2-[2-(Benzyloxy)ethoxy]ethanol
![2-[2-(Benzyloxy)ethoxy]ethanol Structure](CAS/GIF/2050-25-1.gif)
- CAS No.
- 2050-25-1
- Chemical Name:
- 2-[2-(Benzyloxy)ethoxy]ethanol
- Synonyms
- BnO-PEG2-OH;Bn-PEG2-OH;CAS_2050-25-1;Benzyl-PE2-OH;Benzyl-PEG2-OH;Benzyl-PEG2-alcohol;Benzyl-PEG3-alcohol;2-[2-(Benzyloxy)ethoxy]ethanol;5-(Benzyloxy)-3-oxapentane-1-ol;DI(ETHYLENE GLYCOL) BENZYL ETHER
- CBNumber:
- CB4301749
- Molecular Formula:
- C11H16O3
- Molecular Weight:
- 196.24
- MDL Number:
- MFCD00029649
- MOL File:
- 2050-25-1.mol
- MSDS File:
- SDS
| Boiling point | 80-110 °C0.5 mm Hg(lit.) |
|---|---|
| Density | 1.094 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| Water Solubility | Soluble in water |
| form | clear liquid |
| pka | 14.36±0.10(Predicted) |
| color | Colorless to Almost colorless |
| Specific Gravity | 1.084 |
| InChI | InChI=1S/C11H16O3/c12-6-7-13-8-9-14-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2 |
| InChIKey | LJVNVNLFZQFJHU-UHFFFAOYSA-N |
| SMILES | C(O)COCCOCC1=CC=CC=C1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29094990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
2-[2-(Benzyloxy)ethoxy]ethanol price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 499633 | Di(ethylene glycol) benzyl ether 97% | 2050-25-1 | 25ml | $142 | 2026-04-30 | Buy |
| TCI Chemical | D3408 | Diethylene Glycol Monobenzyl Ether >98.0%(GC) | 2050-25-1 | 25g | $17 | 2026-04-30 | Buy |
| TCI Chemical | D3408 | Diethylene Glycol Monobenzyl Ether >98.0%(GC) | 2050-25-1 | 500g | $62 | 2026-04-30 | Buy |
| ChemScene | CS-0042238 | Diethylene Glycol Monobenzyl Ether ≥97% | 2050-25-1 | 100g | $19 | 2026-06-04 | Buy |
| ChemScene | CS-0042238 | Diethylene Glycol Monobenzyl Ether ≥97% | 2050-25-1 | 500g | $94 | 2026-06-04 | Buy |
2-[2-(Benzyloxy)ethoxy]ethanol Chemical Properties, Uses, Production
Description
Benzyl-PEG3-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Chemical Properties
Colorless to light yellow liquid
Uses
Di(ethylene glycol) benzyl ether may be used as an initiator in the preparation of linear-PLA (poly(L-lactide).
Synthesis
100-44-7
111-46-6
![2-[2-(BENZYLOXY)ETHOXY]ETHANOL](/CAS/GIF/2050-25-1.gif)
2050-25-1
GENERAL METHOD: Dioxane (15 mL), benzyl chloride (25 mmol) and tetrabutylammonium bromide (0.4 g, 1.2 mmol) were sequentially added to a reaction flask, followed by addition of the mixture to a solution of diethylene glycol (75-125 mmol) containing KOH (1.6 g, 27.5 mmol). The reaction system was heated to 100-105 °C and the reaction was continuously stirred for 5-10 hours. Upon completion of the reaction, the reaction mixture was diluted with CHCl3 (15 mL) and water (10 mL). The organic layer was separated, washed with water (3 x 20 mL) and dried over anhydrous Na2SO4. The organic phase was concentrated under reduced pressure and the residue was purified by distillation through a Vigreux column to afford the target product 2-[2-(phenylmethoxy)ethoxy]ethanol. The specific reaction conditions, yields, physicochemical parameters and 1H NMR data are detailed in Table 6 of the literature.
IC 50
PEGs
References
[1] Synthetic Communications, 1986, vol. 16, # 1, p. 19 - 26
[2] Carbohydrate Research, 1986, vol. 150, p. 199 - 212
[3] Russian Chemical Bulletin, 2014, vol. 63, # 11, p. 2445 - 2454
[4] Izv. Akad. Nauk, Ser. Khim., 2014, # 11, p. 2445 - 2454
[5] Analytical Chemistry, 1992, vol. 64, # 15, p. 1685 - 1690
2-[2-(Benzyloxy)ethoxy]ethanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9848 | 55 |
| Noventek Pharmaceutical Technology Co.,Ltd | 0555-8220886 | sales@noventekpharm.com | China | 176 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
View Latest Price from 2-[2-(Benzyloxy)ethoxy]ethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-28 | BnO-PEG2-OH
2050-25-1
|
1g | 98% | 500kg | LAURENT |
-
- BnO-PEG2-OH
2050-25-1
- 98%
- LAURENT
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