Phosphonium, (2-methoxyethyl)triphenyl-, bromide
- CAS No.
- 55894-16-1
- Chemical Name:
- Phosphonium, (2-methoxyethyl)triphenyl-, bromide
- Synonyms
- Nsc280056;Triprolidine Impurity 3;(2-Methoxyethyl)triphenyl;(2-Methoxyethyl)(triphenyl)phosphoniuM;METHOXYETHYLTRIPHENYLPHOSPHONIUM BROMIDE;(2-Methoxyethyl)triphenylphosphoniuM broMide;Phosphonium, (2-methoxyethyl)triphenyl-, bromide;(2-methoxyethyl)triphenyl-Phosphonium bromide (1:1);Phosphonium, (2-methoxyethyl)triphenyl-, bromide (1:1);(2-
METHOXY- ETHYL) - TRIPHENYL- PHOSPHONIUM, BROMIDE
- CBNumber:
- CB42495455
- Molecular Formula:
- C21H22OP.Br
- Molecular Weight:
- 401.28
- MDL Number:
- MFCD00195808
- MOL File:
- 55894-16-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
Phosphonium, (2-methoxyethyl)triphenyl-, bromide price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S80846 | (2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE AldrichCPR | 55894-16-1 | 1 unit | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | S80846 | (2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE Aldrich | 55894-16-1 | 250mg | $110 | 2024-03-01 | Buy |
| ChemScene | CS-0031359 | Phosphonium, (2-methoxyethyl)triphenyl-, bromide 1:1 ≥97% | 55894-16-1 | 5g | $19 | 2026-06-04 | Buy |
| ChemScene | CS-0031359 | Phosphonium, (2-methoxyethyl)triphenyl-, bromide 1:1 ≥97% | 55894-16-1 | 10g | $36 | 2026-06-04 | Buy |
| ChemScene | CS-0031359 | Phosphonium, (2-methoxyethyl)triphenyl-, bromide 1:1 ≥97% | 55894-16-1 | 25g | $68 | 2026-06-04 | Buy |
Phosphonium, (2-methoxyethyl)triphenyl-, bromide Chemical Properties, Uses, Production
Uses
(2-Methoxyethyl)triphenylphosphonium Bromide is an intermediate for the synthesis of (Z)-Triprolidine Oxalate Salt (T814007), which is an antihistaminic agent with anticholinergic properties. Triprolidine is used to treat and prevent symptoms associated with allergies. Triprolidine is also used in combination with cold medicine to provide relief for flu-like symptoms.
Synthesis
603-35-0
6482-24-2
55894-16-1
a) Triphenylphosphine (300 g, 1.14 mol) and 2-bromoethyl methyl ether (200 g, 1.43 mol) were refluxed in toluene (1 L) for 24 hours. Upon completion of the reaction, the reaction mixture was cooled to 30 °C and filtered to afford (2-methoxyethyl)triphenylphosphonium bromide (450 g, 78%). Subsequently, the product (450 g) was reacted with pyrrolidine (96 g, 1.37 mol) in methanol (500 mL) at 60°C for 2 hours. At the end of the reaction, methanol was removed by distillation and the resulting solid was suspended in toluene (appropriate amount), cooled to 30°C and filtered to give 2-(1-pyrrolidinyl)ethyltriphenylphosphonium bromide (450 g, 91%).NMR (D2O) δ: 1.67 (m, 4H), 2.46 (m, 4H), 2.78 (m, 2H), 3.41 (m, 2H), 7.68 ( m, 15H).
References
[1] Tetrahedron Letters, 2008, vol. 49, # 5, p. 824 - 826
[2] Patent: WO2007/141803, 2007, A2. Location in patent: Page/Page column 5-6
Phosphonium, (2-methoxyethyl)triphenyl-, bromide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2227 | 55 |
| BeiJing Greenchem Technology Co.,Ltd. | 131-21959385 18804271668 | chemrocking@bjgreenchem.com | China | 272 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Watson Biotechnology Co.,Ltd | 027-59207879 1972026995 18140587686 | sales@3600chem.com | China | 4189 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9787 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from Phosphonium, (2-methoxyethyl)triphenyl-, bromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-15 | (2-Methoxyethyl)(triphenyl)phosphonium
55894-16-1
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2025-04-04 | Phosphonium, (2-methoxyethyl)triphenyl-, bromide
55894-16-1
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2020-11-16 | Phosphonium, (2-methoxyethyl)triphenyl-, bromide
55894-16-1
|
$20.00 | 1KG | 99% | 10000KG | Longyan Tianhua Biological Technology Co., Ltd |
-
- (2-Methoxyethyl)(triphenyl)phosphonium
55894-16-1
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Phosphonium, (2-methoxyethyl)triphenyl-, bromide
55894-16-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Phosphonium, (2-methoxyethyl)triphenyl-, bromide
55894-16-1
- $20.00
- 99%
- Longyan Tianhua Biological Technology Co., Ltd
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