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ASP-ARG-VAL-TYR-ILE-HIS-PRO

CAS No.
51833-78-4
Chemical Name:
ASP-ARG-VAL-TYR-ILE-HIS-PRO
Synonyms
Merotocin;A779;Talfirastide;ANGIOTENSIN (1-7);DRVYIHP;Ang-(1-7);DRVYIH{D-Ala};H2N-DRVYIHP-OH;angiotension 1-7;angiotensinii(1-7
CBNumber:
CB6196808
Molecular Formula:
C41H62N12O11
Molecular Weight:
899.01
MDL Number:
MFCD00153513
MOL File:
51833-78-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

ASP-ARG-VAL-TYR-ILE-HIS-PRO Properties

Melting point >202°C (dec.)
Density 1.47±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
form powder
pka 3.29±0.20(Predicted)
color White to Off-White
Water Solubility Soluble to 1 mg/ml in water
InChIKey PVHLMTREZMEJCG-UHFFFAOYSA-N
SMILES CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)N3CCCC3C(O)=O
EWG's Food Scores 1
FDA UNII IJ3FUK8MOF
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P403+P233-P405-P501
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
Storage Class 11 - Combustible Solids

ASP-ARG-VAL-TYR-ILE-HIS-PRO price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A9202 Angiotensin Fragment 1-7 acetate salt hydrate ≥90% (HPLC), powder 51833-78-4 1mg $87.1 2026-04-30 Buy
Sigma-Aldrich A9202 Angiotensin Fragment 1-7 acetate salt hydrate ≥90% (HPLC), powder 51833-78-4 5mg $311 2026-04-30 Buy
Usbiological 545083 Angiotensin 1-7 PurifiedbyProteinAandpeptideaffinitychromatography. 200ul $591 2026-06-03 Buy
Usbiological 545082 Angiotensin 1-7 PurifiedbyProteinAandpeptideaffinitychromatography. 200ul $591 2026-06-03 Buy
Usbiological 545081 Angiotensin 1-7 PurifiedbyProteinA/Gaffinitychromatography. 200ul $602 2026-06-03 Buy
Product number Packaging Price Buy
A9202 1mg $87.1 Buy
A9202 5mg $311 Buy
545083 200ul $591 Buy
545082 200ul $591 Buy
545081 200ul $602 Buy

ASP-ARG-VAL-TYR-ILE-HIS-PRO Chemical Properties,Uses,Production

Uses

Angiotensin (1-7) can be used in biological study and engineering or chemical process of mechanisms of peptide oxidation by hydroxyl radicals.

Definition

ChEBI: Ile(5)-angiotensin II (1-7) is an angiotensin compound consisting of the linear heptapeptide sequence L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro. It has a role as a vasodilator agent. It is a tautomer of an Ile(5)-angiotensin II (1-7) dizwitterion.

Biological Activity

ang-(1-7) (h - asp - arg - val - tyr - ile - his - pro - oh) is an endogenous peptide fragment that can be produced from ang i or ang ii via endo- or carboxy-peptidases respectively[1].as described for ang ii, ang-(1-7) also has a broad range of effects in different organs and tissues and goes beyond its initially described cardiovascular and renal actions. those effects are mediated by mas and can counter-regulate most of the deleterious effects of ang ii. the interaction ang-(1-7)/mas regulates different signaling pathways, such as pi3k (phosphoinositide 3-kinase)/akt and erk (extracellular signal-regulated kinase) pathways and involves downstream effectors such as no, foxo1 (forkhead box o1) and cox-2 (cyclo-oxygenase-2). through these mechanisms, ang-(1-7) is able to improve pathological conditions including fibrosis and inflammation in organs such as lungs, liver and kidney. [2]in addition, this heptapeptide has positive effects on metabolism, increasing the glucose uptake and lipolysis while decreasing insulin resistance and dyslipidemia. ang-(1-7) is also able to improve cerebroprotection against ischemic stroke, besides its effects on learning and memory. the reproductive system can also be affected by ang-(1-7) treatment, with enhanced ovulation, spermatogenesis and sexual steroids synthesis. finally, ang-(1-7) is considered a potential anti-cancer treatment since it is able to inhibit cell proliferation and angiogenesis.[2]fig. 1: formula of angiotensin (1-7)fig. 2: cascade of the processing of angiotensin peptides and their interaction with at1 and at1-7 receptor systems.

