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4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide

4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide Structure
4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide structure
CAS No.
193551-00-7
Chemical Name:
4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide
Synonyms
CAY10398;4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide;Benzamide, 4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-
CBNumber:
CB4296777
Molecular Formula:
C15H23N3O3
Molecular Weight:
293.36
MDL Number:
MFCD05863979
MOL File:
Mol file
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:44
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4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:5): 300 μg/ml; DMSO: 14 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid

4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 89740 CAY10398 ≥98% 193551-00-7 1mg $24 2026-04-30 Buy
Cayman Chemical 89740 CAY10398 ≥98% 193551-00-7 5mg $98 2026-04-30 Buy
Cayman Chemical 89740 CAY10398 ≥98% 193551-00-7 10mg $173 2026-04-30 Buy
Cayman Chemical 89740 CAY10398 ≥98% 193551-00-7 25mg $376 2026-04-30 Buy
ChemScene CS-0065854 MD 85 193551-00-7 1mg $84 2026-06-04 Buy
Product number Packaging Price Buy
89740 1mg $24 Buy
89740 5mg $98 Buy
89740 10mg $173 Buy
89740 25mg $376 Buy
CS-0065854 1mg $84 Buy

4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide Chemical Properties, Uses, Production

Description

CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 μM. Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-effective compound for the inhibition of HDAC.

Uses

A histone deacetylase (HDAC1) inhibitor

References

[1] STACY W. REMISZEWSKI. Inhibitors of Human Histone Deacetylase: Synthesis and Enzyme and Cellular Activity of Straight Chain Hydroxamates[J]. Journal of Medicinal Chemistry, 2002, 45 4: 753-757. DOI: 10.1021/jm015568c
[2] SYBILLE WITTICH. Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines.[J]. Anti-Cancer Drugs, 2005, 16 6: 635-643. DOI: 10.1097/00001813-200507000-00008
[3] NANIKA COETZEE. Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites.[J]. ACS Applied Electronic Materials, 2020: 2355. DOI: 10.1038/s41598-020-59298-4

4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide Suppliers

Global Suppliers ( 22)
Supplier Tel Email Country ProdList Advantage
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
VDM Biochemicals 64
BOC Sciences 65
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

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CAY10398 Benzamide, 4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]- 4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide 193551-00-7 Other enzyme inhibitors and activators Other Enzyme Inhibitors.