FERUTININ
- CAS No.
- 41743-44-6
- Chemical Name:
- FERUTININ
- Synonyms
- TEFESTROL;FERUTININ;Ferutinin >=98% (HPLC);Ferutinin (high purity);Ferutinin, ERalpha agonist;Ferutinol p-hydroxybenzoate;Jaeschkeanadiol p-hydroxybenzoate;Benzoic acid, 4-hydroxy-, (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester
- CBNumber:
- CB4301709
- Molecular Formula:
- C22H30O4
- Molecular Weight:
- 358.47
- MDL Number:
- MFCD04037015
- MOL File:
- 41743-44-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 489.0±45.0 °C(Predicted) |
|---|---|
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: Soluble |
| form | White to off-white solid |
| pka | 8.12±0.15(Predicted) |
| color | White to off-white |
| InChI | 1S/C22H30O4/c1-14(2)22(25)12-11-21(4)10-9-15(3)13-18(19(21)22)26-20(24)16-5-7-17(23)8-6-16/h5-9,14,18-19,23,25H,10-13H2,1-4H3/t18-,19+,21-,22+/m0/s1 |
| InChIKey | CYSHNJQMYORNJI-YUVXSKOASA-N |
| SMILES | CC1=CC[C@](CC[C@@]2(O)C(C)C)(C)[C@@]2([H])[C@@H](OC(C3=CC=C(O)C=C3)=O)C1 |
| LogP | 5.720 (est) |
| EWG's Food Scores | 1 |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
FERUTININ price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1609 | Ferutinin ≥98% (HPLC) | 41743-44-6 | 5mg | $148 | 2026-04-30 | Buy |
| Cayman Chemical | 16554 | Ferutinin ≥98% | 41743-44-6 | 1mg | $43 | 2026-04-30 | Buy |
| Cayman Chemical | 16554 | Ferutinin ≥98% | 41743-44-6 | 5mg | $127 | 2026-04-30 | Buy |
| Cayman Chemical | 16554 | Ferutinin ≥98% | 41743-44-6 | 10mg | $208 | 2026-04-30 | Buy |
| ChemScene | CS-0093377 | Ferutinin 99.23% | 41743-44-6 | 1mg | $92 | 2026-06-04 | Buy |
FERUTININ Chemical Properties, Uses, Production
Uses
Ferutinin acts as an agonist for estrogen receptor (ER) α. It also increases calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes.
Biological Activity
Ferutinin can suppress tumor development without causing systemic toxicity in various tumor cells and animal cancer models. It possesses estrogenic properties and a protective role against uterine carcinoma. Ferutinin exhibits anti-cancer action in estrogen-dependent breast cancer cells.', 'Ferutinin is a strong agonist for estrogen receptor (ER)α and agonist/antagonist for Erβ with IC50 values of 33.1 nM for ERα and 180.5 nM for Erβ. It has been shown to have both ionophoretic and apoptotic properties. It increases calcium permeability in the lipid bilayer and has been shown to improve bone regeneration in a r at study. It caused significant regression in tumor size in a mouse colon cancer model.
IC 50
ERα: 33.1 nM (IC50); ERβ: 180.5 nM (IC50)
FERUTININ Preparation Products And Raw materials
Raw materials
Preparation Products
FERUTININ Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9382 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7982 | 58 |
| Huai Hua Binfengchem Co., Ltd | 0745-2866851 17711757908 | 3907837691@qq.com | China | 4744 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