Biochem/physiol Actions

Angiotensin I metabolite that is an AT2 receptor agonist.

storage

Store at -20°C

References

1. Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45.2. Danielle G. P., Thiago V., Robson A. S. Angiotensin-(1-7): beyond the cardio-renal actions. Clinical Science (2013) 124, (443–456)

ASP-ARG-VAL-TYR-ILE-HIS-PRO Preparation Products And Raw materials

ASP-ARG-VAL-TYR-ILE-HIS-PRO Suppliers

Global( 206)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
ApexBio Technology LLC +1-832-696-8203 info@apexbt.com United States 477 60
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58

View Lastest Price from ASP-ARG-VAL-TYR-ILE-HIS-PRO manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ASP-ARG-VAL-TYR-ILE-HIS-PRO pictures 2026-09-02 ASP-ARG-VAL-TYR-ILE-HIS-PRO
51833-78-4
$5.00 1KG 98% Henan Fengda Chemical Co., Ltd
Angiotensin (1-7) pictures 2026-07-27 Angiotensin (1-7)
51833-78-4
$33.00-81.00 99.90% 10g TargetMol Chemicals Inc.
ASP-ARG-VAL-TYR-ILE-HIS-PRO pictures 2020-02-18 ASP-ARG-VAL-TYR-ILE-HIS-PRO
51833-78-4
$7.00 1KG 99% 100kg Career Henan Chemical Co
angiotensinii(1-7 angiotensin fragment 1-7 human acetate H2N-DRVYIHP-OH H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-OH (DES-PHE8) ANGIOTENSIN II DRVYIHP ANGIOTENSIN (HUMAN, 1-7) (CANINE, RAT) ANGIOTENSIN CANINE RAT ANGIOTENSIN 1/2 (1-7) ANGIOTENSIN I/II (1-7) ANGIOTENSIN I/II (1-7), HUMAN ANGIOTENSIN II FRAGMENT 1-7 ASP-ARG-VAL-TYR-ILE-HIS-PRO L-ASP-ARG-VAL-TYR-ILE-HIS-PRO Angiotensin Fragment1-7 hydrate acetate salt angiotensin fragment 1-7 acetate hydrate Angiotensin I/II (1-7) trifluoroacetate salt H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH trifluoroacetate salt DRVYIH{D-Ala} Angiotensin 1-7, >98% Angiotensin 1-7 (Angiotensin (1-7) Angiotensin I(1-7)【rat】 Angiotensin II(1-7)【rat】 Aspartyl-argininyl-valinyl-tyrosinyl-isoleucinyl-histidinyl-proline Angiotensin I/II (1-7) Asp-Arg-Val-Tyr-Ile-His-Pro Angiotensin ii (1-7) heptapeptide Angiotensin ii, 5-L-isoleucine-8-de-L-phenylalanine- Angiotensin Fragment1-7 acetate salt hydrate Ang-(1-7) Angiotensin I/II (1-7)|A779|Angiotensin,Canine,Rat Angiotensin (1-7) xTFA salt 1-7-Angiotensin II, 5-L-isoleucine- angiotension 1-7 Angiotensin (1-7) , Canine, Rat Talfirastide Angiotensin (1-7) Angiotensin fragment 1-7 acetate salt Angiotensin (1-7) , Canine, Rat、Angiotensin I/II (1-7) A779 ANGIOTENSIN (1-7) Merotocin Talfirastide 51833-78-4 C41H62N12O11 Peptides Amino Acids and Peptides Angiotensins Biochemicals and Reagents BioChemical API Cardiovescular AngiotensinsPeptides for Cell Biology Angiotensins Neuropeptides Peptides for Cell Biology Angiotensin Peptide