Acid-PEG5-t-butyl ester
- CAS No.
- 1309460-29-4
- Chemical Name:
- Acid-PEG5-t-butyl ester
- Synonyms
- 2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid;COOH-PEG5-COOtBu;COOH-PEG5-OtBu;Acid-PEG5-C2-Boc;HOOC-PEG4-COOtBu;Acid-PEG5-t-Bu Ester;Acid-PEG5-t-butyl ester;Carboxy-PEG5-tert-butyl Ester;HOOCCH2CH2O-PEG4-CH2CH2COOtBu;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester
- CBNumber:
- CB33062295
- Molecular Formula:
- C18H34O9
- Molecular Weight:
- 394.46
- MDL Number:
- MFCD18916989
- MOL File:
- 1309460-29-4.mol
- MSDS File:
- SDS
| Boiling point | 495.2±45.0 °C(Predicted) |
|---|---|
| Density | 1.109±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| InChI | InChI=1S/C18H34O9/c1-18(2,3)27-17(21)5-7-23-9-11-25-13-15-26-14-12-24-10-8-22-6-4-16(19)20/h4-15H2,1-3H3,(H,19,20) |
| InChIKey | ILIIUHKWCBCCNI-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCC(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Acid-PEG5-t-butyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114562 | Acid-PEG5-C2-Boc ≥98% | 1309460-29-4 | 100mg | $78 | 2026-06-04 | Buy |
| ChemScene | CS-0114562 | Acid-PEG5-C2-Boc ≥98% | 1309460-29-4 | 250mg | $128 | 2026-06-04 | Buy |
| ChemScene | CS-0114562 | Acid-PEG5-C2-Boc ≥98% | 1309460-29-4 | 1g | $321 | 2026-06-04 | Buy |
| ChemScene | CS-0114562 | Acid-PEG5-C2-Boc ≥98% | 1309460-29-4 | 5g | $714 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1360 | Carboxy-PEG5-t-butyl ester 95% | 1309460-29-4 | 100mg | $97 | 2026-06-04 | Buy |
Acid-PEG5-t-butyl ester Chemical Properties,Uses,Production
Description
Acid-PEG5-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG5-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD | 17882285575 | 1276966012@qq.com | China | 397 | 58 |
| Nanjing Junnahe Biopharmaceutical Co., Ltd | 025-58367986 17351780683 | amy.xiang@ally-chem.com | China | 354 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Uchem Inc. | 15618758386 15618758386 | sales3@myuchem.com | China | 1990 | 55 |
| ShangHai ShuaiDian MEDICAL TECHNOLOGY CO.,LTD. | 15821556986 | shshuaidian@126.com | China | 142 | 58 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
| Hangzhou HanLai Biochemical Technology Co., Ltd. | 571-86101219 18768477782 | sales09@leobiochem.com | China | 433 | 58 |
| Aikon International Limited | 025-58859352 15955137747 | sales01@aikonchem.com | China | 16021 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
View Lastest Price from Acid-PEG5-t-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Acid-PEG5-C2-Boc
1309460-29-4
|
$42.00-66.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | COOH-PEG5-COOtBu
1309460-29-4
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Acid-PEG5-C2-Boc
1309460-29-4
- $42.00-66.00
- TargetMol Chemicals Inc.
-
- COOH-PEG5-COOtBu
1309460-29-4
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
