H2N-PEG6-tBu
- CAS No.
- 1286281-32-0
- Chemical Name:
- H2N-PEG6-tBu
- Synonyms
- tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate;H2N-PEG6-CH2CH2COOtBu;NH2-PEG6-CH2CH2COOtBu;NH2-PEG6-Boc;H2N-PEG6-tBu;NH2-PEG6-TBA;H2N-PEG5-COOtBu;NH2-PEG6-COOtBu;Amino-PEG6-COOtBu;NH2-PEG7-CH2COOtBu
- CBNumber:
- CB42546870
- Molecular Formula:
- C19H39NO8
- Molecular Weight:
- 409.51
- MDL Number:
- MFCD13184944
- MOL File:
- 1286281-32-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Amino-PEG6-t-butyl ester | 902659 | 250MG | $204 |
| Amino-PEG6-t-butyl ester | 902659 | 1G | $746 |
| H2N-PEG6-tBu | FP73073 | 250mg | $150 |
| H2N-PEG6-tBu | FP73073 | 100mg | $150 |
| H2N-PEG6-tBu | FP73073 | 50mg | $150 |
| More product size | |||
| Boiling point | 475.9±40.0 °C(Predicted) |
|---|---|
| Density | 1.056±0.06 g/cm3(Predicted) |
| refractive index | n/D 1.4562 |
| storage temp. | -20°C |
| form | Oil |
| pka | 8.74±0.10(Predicted) |
| color | Colorless to light yellow |
| InChI | InChI=1S/C19H39NO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17,20H2,1-3H3 |
| InChIKey | QGSFECNPSLZGGT-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCN |
| UNSPSC Code | 51171641 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| HS Code | 2942000090 |
| Storage Class | 10 - Combustible liquids |
H2N-PEG6-tBu price More Price(130)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 902659 | Amino-PEG6-t-butyl ester | 1286281-32-0 | 250MG | $204 | 2026-04-30 | Buy |
| Sigma-Aldrich | 902659 | Amino-PEG6-t-butyl ester | 1286281-32-0 | 1G | $746 | 2026-04-30 | Buy |
| Biosynth | FP73073 | H2N-PEG6-tBu | 1286281-32-0 | 250mg | $150 | 2026-06-04 | Buy |
| Biosynth | FP73073 | H2N-PEG6-tBu | 1286281-32-0 | 100mg | $150 | 2026-06-04 | Buy |
| Biosynth | FP73073 | H2N-PEG6-tBu | 1286281-32-0 | 50mg | $150 | 2026-06-04 | Buy |
H2N-PEG6-tBu Chemical Properties,Uses,Production
Description
Amino-PEG6-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC molecules) for targeted protein degradation.
reaction suitability
reagent type: cross-linking reagent
IC 50
PEGs; Alkyl/ether; Non-cleavable Linker
H2N-PEG6-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changsha Morning Shine Co., Ltd. | +8619973113652 | chenkaijie@csmspharm.com | China | 249 | 58 |
| LAURENT | +8618100176782 | sun@laurentpeg.com | China | 365 | 58 |
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
View Lastest Price from H2N-PEG6-tBu manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-05 | tert-butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate
1286281-32-0
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2026-01-28 | NH2-PEG6-CH2CH2COOtBu
1286281-32-0
|
1g | 98% | 200kg | LAURENT | ||
 |
2025-06-07 | Amino-PEG6-COOtBu
1286281-32-0
|
250mg | >98.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- tert-butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate
1286281-32-0
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- NH2-PEG6-CH2CH2COOtBu
1286281-32-0
- 98%
- LAURENT
-
- Amino-PEG6-COOtBu
1286281-32-0
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
