ASP-ARG-VAL-TYR-ILE-HIS-PRO
- CAS No.
- 51833-78-4
- Chemical Name:
- ASP-ARG-VAL-TYR-ILE-HIS-PRO
- Synonyms
- Merotocin;A779;Talfirastide;ANGIOTENSIN (1-7);DRVYIHP;Ang-(1-7);DRVYIH{D-Ala};H2N-DRVYIHP-OH;angiotension 1-7;angiotensinii(1-7
- CBNumber:
- CB6196808
- Molecular Formula:
- C41H62N12O11
- Molecular Weight:
- 899.01
- MDL Number:
- MFCD00153513
- MOL File:
- 51833-78-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >202°C (dec.) |
|---|---|
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | powder |
| pka | 3.29±0.20(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble to 1 mg/ml in water |
| InChIKey | PVHLMTREZMEJCG-UHFFFAOYSA-N |
| SMILES | CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)N3CCCC3C(O)=O |
| EWG's Food Scores | 1 |
| FDA UNII | IJ3FUK8MOF |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P403+P233-P405-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
ASP-ARG-VAL-TYR-ILE-HIS-PRO price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A9202 | Angiotensin Fragment 1-7 acetate salt hydrate ≥90% (HPLC), powder | 51833-78-4 | 1mg | $87.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | A9202 | Angiotensin Fragment 1-7 acetate salt hydrate ≥90% (HPLC), powder | 51833-78-4 | 5mg | $311 | 2026-04-30 | Buy |
| Usbiological | 545083 | Angiotensin 1-7 PurifiedbyProteinAandpeptideaffinitychromatography. | 200ul | $591 | 2026-06-03 | Buy | |
| Usbiological | 545082 | Angiotensin 1-7 PurifiedbyProteinAandpeptideaffinitychromatography. | 200ul | $591 | 2026-06-03 | Buy | |
| Usbiological | 545081 | Angiotensin 1-7 PurifiedbyProteinA/Gaffinitychromatography. | 200ul | $602 | 2026-06-03 | Buy |
ASP-ARG-VAL-TYR-ILE-HIS-PRO Chemical Properties,Uses,Production
Uses
Angiotensin (1-7) can be used in biological study and engineering or chemical process of mechanisms of peptide oxidation by hydroxyl radicals.
Definition
ChEBI: Ile(5)-angiotensin II (1-7) is an angiotensin compound consisting of the linear heptapeptide sequence L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro. It has a role as a vasodilator agent. It is a tautomer of an Ile(5)-angiotensin II (1-7) dizwitterion.
Biological Activity
ang-(1-7) (h - asp - arg - val - tyr - ile - his - pro - oh) is an endogenous peptide fragment that can be produced from ang i or ang ii via endo- or carboxy-peptidases respectively[1].as described for ang ii, ang-(1-7) also has a broad range of effects in different organs and tissues and goes beyond its initially described cardiovascular and renal actions. those effects are mediated by mas and can counter-regulate most of the deleterious effects of ang ii. the interaction ang-(1-7)/mas regulates different signaling pathways, such as pi3k (phosphoinositide 3-kinase)/akt and erk (extracellular signal-regulated kinase) pathways and involves downstream effectors such as no, foxo1 (forkhead box o1) and cox-2 (cyclo-oxygenase-2). through these mechanisms, ang-(1-7) is able to improve pathological conditions including fibrosis and inflammation in organs such as lungs, liver and kidney. [2]in addition, this heptapeptide has positive effects on metabolism, increasing the glucose uptake and lipolysis while decreasing insulin resistance and dyslipidemia. ang-(1-7) is also able to improve cerebroprotection against ischemic stroke, besides its effects on learning and memory. the reproductive system can also be affected by ang-(1-7) treatment, with enhanced ovulation, spermatogenesis and sexual steroids synthesis. finally, ang-(1-7) is considered a potential anti-cancer treatment since it is able to inhibit cell proliferation and angiogenesis.[2]fig. 1: formula of angiotensin (1-7)fig. 2: cascade of the processing of angiotensin peptides and their interaction with at1 and at1-7 receptor systems.
Biochem/physiol Actions
Angiotensin I metabolite that is an AT2 receptor agonist.
storage
Store at -20°C
References
1. Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45.2. Danielle G. P., Thiago V., Robson A. S. Angiotensin-(1-7): beyond the cardio-renal actions. Clinical Science (2013) 124, (443–456)
ASP-ARG-VAL-TYR-ILE-HIS-PRO Preparation Products And Raw materials
ASP-ARG-VAL-TYR-ILE-HIS-PRO Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
View Lastest Price from ASP-ARG-VAL-TYR-ILE-HIS-PRO manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | ASP-ARG-VAL-TYR-ILE-HIS-PRO
51833-78-4
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2026-07-27 | Angiotensin (1-7)
51833-78-4
|
$33.00-81.00 | 99.90% | 10g | TargetMol Chemicals Inc. | ||
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2020-02-18 | ASP-ARG-VAL-TYR-ILE-HIS-PRO
51833-78-4
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-

- ASP-ARG-VAL-TYR-ILE-HIS-PRO
51833-78-4
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-

- Angiotensin (1-7)
51833-78-4
- $33.00-81.00
- 99.90%
- TargetMol Chemicals Inc.
-

- ASP-ARG-VAL-TYR-ILE-HIS-PRO
51833-78-4
- $7.00
- 99%
- Career Henan Chemical Co
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