Boc-Val-Cit-PABA
- CAS No.
- 870487-09-5
- Chemical Name:
- Boc-Val-Cit-PABA
- Synonyms
- Boc-Gly-Gly-Phe-Gly;tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;Boc-Val-Cit-PAB-OH;Boc-Val-Cit-PABA;Pentanoicacid,2,6-dioxo-,methylester;Inhibitor,inhibit,ADC Linkers,Boc Val Cit PAB,BocValCitPAB,Antibody-drug conjugates linkers;(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide;N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide;L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
- CBNumber:
- CB43059339
- Molecular Formula:
- C23H37N5O6
- Molecular Weight:
- 479.57
- MDL Number:
- MFCD22381208
- MOL File:
- 870487-09-5.mol
- MSDS File:
- SDS
| Boiling point | 771.3±60.0 °C(Predicted) |
|---|---|
| Density | 1.209±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO : 100 mg/mL (208.52 mM; Need ultrasonic) |
| pka | 11.25±0.46(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | NTAKMIJAGHASRI-ROUUACIJSA-N |
| SMILES | C(N)(=O)[C@H](CCCNC(N)=O)N(C(=O)[C@H](C(C)C)NC(OC(C)(C)C)=O)C1=CC=C(CO)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Boc-Val-Cit-PABA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemPep | 181181-5G | Boc-Val-Cit-PAB | 870487-09-5 | 5g | $1600 | 2026-06-04 | Buy |
| ChemPep | 181181-25G | Boc-Val-Cit-PAB | 870487-09-5 | 25g | $4000 | 2026-06-04 | Buy |
| ChemPep | 181181-1G | Boc-Val-Cit-PAB | 870487-09-5 | 1g | $500 | 2026-06-04 | Buy |
| ChemScene | CS-0114767 | Boc-Val-Cit-PAB ≥98% | 870487-09-5 | 100mg | $86 | 2026-06-04 | Buy |
| ChemScene | CS-0114767 | Boc-Val-Cit-PAB ≥98% | 870487-09-5 | 250mg | $152 | 2026-06-04 | Buy |
Boc-Val-Cit-PABA Chemical Properties, Uses, Production
Description
Boc-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit peptide will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition.
Uses
Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50
Protease Cleavable Linker; Cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Boc-Val-Cit-PABA Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. | 13632427122;13414494621 | chenchao02lzu@126.com | China | 137 | 58 |
| SuZhou JianHua Pharmaceutical Co. Ltd | 13666392288 | jhyylcj@163.com | China | 64 | 58 |
| Heze Development Zone chuangli Chemical Co., Ltd. | 0530-+86-530-529 6766,+86-15666160102 15666160102 | info@chuangli-chem.com | China | 849 | 55 |
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 1846 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
| Tianjin Chempharmatech Co.,Ltd. | 022-66211079 13212288319 | sales@chempharmatech.com | China | 943 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Shanghai Send Pharmaceutical Technology Co., Ltd. | 021-58088081 18317173152 | Hailey@shsendpharm.com | China | 843 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from Boc-Val-Cit-PABA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-04-22 | Boc-Val-Cit-PAB
870487-09-5
|
$32.00-46.00 | 99.34% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2025-06-07 | Boc-Val-Cit-PAB
870487-09-5
|
5g | >99.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-

- Boc-Val-Cit-PAB
870487-09-5
- $32.00-46.00
- 99.34%
- TargetMol Chemicals Inc.
-

- Boc-Val-Cit-PAB
870487-09-5
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.





