Acid-PEG3-t-butyl ester
- CAS No.
- 1807539-06-5
- Chemical Name:
- Acid-PEG3-t-butyl ester
- Synonyms
- 2,2-Dimethyl-4-oxo-3,7,10,13-tetraoxahexadecan-16-oic acid;Acid-PEG3-C2-Boc;COOH-PEG3-COOtBu;COOH-PEG3-OtBu;HOOC-PEG2-COOtBu;Acid-PEG3-t-Bu Ester;Acid-PEG3-t-butyl ester;Carboxy-PEG3-tert-butyl Ester;HOOCCH2CH2O-PEG2-CH2CH2COOtBu;4,7,10,14-Tetraoxahexadecanoic acid, 15,15-dimethyl-13-oxo-
- CBNumber:
- CB43062292
- Molecular Formula:
- C14H26O7
- Molecular Weight:
- 306.35
- MDL Number:
- MFCD28015771
- MOL File:
- 1807539-06-5.mol
- MSDS File:
- SDS
| Boiling point | 423.2±35.0 °C(Predicted) |
|---|---|
| Density | 1.106±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| InChI | InChI=1S/C14H26O7/c1-14(2,3)21-13(17)5-7-19-9-11-20-10-8-18-6-4-12(15)16/h4-11H2,1-3H3,(H,15,16) |
| InChIKey | VDWZJPCGUNJFEE-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCOCCOCCOCCC(=O)OC(C)(C)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| HS Code | 9999999999 |
Acid-PEG3-t-butyl ester price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | HXC53906 | Acid-PEG3-t-butyl ester | 1807539-06-5 | 250mg | $1080 | 2026-06-04 | Buy |
| Biosynth | HXC53906 | Acid-PEG3-t-butyl ester | 1807539-06-5 | 500mg | $1500 | 2026-06-04 | Buy |
| ChemScene | CS-0109067 | Acid-PEG3-C2-Boc ≥97% | 1807539-06-5 | 250mg | $49 | 2026-06-04 | Buy |
| ChemScene | CS-0109067 | Acid-PEG3-C2-Boc ≥97% | 1807539-06-5 | 1g | $122 | 2026-06-04 | Buy |
| ChemScene | CS-0109067 | Acid-PEG3-C2-Boc ≥97% | 1807539-06-5 | 5g | $446 | 2026-06-04 | Buy |
Acid-PEG3-t-butyl ester Chemical Properties,Uses,Production
Description
Acid-PEG3-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].
IC 50
PEGs; Alkyl/ether
References
[1] Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.
[2] Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO 2018204416 A1.
Acid-PEG3-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD | 17882285575 | 1276966012@qq.com | China | 397 | 58 |
| Jinan Junhe Pharmaceutical Co., Ltd | +86-13053355392 +86-13053355392 | 957395144@qq.com | China | 279 | 58 |
| Nanjing Junnahe Biopharmaceutical Co., Ltd | 025-58367986 17351780683 | amy.xiang@ally-chem.com | China | 354 | 60 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
View Lastest Price from Acid-PEG3-t-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | Acid-PEG3-C2-Boc
1807539-06-5
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | COOH-PEG3-COOtBu
1807539-06-5
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Acid-PEG3-C2-Boc
1807539-06-5
- $0.00
- TargetMol Chemicals Inc.
-
- COOH-PEG3-COOtBu
1807539-06-5
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
