ChemicalBook >> CAS DataBase List >>Bis-PEG2-acid
Bis-PEG2-acid
- CAS No.
- 19364-66-0
- Chemical Name:
- Bis-PEG2-acid
- Synonyms
- 3,3'-(ethane-1,2-diylbis(oxy))dipropionic acid;COOH-PEG1-COOH;3-[2-(2-carboxyethoxy)ethoxy]propanoic acid;Di-Acid-PEG2;Bis-PEG2-COOH;Bis-PEG2-acid;HOOCCH2CH2O-PEG1-CH2CH2COOH;1,2-Bis(2-carboxyethoxy)ethane;Ethyleneglycol-bis(propionic acid);3,3'-[ethane-1,2-diylbis(oxy)]dipropanoic acid
- CBNumber:
- CB43062409
- Molecular Formula:
- C8H14O6
- Molecular Weight:
- 206.19
- MDL Number:
- MFCD22056315
- MOL File:
- 19364-66-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 02:48:54
| Product description | Number | Pack Size | Price |
| 3,6-Dioxaoctanedioic acid (Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-) ≥95% | 516834 | 1g | $425 |
| Bis-dPEG®2-Acid | DPG-6002 | 100mg | $208 |
| Bis-dPEG®2-Acid | DPG-6002 | 1000mg | $660 |
| Bis-PEG2-acid ≥97% | CS-0046398 | 100mg | $17 |
| Bis-PEG2-acid ≥97% | CS-0046398 | 250mg | $20 |
| More product size | |||
| Melting point | 66 °C |
|---|---|
| Boiling point | 407.1±35.0 °C(Predicted) |
| Density | 1.0869 g/cm3(Temp: 4 °C) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in Water, DMF, DMSO |
| pka | 3.97±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChI | 1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12) |
| InChIKey | BOXWYBCUJGWEOJ-UHFFFAOYSA-N |
| SMILES | OC(CCOCCOCCC(O)=O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
Bis-PEG2-acid price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 516834 | 3,6-Dioxaoctanedioic acid (Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-) ≥95% | 19364-66-0 | 1g | $425 | 2026-06-03 | Buy |
| Biosynth | DPG-6002 | Bis-dPEG®2-Acid | 19364-66-0 | 100mg | $208 | 2026-06-04 | Buy |
| Biosynth | DPG-6002 | Bis-dPEG®2-Acid | 19364-66-0 | 1000mg | $660 | 2026-06-04 | Buy |
| ChemScene | CS-0046398 | Bis-PEG2-acid ≥97% | 19364-66-0 | 100mg | $17 | 2026-06-04 | Buy |
| ChemScene | CS-0046398 | Bis-PEG2-acid ≥97% | 19364-66-0 | 250mg | $20 | 2026-06-04 | Buy |
Bis-PEG2-acid Chemical Properties,Uses,Production
Description
Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264
Synthesis of Bis-PEG2-acid from Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-, 1,1'-diethyl ester
Bis-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 90)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5746 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | changaiwei@sinopeg.com | China | 1125 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9945 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
View Lastest Price from Bis-PEG2-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid
19364-66-0
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2025-06-07 | Bis-PEG2-acid
19364-66-0
|
5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-
- 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid
19364-66-0
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- Bis-PEG2-acid
19364-66-0
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
Bis-PEG2-acid
HOOCCH2CH2O-PEG1-CH2CH2COOH
3,3'-[ethane-1,2-diylbis(oxy)]dipropanoic acid
Bis-PEG2-COOH
1,2-Bis(2-carboxyethoxy)ethane
Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-
Di-Acid-PEG2
HOOCCH2CH2O-PEG1-CH2CH2COOH/Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-
Ethyleneglycol-bis(propionic acid)
3,3'-(ethane-1,2-diylbis(oxy))dipropionic acid
3-[2-(2-carboxyethoxy)ethoxy]propanoic acid
COOH-PEG1-COOH
19364-66-0
peg
