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N-succiniMidyl 4-(2-pyridyldithio)pentanoate

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N-succiniMidyl 4-(2-pyridyldithio)pentanoate manufacturers

  • SPP
  • SPP pictures
  • $34.00
  • 2026-05-11
  • CAS:341498-08-6
  • Purity: 98.00%
  • Supply Ability: 10g
N-succiniMidyl 4-(2-pyridyldithio)pentanoate Basic information
Product Name:N-succiniMidyl 4-(2-pyridyldithio)pentanoate
Synonyms:4-(Pyridin-2-yldisulfanyl)pentanoic acid N-Hydroxy succinimide ester;N-succinimidyl 4-(2-pyridyldithio)-pentanoate / SPP;N-succiniMidyl 4-(2-pyridyldithio)pentanoate;2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfaneyl)pentanoate;2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfanyl)pentanoate;Pentanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
CAS:341498-08-6
MF:C14H16N2O4S2
MW:340.41784
EINECS:636-474-6
Product Categories:
Mol File:341498-08-6.mol
N-succiniMidyl 4-(2-pyridyldithio)pentanoate Structure
N-succiniMidyl 4-(2-pyridyldithio)pentanoate Chemical Properties
Melting point 48-49 °C
Boiling point 483.5±55.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
storage temp. Storage temp. -20°C
pka1.83±0.19(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
N-succiniMidyl 4-(2-pyridyldithio)pentanoate Usage And Synthesis
UsesSPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate[1].
IC 50Cleavable Linker; Disulfide Cleavable Linker
References[1] Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73. DOI:10.1021/mp5007757
N-succiniMidyl 4-(2-pyridyldithio)pentanoate Preparation Products And Raw materials
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