- BnO-PEG2-OH
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2026-01-28
- CAS:2050-25-1
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 500kg
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| | 2-[2-(Benzyloxy)ethoxy]ethanol Basic information |
| Product Name: | 2-[2-(Benzyloxy)ethoxy]ethanol | | Synonyms: | 2-[2-(Benzyloxy)ethoxy]ethanol 98%;2-[2-(phenylmethoxy)ethoxy]-Ethanol;DI(ETHYLENE GLYCOL) BENZYL ETHER;DIETHYLENE GLYCOL MONOBENZYL ETHER;Benzyl-PEG2-alcohol;Di(ethylene glycol) benzyl ether 97%;5-(Benzyloxy)-3-oxapentane-1-ol;Benzyl-PEG3-alcohol | | CAS: | 2050-25-1 | | MF: | C11H16O3 | | MW: | 196.24 | | EINECS: | | | Product Categories: | peg | | Mol File: | 2050-25-1.mol | ![2-[2-(Benzyloxy)ethoxy]ethanol Structure](CAS/GIF/2050-25-1.gif) |
| | 2-[2-(Benzyloxy)ethoxy]ethanol Chemical Properties |
| Boiling point | 80-110 °C0.5 mm Hg(lit.) | | density | 1.094 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.51(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | Water Solubility | Soluble in water | | form | clear liquid | | pka | 14.36±0.10(Predicted) | | color | Colorless to Almost colorless | | Specific Gravity | 1.084 | | InChI | InChI=1S/C11H16O3/c12-6-7-13-8-9-14-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2 | | InChIKey | LJVNVNLFZQFJHU-UHFFFAOYSA-N | | SMILES | C(O)COCCOCC1=CC=CC=C1 |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29094990 | | Storage Class | 10 - Combustible liquids |
| | 2-[2-(Benzyloxy)ethoxy]ethanol Usage And Synthesis |
| Description | Benzyl-PEG3-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | | Chemical Properties | Colorless to light yellow liquid | | Uses | Di(ethylene glycol) benzyl ether may be used as an initiator in the preparation of linear-PLA (poly(L-lactide). | | Synthesis | GENERAL METHOD: Dioxane (15 mL), benzyl chloride (25 mmol) and tetrabutylammonium bromide (0.4 g, 1.2 mmol) were sequentially added to a reaction flask, followed by addition of the mixture to a solution of diethylene glycol (75-125 mmol) containing KOH (1.6 g, 27.5 mmol). The reaction system was heated to 100-105 °C and the reaction was continuously stirred for 5-10 hours. Upon completion of the reaction, the reaction mixture was diluted with CHCl3 (15 mL) and water (10 mL). The organic layer was separated, washed with water (3 x 20 mL) and dried over anhydrous Na2SO4. The organic phase was concentrated under reduced pressure and the residue was purified by distillation through a Vigreux column to afford the target product 2-[2-(phenylmethoxy)ethoxy]ethanol. The specific reaction conditions, yields, physicochemical parameters and 1H NMR data are detailed in Table 6 of the literature. | | IC 50 | PEGs | | References | [1] Synthetic Communications, 1986, vol. 16, # 1, p. 19 - 26
[2] Carbohydrate Research, 1986, vol. 150, p. 199 - 212
[3] Russian Chemical Bulletin, 2014, vol. 63, # 11, p. 2445 - 2454
[4] Izv. Akad. Nauk, Ser. Khim., 2014, # 11, p. 2445 - 2454
[5] Analytical Chemistry, 1992, vol. 64, # 15, p. 1685 - 1690 |
| | 2-[2-(Benzyloxy)ethoxy]ethanol Preparation Products And Raw materials |
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