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N-succiniMidyl 4-(2-pyridyldithio)pentanoate

N-succiniMidyl 4-(2-pyridyldithio)pentanoate Structure
N-succiniMidyl 4-(2-pyridyldithio)pentanoate structure
CAS No.
341498-08-6
Chemical Name:
N-succiniMidyl 4-(2-pyridyldithio)pentanoate
Synonyms
N-succiniMidyl 4-(2-pyridyldithio)pentanoate;N-succinimidyl 4-(2-pyridyldithio)-pentanoate / SPP;2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfanyl)pentanoate;2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfaneyl)pentanoate;4-(Pyridin-2-yldisulfanyl)pentanoic acid N-Hydroxy succinimide ester;Pentanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB42730828
Molecular Formula:
C14H16N2O4S2
Molecular Weight:
340.41784
MDL Number:
MFCD20230233
MOL File:
341498-08-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:24:08
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N-succiniMidyl 4-(2-pyridyldithio)pentanoate Properties

Melting point 48-49 °C
Boiling point 483.5±55.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Storage temp. -20°C
pka 1.83±0.19(Predicted)
form Solid
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

N-succiniMidyl 4-(2-pyridyldithio)pentanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0102531 SPP ≥95% 341498-08-6 100mg $90 2026-06-04 Buy
ChemScene CS-0102531 SPP ≥95% 341498-08-6 250mg $120 2026-06-04 Buy
ChemScene CS-0102531 SPP ≥95% 341498-08-6 1g $335 2026-06-04 Buy
ChemScene CS-0102531 SPP ≥95% 341498-08-6 5g $1334 2026-06-04 Buy
BroadPharm bp-40161 N-Succinimidyl 4-(2-pyridyldithio)pentanoate 341498-08-6 100MG $110 2026-05-24 Buy
Product number Packaging Price Buy
CS-0102531 100mg $90 Buy
CS-0102531 250mg $120 Buy
CS-0102531 1g $335 Buy
CS-0102531 5g $1334 Buy
bp-40161 100MG $110 Buy

N-succiniMidyl 4-(2-pyridyldithio)pentanoate Chemical Properties, Uses, Production

Uses

SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate[1].

IC 50

Cleavable Linker; Disulfide Cleavable Linker

References

[1] Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73. DOI:10.1021/mp5007757

N-succiniMidyl 4-(2-pyridyldithio)pentanoate Preparation Products And Raw materials

Raw materials

Preparation Products

N-succiniMidyl 4-(2-pyridyldithio)pentanoate Suppliers

Global Suppliers ( 51)
Supplier Tel Email Country ProdList Advantage
Jinan Trio PharmaTech Co., Ltd. 0531-88811783 sales@trio-pharmatech.com China 1856 62
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Wellman Pharmaceutical Group Limited 15807197853 18971451745 15807197853@163.com China 3976 58
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
Supplier Advantage
Jinan Trio PharmaTech Co., Ltd. 62
Bide Pharmatech Ltd. 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Wellman Pharmaceutical Group Limited 58
Aikon International Limited 58
Xi'an Confluore Biological Technology Co., Ltd. 58
SuZhou Medinoah Co.,LTD. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58

View Latest Price from N-succiniMidyl 4-(2-pyridyldithio)pentanoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SPP pictures 2026-05-11 SPP
341498-08-6
 $34.00-75.00 98.00% 10g TargetMol Chemicals Inc.
  • SPP pictures
  • SPP
    341498-08-6
  • $34.00-75.00
  • 98.00%
  • TargetMol Chemicals Inc.

N-succiniMidyl 4-(2-pyridyldithio)pentanoate Spectrum

N-succiniMidyl 4-(2-pyridyldithio)pentanoate(341498-08-6)1HNMR

341498-08-6 (N-succiniMidyl 4-(2-pyridyldithio)pentanoate) Related Search:

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol N,N'-Ethylenebis(stearamide) Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate
SPDP-Gly-Pro-NHS ester

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4-(Pyridin-2-yldisulfanyl)pentanoic acid N-Hydroxy succinimide ester N-succinimidyl 4-(2-pyridyldithio)-pentanoate / SPP N-succiniMidyl 4-(2-pyridyldithio)pentanoate 2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfaneyl)pentanoate 2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfanyl)pentanoate Pentanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester 341498-08-6