Bis-PEG2-acid
- CAS No.
- 19364-66-0
- Chemical Name:
- Bis-PEG2-acid
- Synonyms
- 3,3'-(ethane-1,2-diylbis(oxy))dipropionic acid;COOH-PEG1-COOH;3-[2-(2-carboxyethoxy)ethoxy]propanoic acid;Di-Acid-PEG2;Bis-PEG2-COOH;Bis-PEG2-acid;HOOCCH2CH2O-PEG1-CH2CH2COOH;1,2-Bis(2-carboxyethoxy)ethane;Ethyleneglycol-bis(propionic acid);3,3'-[ethane-1,2-diylbis(oxy)]dipropanoic acid
- CBNumber:
- CB43062409
- Molecular Formula:
- C8H14O6
- Molecular Weight:
- 206.19
- MDL Number:
- MFCD22056315
- MOL File:
- 19364-66-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 66 °C |
|---|---|
| Boiling point | 407.1±35.0 °C(Predicted) |
| Density | 1.0869 g/cm3(Temp: 4 °C) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in Water, DMF, DMSO |
| pka | 3.97±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChI | 1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12) |
| InChIKey | BOXWYBCUJGWEOJ-UHFFFAOYSA-N |
| SMILES | OC(CCOCCOCCC(O)=O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
Bis-PEG2-acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 516834 | 3,6-Dioxaoctanedioic acid (Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-) ≥95% | 19364-66-0 | 1g | $425 | 2026-06-03 | Buy |
| Biosynth | DPG-6002 | Bis-dPEG®2-Acid | 19364-66-0 | 100mg | $208 | 2026-06-04 | Buy |
| Biosynth | DPG-6002 | Bis-dPEG®2-Acid | 19364-66-0 | 1000mg | $660 | 2026-06-04 | Buy |
| ChemScene | CS-0046398 | Bis-PEG2-acid ≥97% | 19364-66-0 | 100mg | $17 | 2026-06-04 | Buy |
| ChemScene | CS-0046398 | Bis-PEG2-acid ≥97% | 19364-66-0 | 250mg | $20 | 2026-06-04 | Buy |
Bis-PEG2-acid Chemical Properties, Uses, Production
Description
Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264
Bis-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Feihe Pharmatech Co.,Ltd | 021-33926058 18030239092 | xuxin@fenhechem.com | China | 161 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9957 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
View Latest Price from Bis-PEG2-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid
19364-66-0
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2025-06-07 | Bis-PEG2-acid
19364-66-0
|
5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-
- 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid
19364-66-0
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- Bis-PEG2-acid
19364-66-0
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
