ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN
- CAS No.
- 11002-13-4
- Chemical Name:
- ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN
- Synonyms
- DRVYIHPFHLVIHN;ANGIOTENSINOGEN;RENIN SUBSTRATE;hypertensinogen;ANGIOTENSINOGEN 1-14;RENIN SUBSTRATE, HUMAN;PREANGIOTENSINOGEN 1-14;HUMAN PREANGIOTENSINOGEN 1-14;ANGIOTENSINOGEN FRAGMENT 1-14;ANGIOTENSINOGEN (1-14) (HUMAN)
- CBNumber:
- CB4277703
- Molecular Formula:
- C83H122N24O19
- Molecular Weight:
- 1760.01
- MDL Number:
- MFCD00133096
- MOL File:
- 11002-13-4.mol
| Product description | Number | Pack Size | Price |
| Angiotensinogen from human plasma ≥80% (SDS-PAGE), lyophilized powder | A2562 | 0.1mg | $574 |
| Angiotensinogen (1-14), human | VAC-00343 | 5mg | $363 |
| Angiotensinogen (1-14), human | VAC-00343 | 10mg | $605 |
| Angiotensinogen (1-14), human | VAC-00343 | 25mg | $1210 |
| Angiotensinogen, human plasma | LAA00213 | 1mg | $5354.25 |
| storage temp. | −20°C |
|---|---|
| solubility | water: soluble |
| form | lyophilized powder |
| color | white |
| Water Solubility | water: soluble |
| FDA UNII | MU4K37ZE5W |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A2562 | Angiotensinogen from human plasma ≥80% (SDS-PAGE), lyophilized powder | 11002-13-4 | 0.1mg | $574 | 2026-04-30 | Buy |
| Biosynth | VAC-00343 | Angiotensinogen (1-14), human | 5mg | $363 | 2026-06-05 | Buy | |
| Biosynth | VAC-00343 | Angiotensinogen (1-14), human | 10mg | $605 | 2026-06-05 | Buy | |
| Biosynth | VAC-00343 | Angiotensinogen (1-14), human | 25mg | $1210 | 2026-06-05 | Buy | |
| Biosynth | LAA00213 | Angiotensinogen, human plasma | 11002-13-4 | 1mg | $5354.25 | 2026-06-04 | Buy |
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN Chemical Properties,Uses,Production
Uses
Angiotensinogen has been used for the detection and analysis of the complexes formed between angiotensinogen and proform of eosinophil major basic protein (ProMBP) in both serum and amniotic fluid during pregnancy through ELISA.
Biological Functions
Human plasma contains a glycoprotein called angiotensinogen, which serves as the only known substrate for renin. Angiotensinogen must undergo proteolysis before active portions of the protein are sufficiently unmasked to exert biological effects. Angiotensinogen is synthesized in many organs, including the liver, brain, kidney, and fat. Its gene transcription and plasma concentrations increase following treatment with adrenocorticotropic hormone (ACTH), glucocorticoids, thyroid hormone, and estrogens, as well as during pregnancy and inflammation and after nephrectomy. Angiotensinogen also has been found in large quantities in cerebrospinal and amniotic fluid. Mutations in the angiotensinogen gene have been reported to be linked to human hypertension.
Biological Activity
Angiotensinogen acts as a precursor molecule in the renin-angiotensin-aldosterone system (RAAS) pathway. It is a part of the renin-angiotensin system th at regulates blood pressure and fluid balance. Moreover, overactivation of the RAAS system has been associated with the development of several types of cancer, cardiovascular and renal diseases. Furthermore, in certain cancers angiotensin II has been shown to promote cancer metastasis.
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN Preparation Products And Raw materials
Raw materials
Preparation Products
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52906 | 58 | |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7858 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7431 | 58 |
| Merck KGaA | -- | ordercn@merckgroup.com | China | 6376 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6032 | 58 |
| Cohesion Biosciences | -- | sales@cohesionbio.com | China | 6282 | 58 |
