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Bis-PEG4-acid

Bis-PEG4-acid structure

CAS No.: 96517-92-9

Chemical Name:: Bis-PEG4-acid

Synonyms: COOH-PEG2-COOH;Bis-PEG3-acid;3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid;Di-Acid-PEG3;Bis-PEG3-COOH;HOOC-PEG2-COOH;HOOC-PEG2-COOHE;Bis-PEG3-acid ，S1350;HOOCCH2CH2O-PEG2-CH2CH2COOH;4,7,10-trioxa-tridecanedioic acid

CBNumber:: CB73051642

Molecular Formula:: C10H18O7

Molecular Weight:: 250.25

MDL Number:: MFCD22056316

MOL File:: 96517-92-9.mol

MSDS File:: SDS

Last updated:2026-05-28 02:57:13

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Bis-PEG4-acid Properties

Boiling point	445.4±40.0 °C(Predicted)
Density	1.239±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Soluble in Water, DMSO, DMF
pka	3.97±0.10(Predicted)
form	Solid-Liquid Mixture
color	Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

Bis-PEG4-acid price More Price(49)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	516852	Bis-PEG3-Carboxyl (Bis-PEG3-acid) ≥95%	96517-92-9	1g	$469	2026-06-03	Buy
Biosynth	DPG-6018	Bis-dPEG®4-Acid	96517-92-9	100mg	$208	2026-06-04	Buy
Biosynth	DPG-6018	Bis-dPEG®4-Acid	96517-92-9	1000mg	$740	2026-06-04	Buy
ChemScene	CS-0107997	Bis-PEG3-acid ≥97%	96517-92-9	250mg	$16	2026-06-04	Buy
ChemScene	CS-0107997	Bis-PEG3-acid ≥97%	96517-92-9	1g	$37	2026-06-04	Buy

Product number	Packaging	Price	Buy
516852	1g	$469	Buy
DPG-6018	100mg	$208	Buy
DPG-6018	1000mg	$740	Buy
CS-0107997	250mg	$16	Buy
CS-0107997	1g	$37	Buy

Bis-PEG4-acid Chemical Properties,Uses,Production

Description

Bis-PEG3-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264

Bis-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Bis-PEG4-acid Suppliers

Global( 90)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Innochem(Beijing) Technology Co.,Ltd.	010-56541685 13070143590	sales@innochem.cn	China	172	57
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
Hygeia (Chengdu) pharmaceutical technique Co., Ltd	028-84502008 13568869383	sales@hygeiapharm.com	China	291	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Hunan HuaTeng Pharmaceutical Co., Ltd.,	400-8592883 15367835770	sales@huatengsci.com	China	5869	58
Borenpharm Co., Ltd	027-65563561	sales@borenpharm.com	China	1245	55
Zhengzhou Acme Chemical Co., Ltd.	0371-0371-55629727 13323845623	2885676761@qq.com	China	9948	58
Amatek Scientific Co. Ltd.	0512-56316828 400-867-5858;400-867-5858	info@amateksci.com	China	28760	58
Hangzhou HanLai Biochemical Technology Co., Ltd.	571-86101219 18768477782	sales09@leobiochem.com	China	433	58
Aikon International Limited	025-66113011 19370895928	qzhang@aikonchem.com	China	15390	58

Supplier	Advantage
Innochem(Beijing) Technology Co.,Ltd.	57
T&W GROUP	58
Hygeia (Chengdu) pharmaceutical technique Co., Ltd	55
Bide Pharmatech Ltd.	60
Hunan HuaTeng Pharmaceutical Co., Ltd.,	58
Borenpharm Co., Ltd	55
Zhengzhou Acme Chemical Co., Ltd.	58
Amatek Scientific Co. Ltd.	58
Hangzhou HanLai Biochemical Technology Co., Ltd.	58
Aikon International Limited	58

View Lastest Price from Bis-PEG4-acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	Bis-PEG3-acid 96517-92-9				10g	TargetMol Chemicals Inc.
	2025-06-07	Bis-PEG3-acid 96517-92-9		10g	>98.00%	10g	Xian confluore Biological Technology Co., Ltd.

Bis-PEG3-acid
96517-92-9
$0.00
TargetMol Chemicals Inc.

Bis-PEG3-acid
96517-92-9
$0.00
>98.00%
Xian confluore Biological Technology Co., Ltd.

Bis-PEG4-acid Spectrum

Bis-PEG4-acid(96517-92-9)¹HNMR

96517-92-9(Bis-PEG4-acid)Related Search:

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alpha-(2-Carboxyethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl) Bis-PEG4-t-butyl ester Bis-PEG10-acid alpha, oMega-Dipropionic acid hexaethylene glycol Bis-PEG6-t-butyl ester

Bis-PEG1-NHS ester Bis-PEG5-t-butyl ester Bis-PEG9-t-butyl ester

1of4

Bis-PEG3-COOH 3,3'-[oxybis(ethane-2,1-diyloxy)]dipropanoic acid 3,3'-((Oxybis(ethane-2,1-diyl))bis(oxy))dipropanoic acid 4,7,10-trioxa-tridecanedioic acid HOOCCH2CH2O-PEG2-CH2CH2COOH Propanoic acid, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- Di-Acid-PEG3 HOOCCH2CH2O-PEG2-CH2CH2COOH/4,7,10-Trioxatridecanedioic acid 3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]propanoic acid Bis-PEG3-acid ，S1350 HOOC-PEG2-COOHE HOOC-PEG2-COOH 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid Bis-PEG3-acid COOH-PEG2-COOH 96517-92-9