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2-[2-(BENZYLOXY)ETHOXY]ETHANOL

CAS No.
2050-25-1
Chemical Name:
2-[2-(BENZYLOXY)ETHOXY]ETHANOL
Synonyms
Bn-PEG2-OH;BnO-PEG2-OH;CAS_2050-25-1;Benzyl-PE2-OH;Benzyl-PEG2-OH;Benzyl-PEG2-alcohol;Benzyl-PEG3-alcohol;2-[2-(BENZYLOXY)ETHOXY]ETHANOL;5-(Benzyloxy)-3-oxapentane-1-ol;DI(ETHYLENE GLYCOL) BENZYL ETHER
CBNumber:
CB4301749
Molecular Formula:
C11H16O3
Molecular Weight:
196.24
MDL Number:
MFCD00029649
MOL File:
2050-25-1.mol
MSDS File:
SDS
Last updated:2026-01-28 14:58:11
Product description Number Pack Size Price
Di(ethylene glycol) benzyl ether 97% 499633 25ml $133
Diethylene Glycol Monobenzyl Ether >98.0%(GC) D3408 25g $49
Diethylene Glycol Monobenzyl Ether >98.0%(GC) D3408 500g $109
Diethylene Glycol Monobenzyl Ether D446328 500mg $60
Diethylene Glycol Monobenzyl Ether Y4930 100g $67
More product size

2-[2-(BENZYLOXY)ETHOXY]ETHANOL Properties

Boiling point 80-110 °C0.5 mm Hg(lit.)
Density 1.094 g/mL at 25 °C(lit.)
refractive index n20/D 1.51(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
Water Solubility Soluble in water
pka 14.36±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
Specific Gravity 1.084
InChI InChI=1S/C11H16O3/c12-6-7-13-8-9-14-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2
InChIKey LJVNVNLFZQFJHU-UHFFFAOYSA-N
SMILES C(O)COCCOCC1=CC=CC=C1
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261
PPE Eyeshields, Gloves
Safety Statements  24/25
WGK Germany  3
HS Code  29094990
Storage Class 10 - Combustible liquids
NFPA 704
1
0 0

2-[2-(BENZYLOXY)ETHOXY]ETHANOL price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 499633 Di(ethylene glycol) benzyl ether 97% 2050-25-1 25ml $133 2025-07-31 Buy
TCI Chemical D3408 Diethylene Glycol Monobenzyl Ether >98.0%(GC) 2050-25-1 25g $49 2025-07-31 Buy
TCI Chemical D3408 Diethylene Glycol Monobenzyl Ether >98.0%(GC) 2050-25-1 500g $109 2025-07-31 Buy
TRC D446328 Diethylene Glycol Monobenzyl Ether 2050-25-1 500mg $60 2021-12-16 Buy
AK Scientific Y4930 Diethylene Glycol Monobenzyl Ether 2050-25-1 100g $67 2021-12-16 Buy
Product number Packaging Price Buy
499633 25ml $133 Buy
D3408 25g $49 Buy
D3408 500g $109 Buy
D446328 500mg $60 Buy
Y4930 100g $67 Buy

2-[2-(BENZYLOXY)ETHOXY]ETHANOL Chemical Properties,Uses,Production

Description

Benzyl-PEG3-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Chemical Properties

Colorless to light yellow liquid

Uses

Di(ethylene glycol) benzyl ether may be used as an initiator in the preparation of linear-PLA (poly(L-lactide).

Synthesis

Benzyl chloride

100-44-7

Diethylene glycol

111-46-6

2-[2-(BENZYLOXY)ETHOXY]ETHANOL

2050-25-1

GENERAL METHOD: Dioxane (15 mL), benzyl chloride (25 mmol) and tetrabutylammonium bromide (0.4 g, 1.2 mmol) were sequentially added to a reaction flask, followed by addition of the mixture to a solution of diethylene glycol (75-125 mmol) containing KOH (1.6 g, 27.5 mmol). The reaction system was heated to 100-105 °C and the reaction was continuously stirred for 5-10 hours. Upon completion of the reaction, the reaction mixture was diluted with CHCl3 (15 mL) and water (10 mL). The organic layer was separated, washed with water (3 x 20 mL) and dried over anhydrous Na2SO4. The organic phase was concentrated under reduced pressure and the residue was purified by distillation through a Vigreux column to afford the target product 2-[2-(phenylmethoxy)ethoxy]ethanol. The specific reaction conditions, yields, physicochemical parameters and 1H NMR data are detailed in Table 6 of the literature.

IC 50

PEGs

References

[1] Synthetic Communications, 1986, vol. 16, # 1, p. 19 - 26
[2] Carbohydrate Research, 1986, vol. 150, p. 199 - 212
[3] Russian Chemical Bulletin, 2014, vol. 63, # 11, p. 2445 - 2454
[4] Izv. Akad. Nauk, Ser. Khim., 2014, # 11, p. 2445 - 2454
[5] Analytical Chemistry, 1992, vol. 64, # 15, p. 1685 - 1690

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View Lastest Price from 2-[2-(BENZYLOXY)ETHOXY]ETHANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BnO-PEG2-OH pictures 2026-01-28 BnO-PEG2-OH
2050-25-1
US $0.00-0.00 / g 1g 98% 500kg LAURENT

2-[2-(BENZYLOXY)ETHOXY]ETHANOL Spectrum

2-[2-(Benzyloxy)ethoxy]ethanol 98% 2-[2-(BENZYLOXY)ETHOXY]ETHANOL 2-[2-(phenylmethoxy)ethoxy]-Ethanol DI(ETHYLENE GLYCOL) BENZYL ETHER DIETHYLENE GLYCOL MONOBENZYL ETHER Benzyl-PEG2-alcohol Di(ethylene glycol) benzyl ether 97% 5-(Benzyloxy)-3-oxapentane-1-ol Benzyl-PEG3-alcohol CAS_2050-25-1 DiethyleneGlycolMonobenzylEther> Ethanol, 2-[2-(phenylmethoxy)ethoxy]- Benzyl-PE2-OH Benzyl-PEG2-OH Bn-PEG2-OH BnO-PEG2-OH 2050-25-1 C6H5CH2OCH2CH2OCH2CH2OH Organic Building Blocks Oxygen Compounds Alcohols Building Blocks C9 to C30 peg