2-Fluoro-5-nitrophenylacetic acid ≥95% | 195609-18-8 | 10g | $36 | 2026-06-04 | Buy |
| Apolloscientific | PC7840 | 2-Fluoro-5-nitrophenylacetic acid ≥95% | 195609-18-8 | 25g | $63 | 2026-06-04 | Buy |
| Apolloscientific | PC7840 | 2-Fluoro-5-nitrophenylacetic acid ≥95% | 195609-18-8 | 100g | $183 | 2026-06-04 | Buy |
| Matrix Scientific | 024824 | 2-Fluoro-5-nitrophenylacetic acid | 195609-18-8 | 25.00g | $55 | 2026-05-18 | Buy |
| Matrix Scientific | 024824 | 2-Fluoro-5-nitrophenylacetic acid | 195609-18-8 | 100.00g | $195 | 2026-05-18 | Buy |
2-Fluoro-5-nitrophenylacetic acid Chemical Properties, Uses, Production
Chemical Properties
Light yellow crystalline
Uses
2-Fluoro-5-nitrophenylacetic acid can be used to prepare thickened heterocyclic compounds as protein kinase inhibitors.
Synthesis
451-82-1
195609-18-8
General procedure for the synthesis of 2-fluoro-5-nitrophenylacetic acid from o-fluorophenylacetic acid: o-fluorobenzoic acid (30.0 g, 0.19 mol) was dissolved in a mixed solution of concentrated sulfuric acid (50 mL) and water (10 mL). A mixed solution of fuming nitric acid (10 mL) and water (10 mL) was added slowly and dropwise at 0 °C. The reaction mixture was kept stirred at 0 °C for 30 min. Upon completion of the reaction, the resulting precipitate was collected by filtration and washed with cold water. Finally, the product was dried under vacuum to afford 2-(2-fluoro-5-nitrophenyl)acetic acid as a white solid (35.2 g, 91% yield).
References
[1] Patent: WO2010/91310, 2010, A1. Location in patent: Page/Page column 99
[2] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 15, p. 2229 - 2235
[3] Tetrahedron, 2000, vol. 56, # 50, p. 9809 - 9818
[4] Patent: US2006/30609, 2006, A1. Location in patent: Page/Page column 15
2-Fluoro-5-nitrophenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
View Latest Price from 2-Fluoro-5-nitrophenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-(2-fluoro-5-nitrophenyl)acetic acid
195609-18-8
|
20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | ||
 |
2026-09-02 | 2-(cyclopentyloxy)benzoic acid
195609-18-8
|
20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | ||
 |
2026-09-02 | 2-FLUORO-5-NITROPHENYLACETIC ACID
195609-18-8
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd |
-
- 2-(2-fluoro-5-nitrophenyl)acetic acid
195609-18-8
- $0.00
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- 2-(cyclopentyloxy)benzoic acid
195609-18-8
- $0.00
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- 2-FLUORO-5-NITROPHENYLACETIC ACID
195609-18-8
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
