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Boc-Val-Cit-PABA

CAS No.
870487-09-5
Chemical Name:
Boc-Val-Cit-PABA
Synonyms
Boc-Gly-Gly-Phe-Gly;tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;Boc-Val-Cit-PAB-OH;Boc-Val-Cit-PABA;Pentanoicacid,2,6-dioxo-,methylester;Inhibitor,inhibit,ADC Linkers,Boc Val Cit PAB,BocValCitPAB,Antibody-drug conjugates linkers;(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide;N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide;L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
CBNumber:
CB43059339
Molecular Formula:
C23H37N5O6
Molecular Weight:
479.57
MDL Number:
MFCD22381208
MOL File:
870487-09-5.mol
MSDS File:
SDS
Last updated:2026-05-28 02:47:12

Boc-Val-Cit-PABA Properties

Boiling point 771.3±60.0 °C(Predicted)
Density 1.209±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO : 100 mg/mL (208.52 mM; Need ultrasonic)
pka 11.25±0.46(Predicted)
form Solid
color White to off-white
InChIKey NTAKMIJAGHASRI-ROUUACIJSA-N
SMILES C(N)(=O)[C@H](CCCNC(N)=O)N(C(=O)[C@H](C(C)C)NC(OC(C)(C)C)=O)C1=CC=C(CO)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Boc-Val-Cit-PABA price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemPep 181181-5G Boc-Val-Cit-PAB 870487-09-5 5g $1600 2026-06-04 Buy
ChemPep 181181-25G Boc-Val-Cit-PAB 870487-09-5 25g $4000 2026-06-04 Buy
ChemPep 181181-1G Boc-Val-Cit-PAB 870487-09-5 1g $500 2026-06-04 Buy
ChemScene CS-0114767 Boc-Val-Cit-PAB ≥98% 870487-09-5 100mg $86 2026-06-04 Buy
ChemScene CS-0114767 Boc-Val-Cit-PAB ≥98% 870487-09-5 250mg $152 2026-06-04 Buy
Product number Packaging Price Buy
181181-5G 5g $1600 Buy
181181-25G 25g $4000 Buy
181181-1G 1g $500 Buy
CS-0114767 100mg $86 Buy
CS-0114767 250mg $152 Buy

Boc-Val-Cit-PABA Chemical Properties, Uses, Production

Description

Boc-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit peptide will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition.

Uses

Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Protease Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Boc-Val-Cit-PABA Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 105)
Supplier Tel Email Country ProdList Advantage
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. 13632427122;13414494621 chenchao02lzu@126.com China 137 58
SuZhou JianHua Pharmaceutical Co. Ltd 13666392288 jhyylcj@163.com China 64 58
Heze Development Zone chuangli Chemical Co., Ltd. 0530-+86-530-529 6766,+86-15666160102 15666160102 info@chuangli-chem.com China 849 55
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 1846 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9510 58
Tianjin Chempharmatech Co.,Ltd. 022-66211079 13212288319 sales@chempharmatech.com China 943 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Shanghai Send Pharmaceutical Technology Co., Ltd. 021-58088081 18317173152 Hailey@shsendpharm.com China 843 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60

View Latest Price from Boc-Val-Cit-PABA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Val-Cit-PAB pictures 2026-04-22 Boc-Val-Cit-PAB
870487-09-5
$32.00-46.00 99.34% 10g TargetMol Chemicals Inc.
Boc-Val-Cit-PAB pictures 2025-06-07 Boc-Val-Cit-PAB
870487-09-5
5g >99.00% 5g Xian confluore Biological Technology Co., Ltd.
  • Boc-Val-Cit-PAB pictures
  • Boc-Val-Cit-PAB
    870487-09-5
  • $0.00
  • >99.00%
  • Xian confluore Biological Technology Co., Ltd.

Boc-Val-Cit-PABA Spectrum

Boc-Val-Cit-PABA N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide (S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- Pentanoicacid,2,6-dioxo-,methylester Inhibitor,inhibit,ADC Linkers,Boc Val Cit PAB,BocValCitPAB,Antibody-drug conjugates linkers Boc-Gly-Gly-Phe-Gly Boc-Val-Cit-PAB-OH tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate 870487-09-5 C23H37N5O6 Linker ADC LINKER ADCs